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Eslicarbazepine Acetate (BIA 2 093) as Therapy for Refractory Partial Seizures in Children

ClinicalTrials.gov study NCT00988156. IPD Sharing: Not stated. Countries: 21. Publications: 1.

Generation of Prediction Equations for BIA of the Elderly

ClinicalTrials.gov study NCT04028648. IPD Sharing: Not stated. Countries: 1. Publications: 1.

Efficacy and Safety Study of BIA 2-093 in Combination With Other Anti-Epileptic Drugs to Treat Partial Epilepsy

ClinicalTrials.gov study NCT00957047. IPD Sharing: Not stated. Countries: 1. Publications: 1.

Effects of Eslicarbazepine Acetate (Esl, Bia 2-093) on Cognitive Function in Children With Partial Onset Seizures

ClinicalTrials.gov study NCT01527513. IPD Sharing: Not stated. Countries: 5. Publications: 1.

Efficacy and Safety of Eslicarbazepine Acetate (BIA 2-093) as Adjunctive Therapy for Refractory Partial Seizures

ClinicalTrials.gov study NCT00988429. IPD Sharing: Not stated. Countries: 11. Publications: 2.

Efficacy and Safety of BIA 9-1067 in Idiopathic Parkinson's Disease Patients.

ClinicalTrials.gov study NCT01227655. IPD Sharing: Not stated. Countries: 1. Publications: 1.

Efficacy and Safety of BIA 9-1067 in Idiopathic Parkinson's Disease Patients With "Wearing-off" Phenomenon

ClinicalTrials.gov study NCT01568073. IPD Sharing: Not stated. Countries: 1. Publications: 2.

opennotspecifiedOct 2019View details →

Distribution. Extent of this species' dis tribution is not yet known; recorded with certainty in Morocco, Senegal, Saudi Ara bia, and Yemen. It is thought to be con tinuously distributed from Mauritania and Senegal E to South Sudan, Ethiopia, and Eritrea. However, boundary between this species and the morphologically identical H. coffer is not known. in Family Hipposideridae (Old World Leaf-nosed Bats)

Distribution. Extent of this species' dis tribution is not yet known; recorded with certainty in Morocco, Senegal, Saudi Ara bia, and Yemen. It is thought to be con tinuously distributed from Mauritania and Senegal E to South Sudan, Ethiopia, and Eritrea. However, boundary between this species and the morphologically identical H. coffer is not known.

FIGURE 9 in Documenting diversity in the Amazonian butterfly genus Bia (Lepidoptera, Nymphalidae)

FIGURE 9. Adults in dorsal and ventral views. Taxon names appear below each set. Bia peruana: a, male, Peru, Pasco, Chuchurras (NHMUK); b, female, Peru, Pasco, Chuchurras (FLMNH); c, male, Peru, Pasco, Pachitea (MfN); d, female, Peru, Pasco, Pachitea (NHMUK); e, male, Peru, Ucayali, Pucallpa (ZSM). Intermediate between rebeli and peruana: f, male, Peru, Ucayali, Jepelacio (NHMUK).

FIGURE 12 in Documenting diversity in the Amazonian butterfly genus Bia (Lepidoptera, Nymphalidae)

FIGURE 12. Map showing collection localities of Bia species and subspecies (see Appendix). Some close localities are represented by one single dot. Dubious label data, localities that could not be accurately identified or were incomplete (e.g., Brazil, Pará) were not placed on map.

FIGURE 8 in Documenting diversity in the Amazonian butterfly genus Bia (Lepidoptera, Nymphalidae)

FIGURE 8. Adults in dorsal and ventral views. Taxon names appear below each set. Bia caelestis Penz & DeVries, new sp.: a, male holotype, Brazil, Acre, Mâncio Lima (DZUP); b, male paratype, Brazil, Amazonas, São Paulo de Olivença (MfN); c, male paratype, Brazil, Amazonas, São Paulo de Olivença (CMNH); d, female paratype, Brazil, Amazonas, São Paulo de Olivença (CMNH). Bia pucallpa Casagrande & Penz, new sp.: e, male holotype, Peru, Peru, Pasco, Rio Palcazu, Santa Rosa (MHNL). Intermediate between caelestis and actorion: f, male, Colombia, Amazonas, Puerto Nariño (LACM).

FIGURE 5 in Documenting diversity in the Amazonian butterfly genus Bia (Lepidoptera, Nymphalidae)

FIGURE 5. Adults in dorsal and ventral views. Taxon names appear below each set. Bia rebeli rebeli: a, male, Peru (USNM); b, female, Peru, Huallaga, Tingo Maria (ZSM). Bia rebeli aegina Penz & Simonsen, new ssp.: c, male holotype, Peru, Madre de Dios, Los Amigos Research Center [Puerto Maldonado] (PJD); d, female paratype, same locality (PJD); e, male, Bolivia, Santa Cruz, Buenavista (CMNH); f, female, same locality (CMNH). Intermediate between B. rebeli rebeli and B. rebeli aegina: g, male, Peru, Madre de Dios, Manu, Pakitza (USNM).

FIGURE 1. a in Documenting diversity in the Amazonian butterfly genus Bia (Lepidoptera, Nymphalidae)

FIGURE 1. a, iconotype of Bia actorion; b, lectotype of Bia peruana (SMT); c, holotype of Bia actorion rebeli (NRM); d, male and female Bia actorion showing characters used in the diagnoses (see Methods for explanation). Codes: 1—DFW white apical ocelli, 2—DFW orange band, 3—DFW iridescent band, 4—DFW androconial scales at the CuA-CuA1-CuA2 intersection, 5—DHW discal androconial pad, 6—DHW discal hairpencil, 7—VFW ripple pattern of the postmedial area.

