Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
23
datasets available to search
ShareScore release 0.9.0
Dataset results
23 results for “Brucella abortus”
Dataset - Antibiotic persistence of intracellular Brucella abortus
<p>Dataset for the manuscript "Antibiotic persistence of intracellular <em>Brucella abortus</em>" published at PLoS Neglected Tropical Diseases, July 2022. ( <a href="https://doi.org/10.1371/journal.pntd.0010635">https://doi.org/10.1371/journal.pntd.0010635</a>).</p> <p>Data corresponding to each main figure are in separate .zip folders. Metadata compiled in a separated file.</p>
................................................................................................................................................. Fig. 5. Phylogenetic tree based on 16S rRNA sequences (a) and gltA sequences (b) showing the position of strains R1T, R3, R4 and R6 in relation to the known Bartonella spp. The tree was rooted by using Brucella abortus (a) and Sinorhizobium meliloti (b) as the outgroup. in Bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer.
................................................................................................................................................. Fig. 5. Phylogenetic tree based on 16S rRNA sequences (a) and gltA sequences (b) showing the position of strains R1T, R3, R4 and R6 in relation to the known Bartonella spp. The tree was rooted by using Brucella abortus (a) and Sinorhizobium meliloti (b) as the outgroup.
Bovine trophoblasts: control vs. infected with Brucella abortus
GEO Series GSE10342. Bos taurus. 3 samples. Type: Expression profiling by array.
GcrA binding pattern to Brucella abortus genome
GEO Series GSE136733. Brucella abortus. 1 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Transcriptome analysis of Brucella abortus S19∆per (a perosaminesynthetase gene mutant of strain S19) immunized mice spleen revealed activation of MHC-I and MHC-II pathways
GEO Series GSE121040. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Microarray analysis to identify differentially expressed genes of intracellular Brucella abortus in RAW264.7 cells
GEO Series GSE46459. Brucella abortus str. 2308 A; Brucella abortus bv. 1 str. 9-941. 6 samples. Type: Expression profiling by array.
The Brucella abortus virulence regulator, LovhK, is a sensor kinase in the general stress response signaling pathway
GEO Series GSE59513. Brucella melitensis. 6 samples. Type: Expression profiling by high throughput sequencing.
The endoribonuclease YbeY is linked to proper cellular morphology and virulence in Brucella abortus
GEO Series GSE113222. Brucella abortus. 4 samples. Type: Expression profiling by array.
Gene expression profiling of Brucella abortus-infected mouse macrophages
GEO Series GSE96071. Mus musculus. 6 samples. Type: Expression profiling by array.
Expression Data from Brucella abortus strain 2308 and isogenic mucR mutant cells
GEO Series GSE40532. Brucella abortus. 4 samples. Type: Expression profiling by array.
RAW264.7 macrophages infected with Brucella abortus, B. melitensis, B. neotomae, and B. ovis
GEO Series GSE8403. Mus musculus. 16 samples. Type: Expression profiling by SAGE.
Global gene transcriptional profiles of RAW 264.7 cells following the infection with Brucella abortus wild and mutant strains
GEO Series GSE79264. Mus musculus. 26 samples. Type: Expression profiling by array.
Microarray Analysis of mRNA Levels from RAW264.7 Macrophages Infected with Brucella abortus
GEO Series GSE8384. Mus musculus. 5 samples. Type: Expression profiling by array.
Genome analysis of gene expression by THP-1 macrophage during Brucella abortus wild type and mutant strains infection
GEO Series GSE102260. Homo sapiens. 5 samples. Type: Expression profiling by array.
Transcriptional profile of bovine chorioallantoic membrane explants in response to wild type, ΔvirB2 or ΔbtpB Brucella abortus
GEO Series GSE58216. Bos taurus. 16 samples. Type: Expression profiling by array.
RNA-seq based transcriptinal profiling of intracellular Brucella abortus and Brucella abortus-infected murine macrophages
GEO Series GSE100914. Mus musculus; Brucella abortus 544. 4 samples. Type: Expression profiling by high throughput sequencing.
RNase and sRNA activity in Brucella abortus
GEO Series GSE155009. Brucella abortus. 11 samples. Type: Expression profiling by high throughput sequencing.
Comparison of CcrM-dependent methylation in Caulobacter crescentus and Brucella abortus by nanopore sequencing
GEO Series GSE260848. Brucella abortus 2308; Caulobacter vibrioides NA1000. 10 samples. Type: Methylation profiling by high throughput sequencing.
Phenotypes controlled by the Brucella abortus two component system BvrR/BvrS differ in their dependence on the phosphorylation of the response regulator BvrR
<p><em>Brucella abortus</em> is a zoonotic pathogen whose ability to survive intracellularly at the endoplasmic reticulum is essential for its virulence. The two-component system BvrR/BvrS is essential for intracellular survival due to the transcriptional control of the type IV secretion system VirB and its transcriptional regulator VjbR. In addition, this system is a master regulator of several traits including membrane conformation by controlling proteins such as Omp25. To understand the regulatory strategies used by BvrR we generated dominant positive and negative versions of this response regulator which, in addition to the wild type version, were introduced in a BvrR- background. We then characterized BvrRS-controlled phenotypes and the expression of proteins controlled by the system. We found two regulatory patterns exerted by BvrR. The first pattern was represented by resistance to polymyxin and expression of Omp25 (membrane conformation) which were restored to normal levels by the dominant positive and the wild type version, but not the dominant negative version, of BvrR. The second pattern was represented by intracellular survival and expression of VjbR and VirB (virulence) which were, again, fully complemented by wild type and the dominant versions of BvrR but, significantly restored by complementation with the dominant negative version of the response regulator. These results suggested a differential binding of unphosphorylated BvrR with promoters of the genes it controls. We confirmed this hypothesis by showing that the dominant negative version of BvrR was not able to interact with the promoter of <em>omp25</em> but was able to interact with the promoter of <em>vjbR</em>. Furthermore, a global transcriptional analysis indicated that some genes respond to the presence of the dominant negative version of BvrR. Thus, BvrR possesses diverse strategies to exert transcriptional control on the genes it regulates and as consequence on the phenotypes controlled by this response regulator.</p> <p>Here, we include the raw count data (rawcounts.txt) for all analyzed samples, as well as the experimental designed used to perform the statistical results (target.txt).</p>
Expression Data from Brucella abortus strain 2308 and isogenic vtlR mutant cells
GEO Series GSE69564. Brucella abortus. 6 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.