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23 results for “Breach”
Accompanying dataset for: "Flow and detailed 3D morphodynamic data from laboratory experiments of fluvial dike breaching"
<p>This dataset accompanies the manuscrpit "Flow and detailed 3D morphodynamic data from laboratory experiments of fluvial dike breaching" submitted to Scientific Data.</p>
Vector sequences in early WIV SRA sequencing data of SARS-CoV-2 inform on a potential large-scale security breach at the beginning of the COVID-19 pandemic
<p>DESCRIPTION</p> <p>Sequences identified as Influenza A virus, Spodoptera frugiperda rhabdovirus and Nipah henipavirus have been previously identified within the early HiSeq 1000 and HiSeq 3000 sequencing data of SARS-CoV-2, SRR11092059,SRR11092060,SRR11092061 and SRR11092062, and were being used to support the hypothesis that a "simultaneous outbreak of multiple zoonotic viruses" have happened in the Huanan Seafood market. https://doi.org/10.31219/osf.io/s4td6</p> <p>However, a closer examination of these sequences revealed that they were not sequences of actual wild viruses, but were in stead fragments left behind from PCR products and cloning vectors harboring both cDNA clones and infectious clones of such viruses, with evidence of viral sequences being joined directly to DNA sequences of vector and non-human origin within the same short reads.</p> <p>Here are the vector sequences and PCR product-like sequences recovered from the earliest WIV SRA sequencing data of Human SARS-CoV-2 from dataset SRR11092059,SRR11092060,SRR11092061,SRR11092062.</p> <p>Sequences associated with Vectors and PCR products from 3 distinct viral species have been obtained: The 3'-end of a Nipah Henipahvirus with fusion to a Hepatitis D virus Ribozyme, a T7 terminator and a Tetracycline resistance gene, The 5'-end of the same Nipah Henipahvirus with fusion to sequences found in diverse vectors, A complete vector genome encoding the HA gene of Influenza A virus subtype H7N9 under a CMV promoter and a bgH polyA terminator, and 221 Contiguous sequences corresponding to the Spodoptera frugiperda rhabdovirus reference genome fused to sequences that were homologous to multiple Plastid sequences and Notably Mitochondrial sequences of Rodents.</p> <p>As sequences corresponding to a rescued infectious clone of a BSL-4 organism (Nipah Henipahvirus) were found in sample sequences that supposedy represents patient samples that were obtained from Hospital ICU and sequenced in a pathogen diagnosis laboratory (which is separate from the Virology Research laboratory which is implied by the context of an Infectious Clone of such an organism, evident by the 3'-HDV ribozyme and T7 terminator fused directly to the 3'-terminus of the Nipah Henipahvirus reads), The discovery of artifact-containing sequences of at least 3 different pathogen species that are phylogenetically and methodologically distinct from each other in samples that were supposedly submitted by a laboratory that is Separate from the virological research laboratories that could have hosted such clone sequences imply extensive crosstalk and cross-contamination between the various laboratories within the Wuhan Institute of Virology, which includes at least one BSL-4 laboratory with evidence of containment breach of a BSL-4 organism and it's subsequent introduction into RNA-seq samples that were processed by a laboratory of distinct and separate purposes than the basic virological research evidenced by the Infectious Clone of the Hipah Henipahvirus.</p> <p>Such a discovery therefore likely imply a major security breach happening within the Wuhan institute of Virology at the time when the first sequences of SARS-CoV-2 was sampled and sequenced, which have important implications on the origins of the SARS-CoV-2 virus itself.</p> <p>METHODS</p> <p>The metagenomic sequencing datasets, SRR11092059,SRR11092060,SRR11092061 and SRR11092062 were first analyzed using the NCBI phylogenetic analysis tool, which identified viral sequences that is not related to SARS-CoV-2 itself. These include Influenza A virus (IAV, subtype H7N9), Spodoptera frugiperda rhabdovirus and Nipah Henipahvirus.</p> <p>The datasets were then subjected to BLAST search using MEGABLAST against the reference sequences of such viruses to verify the existence of the viral sequences and determine the exact sybtype of such viruses and the closest sequences on GenBank that corresponds to the reads. There seuqences are MH926031.1 for the Spodoptera frugiperda rhabdovirus, KY199425.1 for the Influenza A virus and AY988601.1 for the Nipah Henipahvirus.</p> <p>A second round BLAST analysis with these identified sequences were then performed, which unexpectedly revealed numerous reads corresponding to Cloning vectors and non-human Mitochondrial and Plastid sequences being fused directly to the sequences of the identified viral species. Reads were then downloaded and subjected to assembly using the CAP3 sequence assembly program and the EGASSEMBLER tool. Contig sequences were then queried against the NCBI nr/nt database which unanimously identified the original sample sequences as viral sequences inserted into cloning vectors.</p> <p>The complete sequence of the Influenza A virus Haemagluttinin (HA) gene clone was obtained from SRR11092061,SRR11092062 using multiple rounds of BLAST search and sequence assembly expansion on the existing vector-virus junction contigs, and a partial sequence corresponding the 3'-end of Nipah Henipahvirus AY988601.1 fused to a 3'-HDV ribozyme, T7 terminator and a Tet resistance gene was obtained from SRR11092059. In addition, 221 Contig sequences corresponding to the Rhabdovirus MH926031.1 fused to Chloroplast sequence MN524635.1 and Rodent Mitochondrial sequence MT241668.1 have been recovered from SRR11092061.</p> <p>We then performed a BLAST search using the identified vector sequences on SRR11092059,SRR11092060,SRR11092061 and SRR11092062, which confirms the existence of these two vetor sequences in all 4 datasets.</p>
