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249 results for “Braces”
Dataset from Experimental and Nonlinear Finite Element Modeling Investigating an Innovative Buckling Restrained Bracing System for Rehabilitation of Seismic Deficient Structures
<p>The data presented in this paper were collected experimentally and modeled using the finite element method. A total of six BRBs (i.e., duplicates of three types of BRB core bars) specimens were tested experimentally and verified numerically using the finite element method employing the commercial Software ABAQUS. Specific labeling was used to designate each BRB type. Three core bars were used in the tested BRBs: fully-threaded, threaded-notched, and smooth-shaved. The specimens are labeled according to their core bar type and diameter. i.e., BRB-12-Th stands for a full threaded core bar diameter of 12 mm, the threaded notched type was labeled BRB-12-Th-Nd, and the smooth shave one was labeled BRB-12-Sh.</p> <p>Further details of the tested BRBs are included in the excel file called dimensions and properties of BRBs. The worksheet provides details of the BRB components (i.e., core bar, restraining unit, and innovative end units). The dimensions and strength of the materials were obtained from coupon tests. The experimental data are presented in the second excel file labeled hysteresis with three embedded worksheets, one for each type of BRB. The excel sheets provide the cyclic loading data and plots showing the hysteresis behavior of tested BRBs. A sample of the loading protocol included in the second excel file is presented in Fig.1. The third excel file presents the analytical data extracted from experimental data that has two sheets: stiffness and energy dissipation. The sheet labeled stiffness has the secant stiffness versus deformation plot for the push-pull cycles (compression-tension). The second sheet labeled energy dissipation shows the cumulative energy dissipated.</p>
A Dataset for Inertial Measurements of Scoliotic Patients during Timed-Up and Go Tests in Unbraced and Braced Scenarios
<p>Repository composition:</p> <p>*** Dataset ***</p> <p>Anonymous data pertaining to each participant is stored in a single folder, named S##. </p> <p>Each of these folders contains the following:</p> <p>1) Raw IMU data from the G-Walk sensor (3-axis acceleration, 3-axis gyroscope, 3-axis magnetometer) recorded during the Timed-Up and Go tests in .txt files. Specifically, the 3 experimental conditions are "Unbraced", "Conventional" and "3DPrinted". Each condition was recorded three times (01, 02, 03).</p> <p>2) A .xlsx file named "TUG_Metrics" with the values of the TUG metrics for each condition.</p> <p>3) A .xlsx file named "Segmentation_Times" with the start and end timepoints of the TUG phases for each condition.</p> <p>*** Boxplot ***</p> <p>This is a folder containing boxplots in .png files for each TUG metric, comparing the three experimental conditions.</p> <p>*** Histogram ***</p> <p>This is a folder containing histograms in .png files for each TUG metric, comparing the three experimental conditions.</p> <p>*** QQ Plot ***</p> <p>This is a folder containing qq-plots in .png files for each TUG metric, comparing the three experimental conditions.</p>
ATP synthase evolution on a cross-braced dated tree of life
<p><strong>Abstract</strong></p><p>The timing of early cellular evolution, from the divergence of Archaea and Bacteria to the origin of eukaryotes, is poorly constrained. The ATP synthase complex is thought to have originated prior to the Last Universal Common Ancestor (LUCA) and analyses of ATP synthase genes, together with ribosomes, have played a key role in inferring and rooting the tree of life. We reconstruct the evolutionary history of ATP synthases using an expanded taxon sampling set and develop a phylogenetic cross-bracing approach, constraining equivalent speciation nodes to be contemporaneous, based on the phylogenetic imprint of endosymbioses and ancient gene duplications. This approach results in a highly resolved, dated species tree and establishes an absolute timeline for ATP synthase evolution. Our analyses show that the divergence of ATP synthase into F- and A/V-type lineages was a very early event in cellular evolution dating back to more than 4Ga, potentially predating the diversification of Archaea and Bacteria. Our cross-braced, dated tree of life also provides insight into more recent evolutionary transitions including eukaryogenesis, showing that the eukaryotic nuclear and mitochondrial lineages diverged from their closest archaeal (2.67-2.19Ga) and bacterial (2.58-2.12Ga) relatives at approximately the same time, with a slightly longer nuclear stem-lineage.