FIGURE 3 in Documenting diversity in the Amazonian butterfly genus Bia (Lepidoptera, Nymphalidae)

FIGURE 3. Adults in dorsal and ventral views. Taxon names appear below each set. Bia actorion actorion: a, male, Guyana, Kartabo (CMNH); b, female, Guyana, Two Hat Mountain, E Kanukus S Rupununi (USNM). Bia actorion ecuatoria DeVries & Penz, new ssp.: c, male holotype, Ecuador, Sucumbios, Garza Cocha (PJD); d, female paratype, Ecuador, Sucumbios, Garza Cocha (PJD). Bia actorion occulta Casagrande & Penz, new ssp.: e, male holotype, Brazil, Pará, Acará (DZUP); f, female paratype, Brazil, Pará, Sto Antonio do Tauá (DZUP). Intermediate between actorion and decaerulea: g, male, Suriname (RMNH); h, male, Suriname, Coronie (RMNH).

FIGURE 11. Genitalia. a in Documenting diversity in the Amazonian butterfly genus Bia (Lepidoptera, Nymphalidae)

FIGURE 11. Genitalia. a, male actorion, Guyana (dissection Penz 12-01, CMNH); b, female actorion, Guyana (dissection Penz 10-02, LACM; scale bar different from male illustrations); c, male decaerulea, Lectotype, Brazil, Pará, Faro, (dissection Miller 9047, MfN); d, male rebeli, Peru, San Martín (dissection Penz 10-08, USNM); e, male caelestis, paratype, Brazil, Amazonas, São Paulo de Olivença (dissection Penz 10-29, CMNH); f, male pucallpa, Peru, Pucallpa (USUSNM 2041410); g, male peruana, Peru, Huanuco, Rio Pichis (dissection Penz 09-06, FLMNH).

FIGURE 7 in Documenting diversity in the Amazonian butterfly genus Bia (Lepidoptera, Nymphalidae)

FIGURE 7. Adults in dorsal and ventral views. Taxon names appear below each set. Bia rebeli cuprea Penz & Casagrande, new ssp.: a, male holotype Brazil, Amazonas, Borba (DZUP), note that dorsal anterior hairpencil has been removed from the left HW but that of the right HW can be seen in Fig. 10j; b, female paratype, Brazil, Amazonas, Borba (DZUP); c, male paratype, Brazil, Tapajós, Monte Christo (CMNH). Bia rebeli tapajos Penz & Simonsen, new ssp.: d, male holotype, Brazil, Pará, Belterra, Flona Tapajós (DZUP); e, male paratype, Brazil, Pará, Santarém (CMNH); f, female, Brazil, Tocantins, Ilha do Bananal (DZUP).

FIGURE 2 in Documenting diversity in the Amazonian butterfly genus Bia (Lepidoptera, Nymphalidae)

FIGURE 2. Variation in valva and gnathos morphology (lateral view) across the range of Bia, including a sample of various species and subspecies. Note intraspecific variation in series from the same locality outlined by boxes.

FIGURE 4 in Documenting diversity in the Amazonian butterfly genus Bia (Lepidoptera, Nymphalidae)

FIGURE 4. Adults in dorsal and ventral views. Taxon names appear below each set. Bia decaerulea decaerulea: a, male, Brazil, Amazonas, Manacapuru (CMNH); b, female, same locality (CMNH). Bia decaerulea cayana, Simonsen & Penz, new ssp.: c, male holotype, French Guiana, Mana River (CMNH); d, male paratype, same locality (CMNH); e, male paratype, same locality (CMNH); f, female paratype, French Guiana, Oyapok River (CMNH). Bia decaerulea pallida Casagrande & Penz, new ssp: g, male holotype, Brazil, Amazonas, Barcelos, Rio Padauari (DZUP); h, female paratype, Brazil, Amazonas, Barcelos, Rio Padauari (DZUP).

FIGURE 10 in Documenting diversity in the Amazonian butterfly genus Bia (Lepidoptera, Nymphalidae)

FIGURE 10. Androconial organs of Bia species and subspecies. Each set of images includes a detail of dorsal forewing CuA- CuA1-CuA2 intersection (image on left), dorsal hind wing discal androconial pad with associated hairpencil (center) and with the hairpencil removed (right). a, actorion actorion, Brazil, Manaus (DZUP 16588); b, actorion ecuatoria, Brazil, Mâncio Lima (DZUP 32829); c, actorion occulta, Brazil, Benevides (DZUP 22417); d, decaerulea decaerulea, Brazil, Amazonas, Nhamundá (DZUP 22356); e, decaerulea pallida, Brazil, Barcelos (DZUP 22506); f, decaerulea cayanna, French Guiana, Vidal (USNM); g, rebeli aegina, Peru, Tambopata Reserve (DZUP 22927); h, rebeli acreana, Brazil, Sta. Rosa do Purus (DZUP 22557); i, rebeli arikeme, Brazil, Ouro Preto d'Oeste (DZUP 22756); j, rebeli cuprea, Brazil, Borba (DZUP 16378); k, caelestis, Brazil, Mâncio Lima (DZUP 32830); l, pucallpa, Peru, Pucallpa. (USNM).