Dune Overwash and Breaching data set produced at the CIEM flume, Hydralab III
<p>The data set here presented helps to to improve the understanding of dune overwash and breaching processes during storm surges in nearly prototype scale. The experiments were done at the CIEM wave flume at UPC, Barcelona, as part of Hydralab III. The large scale movable-bed hydraulic experiments measure hydrodynamics and sediment processes involved in onshore and offshore sediment transport, dune breaching and overwash.</p> <p>Due to its size, the data set can not be placed on this repository and will be provided on demand. Please contact with the authors or with the data manager of the CIEM installation.</p> <p>More information can be found on the published papers:</p> <p>D'Alessandro, F.; Tomasicchio, R.; Alsina, J.; Caceres, I.; Fortes, C.J.E.M.; Ilic, S.; James, M.; Nagler, L.; Pinheiro, L.V.; Sanchez-Arcilla, A.; Sancho, F.; Shaw, E.; Schüttrumpf, H., 2010. Dune over wash and breaching, Coastlab 2010, Barcelona, Spain.</p> <p> </p>
Data for: How natural foreshores offer flood protection during dike breaches: An explorative flume study
<p>Data from an explorative flume study on dike breaches with foreshores. </p><p>1. Data from pressure sensors to obtain water depths at three locations within the flume.<br>2. Images from video material to analyse top view flume. </p><p>The data is described in the following publication:<br>van den Hoven, K., J. van Belzen, M.G. Kleinhans. D.M.J. Schot, J. Merry, J.M. van Loon-Steensma, T.J. Bouma. How natural foreshores offer flood protection during dike breaches: An explorative flume study. Estuarine, Coastal and Shelf Science 108560. https://doi.org/10.1016/j.ecss.2023.108560</p>
Data for One Earth publication "Breaching planetary boundaries: Over half of global land area suffers critical losses in functional biosphere integrity"
<p>This repository contains data and processing scripts for the study: Stenzel et al. 2025, One Earth, "Breaching planetary boundaries: Over half of global land area suffers critical losses in functional biosphere integrity".</p>
Mechanisms of the Non-uniform Breach Morphology Evolution of Landslide Dams Composed of Unconsolidated Sediments During Overtopping Failure
<p>Data that can be used to replicate and validate the results presented here are available through the upload file.</p> <p>Data access will be available upon request prior to official publication of this work.</p>
Supplementary data for "Quantifying the Impact Factors of Landslide Dam Breaching: A Numerical Study on the Influence of Lake Geometry and Upstream Inflow"
<p>The supplementary data provides a summary of previously published data and natural case studies related to landslide dam breaching, which were utilized in the study titled <em>"Quantifying the Impact Factors of Landslide Dam Breaching: A Numerical Study on the Influence of Lake Geometry and Upstream Inflow."</em></p>
Dataset, setups and scripts to numerically reproduce the breaching process
<p>This dataset is part of the article: Numerical investigation of mode failures in submerged granular columns - E. P. Montellà, J. Chauchat, C. Bonamy, D. Weij, G. H. Keetels and T. J. Hsu.</p> <p>This file contains the numerical results obtained with SedFoam to model the breaching experiments of Weij (2020) (full thesis available at https://pure.tudelft.nl/ws/portalfiles/portal/84166231/2020_03_05_thesis_dweij.pdf ).</p> <p>The folder and files are set to reproduce the Experiments 8 and 16 in case the user wants to re-launch the numerical simulations. These simulations can be executed with ./Allrun.</p> <p>Two Python scripts are available for post-processing. The Python scripts require the fluidfoam package to be installed and it is freely available at https://github.com/fluiddyn/fluidfoam .</p> <p> </p>
Data from: Health IT, hacking, and cybersecurity: national trends in data breaches of protected health information
Objective: The rapid adoption of health information technology (IT) coupled with growing reports of ransomware, and hacking has made cybersecurity a priority in health care. This study leverages federal data in order to better understand current cybersecurity threats in the context of health IT. Materials and Methods: Retrospective observational study of all available reported data breaches in the United States from 2013 to 2017, downloaded from a publicly available federal regulatory database. Results: There were 1512 data breaches affecting 154 415 257 patient records from a heterogeneous distribution of covered entities (P < .001). There were 128 electronic medical record-related breaches of 4 867 920 patient records, while 363 hacking incidents affected 130 702 378 records. Discussion and Conclusion: Despite making up less than 25% of all breaches, hacking was responsible for nearly 85% of all affected patient records. As medicine becomes increasingly interconnected and informatics-driven, significant improvements to cybersecurity must be made so our health IT infrastructure is simultaneously effective, safe, and secure.