</p><p><strong>Repository Contents</strong></p><p><strong>1_100Eukaryote_genomes.tar.gz</strong>: includes all protein sequence files for the 100 Eukaryotes sampled in this study. </p><p><strong>2_Phylogenies.tar.gz</strong>: includes all files used for phylogenetic analyses. Folders are organized as follows: </p><ul><li><strong>1_ATPsynthase_gene_trees</strong>: this folder contains all sequence, alignment, and tree files for the ATP synthase gene trees. Files are organized as follows and are associated with the corresponding parts of the manuscript: Figure 3, Figure 5B, Supplementary Figures 5-10, Supplementary Figures 18-19<ul><li>Folder '1_sequences' includes all unaligned fasta sequence files for each ATP synthase gene tree (see Methods)</li><li>Folder '2_alignments' includes all alignments generated using MAFFT L-INS-i (subdirectory: 1_untrimmed) and trimmed with BMGE (subdirectory: 2_trimmed)</li><li>Folder '3_treefiles' includes all IQ-TREE2 output files for all ATP synthase gene phylogenies. Any files with suffix *taxa.treefile contain the full taxonomic string for each accession. </li><li>Folder '4_pdfs' includes PDF files for each ATP synthase gene tree</li></ul></li><li><strong>2_Eukaryotic_subsets</strong>: this folder contains all sequence, alignment, and tree files for ATP synthase Eukaryotic subset gene trees. Files are organized as follows and are associated with the corresponding parts of the manuscript: Supplementary Figure 11 <ul><li>Folder '1_sequences' includes all unaligned fasta sequence files for the eukaryotic subsets.</li><li>Folder '2_alignments' includes all alignments generated using MAFFT L-INS-i (subdirectory: 1_untrimmed) and trimmed with BMGE (subdirectory: 2_trimmed).</li><li>Folder '3_treefiles' includes all Bayesian trees inferred for eukaryotic subsets.</li><li>Folder '4_pdfs' includes PDF files for each eukaryotic subset tree </li></ul></li><li><strong>3_21eLife_concatenated_species_tree</strong>: this folder contains all sequence, alignment, and tree files for the single gene tree and concatenated phylogeny analyses (inferred using 21 single-copy marker genes, see Methods). Files are organized as follows and are associated with the following parts of the manuscript: Figure 1, Supplementary Figure 20 <ul><li>Folder '1_inspection_start' corresponds to the initial manual inspection of the single gene trees and includes the following subdirectories:<ul><li>Folder '1_sequences' includes all protein sequence fasta files corresponding to the 27 original single-copy marker genes</li><li>Folder '2_alignments' includes all alignment files generated using MAFFT L-INS-i (subdirectory: 1_untrimmed) and trimmed with BMGE (subdirectory: 2_untrimmed)</li><li>Folder '3_treefiles' includes all IQ-TREE2 output files for all phylogenies (27 single-copy marker genes)</li><li>Folder '4_pdfs' includes PDF files for each single gene tree</li></ul></li><li>Folder '2_inspection_final' corresponds to the final manual inspection of the single gene trees and includes the following subdirectories:<ul><li>Folder '1_sequences' includes all protein sequence fasta files corresponding to the final 21 single-copy marker genes</li><li>Folder '2_alignments' includes all alignment files generated using MAFFT L-INS-i (subdirectory: 1_untrimmed) and trimmed with BMGE (subdirectory: 2_untrimmed)</li><li>Folder '3_treefiles' includes all IQ-TREE2 output files for all phylogenies (21 single-copy marker genes)</li><li>Folder '4_pdfs' includes PDF files for each single gene tree</li></ul></li><li>Folder '3_concatenated_phylogeny' contains concatenated alignment generated from the final 21 single-copy marker gene alignments<ul><li>Folder '1_alignment' includes the concatenated alignment generated from the 21 trimmed alignments from the final inspection</li><li>Folder '2_treefiles' includes all IQ-TREE2 output files for trees inferred using the two different models (subdirectories: LG+C20+R+F and LG+C60+R+F)</li></ul></li><li>Folder '4_Eukaryote_only_phylogeny' contains sequence, alignment, and tree files for 21 single-copy marker genes used to infer a Eukaryote-only phylogeny. Folder is organized as follows and files correspond to Supplementary Figure 3: <ul><li>Folder '1_sequences' includes all