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Dataset results
9 results for “Bone Particles”
Quantitative results of the analysis of novel ossicle particles used in mandible bone regeneration
<p>Dataset corresponding to the results of the characterization analysis of novel holothurian ossicle biomaterials. These biomaterials were evaluated at three levels:</p> <p>1) Ex vivo analysis to determine thr potential cytotoxic effects of these biomaterials on human fibroblasts using LIVE/DEAD and quantification of DNA released to the medium.</p> <p>2) In vivo analysis to determine the potential systemic effects of these biomaterials grafted subcutaneously in laboratory rats.</p> <p>3) Histochemical and immunohistochemical analysis to determine the potential effects of these biomaterials on mandible bone regeneration.</p> <p>These results correspond to the publication entitled "<span>EVALUATION OF HOLOTHURIAN OSSICLES AS A BIOLOGICAL BIOMATERIAL FOR MANDIBULAR BONE REGENERATION</span>".</p>
Quantitative results of the analysis of two types of bone particles corresponding to the work "A comprehensive analysis of two types of xenogeneic bone particles for use in maxillofacial bone regeneration therapies"
<p>This dataset corresponds to the quantitative data generated in the work entitled "A comprehensive analysis of two types of xenogeneic bone particles for use in maxillofacial bone regeneration therapies".</p> <p>Regeneration of maxillofacial bone structures is challenging. One of the strategies applied to bone damage repair is the use of bone filler particles, and different types of these particles have been tested. In this work, we analyzed the regenerative potential of deproteinized bone particles (DP) and collagen-based bone particles (CP) to determine the potential of each biomaterial in bone repair. Results of the structural analysis using scanning electron microscopy and 3D scanning showed that DP and CP were structurally similar, and consisted of a heterogeneous mixture of bone particles of different sizes and shapes. Then, ex vivo analyses using morphological evaluation, LIVE & DEAD and quantification of DNA released to the medium demonstrated that CP and DP were highly biocompatible when used in direct and in indirect contact with human cells, at 24, 48 and 72h of follow-up. Then, when both particles were grafted for 2 months on Wistar rats in which a critical defect had been generated at the mandible bone. Results of the computed tomography analysis showed a significant reduction of the bone defect in the CP group, but not in the DP group, as compared with negative controls devoid of any bone particles. Histological analysis of the graft area revealed that both particles were biocompatible in vivo, and a regenerative tissue with collagen fibers and mineralized spots was found in CP and DP, with higher number of mineralized spots in DP. Histochemistry and immunohistochemistry analyses confirmed the presence of collagen, proteoglycans and osteocalcin at the regeneration area of CP and DP. In general, these results confirm the biocompatibility of both types of particles and that both were able to induce maxillofacial bone regeneration, especially in the case of CP. Future studies should determine their clinical usefulness in patients with cleft palate, mandibular damage and other maxillofacial applications.</p>
Maxillary Sinus Augmentation Using Different Size Bovine Bone Particles
ClinicalTrials.gov study NCT05577520. IPD Sharing: NO. Countries: 1. Publications: 13.
Bone Particles Sizes and the Stability of Soft and Hard Tissue in Aesthetic Area
ClinicalTrials.gov study NCT06020040. IPD Sharing: NO. Countries: 1. Publications: 2.
Open Maxillary Sinus Augmentation Using Different Types of Bone Particles
ClinicalTrials.gov study NCT03184857. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Bone Graft Particle Size on Bone Vitality and Volume
ClinicalTrials.gov study NCT04778709. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Influence of Bone Allograft Particle Sizes on the Quantity and Quality of New Bone Formation in Grafted Extraction Sockets and Edentulous Ridges
ClinicalTrials.gov study NCT03468998. IPD Sharing: NO. Countries: 1. Publications: 0.
The effect of whole-glucan particles on the gene expression of polarized M2 bone-derived macrophages
GEO Series GSE71814. Mus musculus. 6 samples. Type: Expression profiling by array.
The Use of CoreBone Coral Particles vs. Cones for Preservation of Alveolar Bone
ClinicalTrials.gov study NCT02632734. IPD Sharing: Not stated. Countries: 0. Publications: 0.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.