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23 results for “Brugia malayi”
Fig. 3 in The Wolbachia endosymbiont of Brugia malayi has an active phosphoglycerate mutase: a candidate target for anti-filarial therapies
Fig. 3 Activity of recombinant wBm–iPGM. Conversion of 3-PG to 2-PG by MBP–wBm–iPGM (filled circle) is measured indirectly by a decrease in NADH concentration, determined spectrophotometrically at 340 nm. Consumption of NADH is directly proportional to PGM activity. A baseline control lacking wBm–iPGM (open circle) is shown
Fig. 1 in The Wolbachia endosymbiont of Brugia malayi has an active phosphoglycerate mutase: a candidate target for anti-filarial therapies
Fig. 1 Alignment of the deduced amino acid sequences of various iPGM enzymes. The sequence of iPGM from the Wolbachia endosymbiont of Brugia malayi (wBm; GenBank accession no. AAW70991) is aligned with the extensively studied and structurally characterized iPGM from Bacillus stearothermophilus (Bs; GenBank accession no. Q9X519; Jedrzejas et al. 2000a,b) and the characterized iPGM from Brugia malayi (Bm; GenBank accession no. AAQ97626; Zhang et al. 2004; Raverdy et al. 2007). Residues that are identical in at least two of the three sequences are shaded in black, while conserved amino acid changes are grey. The catalytic serine (@) and 13 other residues (*) involved in catalysis (Jedrzejas 2000) are conserved in all three enzymes. Alignment generated with ClustalW and displayed with BOXSHADE (www.ch.embnet.org/software/ BOX_form.html)
Fig. 2 in The Wolbachia endosymbiont of Brugia malayi has an active phosphoglycerate mutase: a candidate target for anti-filarial therapies
Fig. 2 Purification of MBP–wBm–iPGM expressed intracellularly in the yeast K. lactis. Fractions from the purification were analyzed by SDS-PAGE and the gel stained with Coomassie Blue. Lane 1 Protein Ladder (New England Biolabs), lane 2 K. lactis lysate, lane 3 supernatant of K. lactis lysate, lane 4 pellet of K. lactis lysate, lane 5 flow-through from amylose column, lane 6 column wash, lanes 7, 8, and 9, elution fractions. The arrowhead indicates the protein band corresponding to recombinant MBP–wBm–iPGM
Data from: Positive allosteric modulation of emodepside sensitive <em>Brugia malayi</em> SLO-1F and <em>Onchocerca volvulus</em> SLO-1A potassium channels by GoSlo-SR-5-69
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Data from: Diethylcarbamazine elicits calcium signals in HEK293 cells by activation of heterologously expressed <em>Brugia malayi</em> TRP-2b channels
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Single-cell RNA-seq datasets derived from human parasitic nematode Brugia malayi microfilariae
<p>Single-cell RNA-seq data of the parasitic nematode <em>Brugia malayi</em> in the microfilariae development stage. Data includes untreated cellular transcriptional states and the transcriptional response to ivermectin (1 µM). </p> <p>The unfiltered gene expression matrix is provided as both a Seurat and AnnData object. Filtered datasets are provided as .csv files for direct import into R. </p>
The effect of in vitro cultivation on the transcriptome of adult Brugia malayi
GEO Series GSE72592. Brugia malayi. 24 samples. Type: Expression profiling by high throughput sequencing.
Brugia malayi mature vs immature microfilariae
GEO Series GSE14940. Brugia malayi. 4 samples. Type: Expression profiling by array.
Deciphering the loss of fertility in ivermectin-treated Brugia malayi females in vitro: a transcriptomic approach [Study II]
GEO Series GSE75340. Brugia malayi. 20 samples. Type: Expression profiling by high throughput sequencing.
The effect on anthelmintic drugs on Brugia malayi gene expression in vivo
GEO Series GSE99334. Brugia malayi. 68 samples. Type: Expression profiling by high throughput sequencing.
Deciphering the loss of fertility in ivermectin-treated Brugia malayi females in vitro: a transcriptomic approach [Study I]
GEO Series GSE75339. Brugia malayi. 14 samples. Type: Expression profiling by high throughput sequencing.
Effect of Doxycycline on Wolbachia and Brugia malayi adult female worms in vivo
GEO Series GSE34976. Brugia malayi; Onchocerca volvulus; Wolbachia endosymbiont strain TRS of Brugia malayi; Wuchereria bancrofti. 8 samples. Type: Expression profiling by array.
Brugia malayi filarial helminth-derived extracellular vesicles suppress antigen presenting cell functions and antigen-specific CD4+ T cell responses
GEO Series GSE263690. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Profiling of gender-regulated gene transcripts in the filarial nematode Brugia malayi by oligonucleotide array analysis
GEO Series GSE2038. Brugia malayi. 8 samples. Type: Expression profiling by array.
Induction of TRAIL and TNF-alpha-dependent Apoptosis in Human mDCs by Microfilariae of Brugia Malayi
GEO Series GSE12787. Homo sapiens. 2 samples. Type: Expression profiling by array.
Deciphering the loss of fertility in ivermectin-treated Brugia malayi females in vitro: a transcriptomic approach
GEO Series GSE75341. Brugia malayi. 34 samples. Type: Expression profiling by high throughput sequencing.
Microarray analysis of Brugia malayi microfilariae-derived extracellular vesicles (Evs) and supernatants
GEO Series GSE157226. Brugia malayi; synthetic construct. 9 samples. Type: Non-coding RNA profiling by array.
Profiling of gender based transcripts of Brugia malayi
GEO Series GSE12944. Brugia malayi. 3 samples. Type: Expression profiling by array.
Identification of cross-species microRNA-based Communication in Brugia malayi with its endosymbiont Wolbachia
GEO Series GSE143730. Brugia malayi; Wolbachia endosymbiont of Brugia malayi. 21 samples. Type: Non-coding RNA profiling by high throughput sequencing.
mRNA Sequencing of human monocyte cell lines exposed to Brugia malayi filarial helminth-derived extracellular vesicles.
GEO Series GSE263693. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.