protein sequence fasta files corresponding to the 21 single-copy marker genes with only Eukaryotes</li><li>Folder '2_alignments' includes all alignment files generated using MAFFT L-INS-i (subdirectory: 1_untrimmed) and trimmed with BMGE (subdirectory: 2_untrimmed)</li><li>Folder '3_concatenated_phylogeny' includes concatenated alignment generated from 21 single-copy markers with only Eukaryotes (subdirectory: 1_alignment) and all IQ-TREE2 output files for the concatenated phylogeny (subdirectory: 2_treefiles)</li><li>Folder '4_pdfs' includes PDF files for the concatenated Eukaryote tree</li></ul></li></ul></li><li><strong>4_Ribosomal_species_tree</strong>: this folder contains all sequence, alignment, and tree files for the single gene tree and concatenated phylogeny analyses (inferred using 12 ribosomal marker genes, see Methods). Files are organized as follows and are associated with the corresponding parts of the manuscript: Figure 5A, Figure 5C, Supplementary Figures 12-16, Supplementary Figure 21<ul><li>Folder '1_sequences' includes all protein sequence fasta files for the original 15 ribosomal proteins. Sequence sets include the best-hit Archaea and Bacteria, and nuclear, mitochondrial, and plastid eukaryotic homologs</li><li>Folder '2_alignments' includes all alignment files generated using MAFFT L-INS-i (subdirectory: 1_untrimmed) and trimmed with TRIMAL (gappy-out) (subdirectory: 2_trimmed)</li><li>Folder '3_treefiles' includes all original FastTree tree files, tree files with highlighted sequences to remove (*blue-to-rem = eukaryotic nuclear homolog only; *colored-to-rem = eukaryotic nuclear, mitochondrial, and plastid homologs). PDFs of each marker gene tree are also included that depict highlighting of sequences to keep and/or remove. </li><li>Folder '4_concatenated_phylogeny' contains concatenated alignment generated from the final 12 ribosomal marker genes<ul><li>Folder '1_alignment' includes the concatenated alignment generated with 12 ribosomal marker proteins in MAFFT L-INS-i and trimmed with TRIMAL (gappy-out)</li><li>Folder '2_phylogeny' includes all IQ-TREE2 output files for the species tree inferred using the LG+C60+R+F model</li></ul></li></ul></li><li><strong>5_Dating_analysis</strong>: includes all Mcmcdate output files for the dating analyses (species tree and ATP synthase gene tree, see Methods). <ul><li>Folder '0_Starting_species_phylogenies' includes the treefiles (with and without taxonomic string) for the Edited1 and Edited2 topologies that were used in the dating analyses (see Methods). </li><li>Folder '1_Edited1_dating' includes all dated tree files and monitor files for braced and unbraced analyses of the Edited1 species tree topology. Data corresponds to Supplementary Figure 12, Supplementary Figure 14-15 </li><li>Folder '2_Edited2_dating' includes all dated tree files and monitor files for braced and unbraced analyses of the Edited2 (focal) species tree topology. Data corresponds to Figure 5A, Figure 5C, Supplementary Figure 13, Supplementary Figure 16.</li><li>Folder '3_ATP_synthase_dating' includes all dated tree files and monitor files for braced and unbraced analyses of the ATP synthase gene tree. Data corresponds to Figure 5B, Supplementary Figures 18-19.</li></ul></li></ul><p><strong>3_Scripts.tar.gz</strong>: includes all workflows and scripts used for phylogenetic analyses. </p><ul><li><strong>1_workflows</strong>: includes bash workflows for phylogenetic analyses (details on software versions are included in each workflow summary): <ul><li>Workflow_ATPsynthase_gene_trees.sh: generation of the ATP synthase phylogenies</li><li>Workflow_21eLife_marker_phylogeny.sh: inferring the 21 marker-gene species tree </li><li>Workflow_Ribosomal_species_tree.sh: inferring the 12 ribosomal marker-gene species tree </li><li>Workflow_Database_annotations.sh: workflow for gene annotation for 800 sampled Archaea, Bacteria, and Eukaryota</li></ul></li><li><strong>2_R_scripts</strong>: includes R scripts used for the Eukaryote sequence contamination screening (Figure 1, Figure 2, Supplementary Figure 2, Supplementary Figures 4, 5, 8-10), presence-absence analyses (Figure 1, Figure 2, Supplementary Figure 2), and plotting tree figures (Supplementary Figures 4-10). Input mapping files and R output files are included.