THE DIFFERENCE BETWEEN THE CRIME OF FRAUD AND THE CRIME OF PROPERTY DAMAGE BY DECEPTION OR BREACH OF TRUST
Open the record for dataset details and reuse information.
Impact of dam height and grain size distribution on breaching of non-cohesive dams due to overtopping
<div> <p>The National Inventory of Dams reports 74,400 earthen dams in the United States in 2021; of these dams, approximately 27% are considered at high or significant hazard risk, that is dam failure will cause widespread damage and loss of lives. The most frequent cause of dam failure is breaching caused by overtopping. Accurate predictions of breach evolution are thus crucial to determine flood hydrographs for the safety of communities and properties at risk. Laboratory experiments were conducted on non-cohesive, compacted embankments to understand the role of dam height and sediment grain size on breaching caused by overtopping. Dam heights varied from 10 cm to 45 cm. Model structures were built with fine sand or with a mixture of fine sand and silt. Experiments showed that increasing dam height increases peak discharge. The presence of silt in model embankment material, on the contrary, lowers peak discharge and makes failure longer. In sand dams, sediment deposition on the downstream face becomes important as dam height increases. This deposition reduces incision rate of the breach channel, delaying time to peak and rapid channel widening. In all embankments, breach evolution was gradual until erosion of the breach channel reached the reservoir. Throughout the experiment, bank failure caused gradual widening of the breach channel. In presence of silt, no sediment deposition occurred on the downstream face, and time to peak increased with dam height because upstream migrating erosional waves formed in the breach channel, and the time for these waves to reach the reservoir increased with dam height. Breach channel widening associated with bank failure is practically non-existent until peak discharge is reached, then sudden widening caused by major failures occurs. Overall, breach width decreases with an increase in silt content.</p> </div>
MMG vs. EMG for Cortical Breach Detection
ClinicalTrials.gov study NCT05352048. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Health IT, hacking, and cybersecurity: national trends in data breaches of protected health information
Open the record for dataset details and reuse information.
Data from: Adaptation in temporally variable environments: stickleback armor in periodically breaching bar-built estuaries
Open the record for dataset details and reuse information.
Impact of dam height and grain size distribution on breaching of non-cohesive dams due to overtopping
Open the record for dataset details and reuse information.
Breaching self-tolerance to Alu duplex RNA underlies MDA5-mediated inflammation [WT HEK293T and mutant MDA5]
GEO Series GSE103539. Homo sapiens. 5 samples. Type: Other.
DNA Methylation Patterns of Chronic Explosive Breaching in U.S. Military Warfighters
GEO Series GSE155426. Homo sapiens. 89 samples. Type: Methylation profiling by genome tiling array.
Breaching self-tolerance to Alu duplex RNA underlies MDA5-mediated inflammation
GEO Series GSE104865. Homo sapiens. 9 samples. Type: Other.
Breaching self-tolerance to Alu duplex RNA underlies MDA5-mediated inflammation [ADAR1KO HEK293T and WT MDA5]
GEO Series GSE104864. Homo sapiens. 4 samples. Type: Other.
Сhurch at the breach, Pskov, Russia
**Church of the Intercession and Nativity of the Virgin at the breach** is a UNESCO World Cultural Heritage Site - 15-16 century chirch in Pskov, Russia. The breach is a breach made by Stephen Batory during his unsuccessful storming the city in 1582. [Wikipedia page (Russian)](https://ru.wikipedia.org/wiki/Церковь_Покрова_и_Рождества_от_Пролома_(Псков)) | [Location](https://goo.gl/maps/EeQgvj876y2nYa9z7) | [Panorama](https://goo.gl/maps/Bv38j5SxpRei5s578) Captured in June 2021 **Церковь Покрова и Рождества Богородицы от Пролома** - церковь XV—XVI веков во Пскове, является объектом всемирного культурного наследия ЮНЕСКО. Находится в южном углу Окольного города у Покровской башни. Пролом — место обрушения крепостной стены во время неудачного штурма Пскова Стефаном Баторием в 1582 году. [Страница в Википедии](https://ru.wikipedia.org/wiki/Церковь_Покрова_и_Рождества_от_Пролома_(Псков)) | [Местоположение](https://yandex.ru/maps/-/CCUmbGsHcD) | [Панорама](https://yandex.ru/maps/-/CCUmbKA58A) Снято в июне 2021 Source: Objaverse 1.0 / Sketchfab
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.