<ul><li>Folder '1_Euk_contamination_screen' contains workflow 'Eukaryote_contamination_screen.Rmd' used to inspect Eukaryotic ATP synthase sequences for bacterial contamination</li><li>Folder '2_Presence_absence' includes sub-directories:<ul><li>Folder '1_Species_tree' includes the treefile(s) used for ordering the plots in Figure 1 and Supplementary Figure 2 ('1_tree'), the taxonomic and COG mapping files and the list of putative contamination to remove ('2_input_files'), the raw count table for all 800 taxa ('3_Output_files'), R output plot(s) ('4_Plotting'), and the script to generate presence-absence plots 'Presence-absence.R'. </li><li>Folder '2_Eukaryotes_only' includes organelle information, protein mapping files, taxonomic mapping files, and list of putative contamination to remove ('1_Input_files'); raw count table of ATP synthase subunits ('2_Output_files'); and R output plots ('3_Output_files').<br><i>Please see 'Eukaryote_contamination_screen.Rmd' in parent directory '2_R_scripts' for more information on how Eukaryotic sequences were screened, how the list of contaminating sequences was curated, and how the plot for Figure 2 was generated. </i></li></ul></li><li>Folder '3_Plotting_trees' includes the rectangular and radial trees generated for each ATP synthase trees (see Supplementary Figures 5-10). Trees were generated from the treefiles for the ATP synthase gene trees (see above), and script 'Plotting_trees.Rmd'</li><li>'Marker_gene_counts.R' script used to count marker genes per genome (see Methods)</li></ul></li><li><strong>3_TimeTree</strong>: includes python scripts used to generate the time-trees (Figure 5C, Supplementary Figures 15 and 19)</li><li><strong>4_ALE_workflow</strong>:<strong> </strong>example bash workflow used to run ALE. For details see Methods. </li></ul>
Evaluation of a Novel Semi-Rigid Brace for Adolescent Idiopathic Scoliosis
ClinicalTrials.gov study NCT07040150. IPD Sharing: NO. Countries: 1. Publications: 2.
Protonics Knee Brace Versus Hamstring Resisted Exercise (HRE) on Individuals With Patellofemoral Pain Syndrome
ClinicalTrials.gov study NCT03042559. IPD Sharing: NO. Countries: 1. Publications: 7.
Knee Bracing for People With Patellofemoral Osteoarthritis
ClinicalTrials.gov study NCT00381563. IPD Sharing: NO. Countries: 1. Publications: 1.
Bracing in Adolescent Idiopathic Scoliosis Trial (BrAIST)
ClinicalTrials.gov study NCT00448448. IPD Sharing: Not stated. Countries: 2. Publications: 6.
Enhancing the Therapeutic Effect of Bracing for Adolescent Idiopathic Scoliosis With a Hybrid Bracing Protocol
ClinicalTrials.gov study NCT07045337. IPD Sharing: NO. Countries: 1. Publications: 0.
Outcomes of Compliance With Brace Wear in Clubfoot
ClinicalTrials.gov study NCT01481324. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Thromboembolic Risk Stratification by TRiP(Cast) Score to Guide Physicians in Preventive Treatment Prescriptions for Patients With Lower Limb Trauma Requiring Brace or castING.
ClinicalTrials.gov study NCT04064489. IPD Sharing: NO. Countries: 2. Publications: 2.
Developmental Dysplasia of the Hip: Observation vs. Bracing
ClinicalTrials.gov study NCT05869851. IPD Sharing: NO. Countries: 1. Publications: 1.
Use of the DJO Brace With the Motion Intelligence Platform in the Postoperative Total Knee Arthroplasty Patient
ClinicalTrials.gov study NCT04655703. IPD Sharing: NO. Countries: 1. Publications: 1.
Efficacy Study of an Unloading Brace for Knee Osteoarthritis
ClinicalTrials.gov study NCT02150057. IPD Sharing: NO. Countries: 1. Publications: 17.
Comparison Between Protraction Facemask and Upper Braces for Underbite Correction in Growing Children
ClinicalTrials.gov study NCT06759896. IPD Sharing: NO. Countries: 1. Publications: 1.
Brace Versus Casting in Pediatric Low Risk Ankle Fractures
ClinicalTrials.gov study NCT00132964. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Clinical Trial Comparing C-Brace to Knee Ankle Foot Orthosis (KAFO)/Stance Control Orthosis (SCO)
ClinicalTrials.gov study NCT03906656. IPD Sharing: NO. Countries: 4. Publications: 0.
Postoperative Hip Bracing After Hip Arthroscopy
ClinicalTrials.gov study NCT04599296. IPD Sharing: NO. Countries: 1. Publications: 12.
Bracing and Strengthening for Posterior Tibial Tendon Dysfunction
ClinicalTrials.gov study NCT00756457. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Duration of Brace Wear in Clubfoot Treatment - A Prospective Randomized Trial
ClinicalTrials.gov study NCT01551264. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Cast Iron Bracings on Victorian Railway Bridge
Source: Objaverse 1.0 / Sketchfab
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