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181 results for “CHO”
Raw data to accompany the manuscript 'Data for Engineering Lipid Metabolism of Chinese Hamster Ovary (CHO) Cells for Enhanced Recombinant Protein Production' published in the Journal Data in Brief
<p>This repository consists of the raw western blot, microscopy and mass spectrometry data to accompany the manuscript 'Data for Engineering Lipid Metabolism of Chinese Hamster Ovary (CHO) Cells for Enhanced Recombinant Protein Production' published in the Journal Data in Brief and associated with the article '<a href="https://www.ncbi.nlm.nih.gov/pubmed/31805379">Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production</a>' published in the journal Metabolic Engineering (see DOI: 10.1016/j.ymben.2019.11.007). </p> <p>The western blot raw file is associated with Figure 1a and 1b of the Data in Brief manuscript.</p> <p>The confocal microscopy raw image files (x3) are associated with Figure 1c of the Data in Brief manuscript.</p> <p>The mass spectrometry files are the raw data that refers to the samples presented in Figure 5 of the Data in Brief manuscript. Files are labelled as in the Data in Brief and Metabolic Engineering manuscripts. The file name structures is as follows;</p> <p>CHO-Controlpoolai</p> <p>Where 'a' represents replicate 'a' of three biological replicates and 'i' refers to mass spectrometry technical analysis 1 of 3 technical analyses of each replicate (thus for each cell pool or line there are three biological replicates that are each analysed in triplicate such that there are 9 raw mass spectrometry files for each cell pool or line).</p> <p>All the mass spectrometry files are found in the compressed (zip) file named mass_spectrometry_raw_files_archive.zip</p>
FAIR-CHO Citation Model Zotero Group Library Bibliography. Supplementary material
<p>This is a selected bibliography created during the project <em>A FAIR-enabling citation model for Cultural Heritage Objects</em>.</p> <p>This bibliography has been set up via a Zotero Library Group, by organizing it into subject folders representative of the project content. An initial list of descriptors was also defined to 'semantically' label the bibliographic references as they were collected.</p> <p>The dataset represents the Zotero Library on 1st August 2023.</p> <p>The dataset is published in .csv and .ris formats.</p> <p>See also on Zotero Groups: <a href="https://www.zotero.org/groups/4883319/cho_citation_model/library">https://www.zotero.org/groups/4883319/cho_citation_model/library</a>.</p>
Predictive nano-QSAR modeling of the cytotoxicity using epithelial cells obtained from Chinese hamster ovary (CHO-K1 cell line) for hybrid TiO2-based nanomaterials
<p>Results obtained from developed model indicated that the cytotoxicity of hybrid TiO2-based nanomaterials is related to additive electronegativity (χmix) of studied nanomaterials that are indirectly related to the electron generation and ROS formation. ROS production is the most common toxicity cause as discussed in the literature in the case of nanoparticles. The high efficiency of surface modified TiO2-based semiconductors can be attributed to the involvement of TiO2 band gap (Eg) excitation and absence of noble metals at the TiO2 surface. It can be expected that noble metals (i.e. Pd/Pt) may trap holes (h+), at the same time photo-generated electrons can be then transferred from the valence band to the conduction band of TiO2 and to its surface where redox processes were initiated. Thus, observed reduction of the electron–hole pair recombination influences the reactive oxygen species (ROS) formation and the photocatalytic redox process initiation.</p> <p>Since the electronegativity was positively correlated with the cytotoxicity it can be expected that some ions are released from the TiO2 surface easier than others.</p>
In-house CHO HCP Platform: a promising approach for HCP ELISA monitoring
Open the record for dataset details and reuse information.
Annotation of the non-canonical translatome reveals that CHO cell microproteins are a new class of therapeutic antibody drug product impurity
<p>3,681 novel Chinese hamster proteoforms (derived from uORFs, ouORFs and ORFs encoded on NCBI annotated non-coding RNAs).</p>
Discrete Feature Representations of CHO Reaction Mechanisms as Quasireaction Subgraphs
<p>This data set contains 194778 quasireaction subgraphs extracted from CHO transition networks with 2-6 non-hydrogen atoms (CxHyOz, 2 <= x + z <= 6).</p> <p>The complete table of subgraphs (including file locations) is in CHO-6-atoms-subgraphs.csv file. The subgraphs are in GraphML format (http://graphml.graphdrawing.org) and are compressed using bzip2. All subgraphs are undirected and unweighted. The reactant and product nodes (initial and final) are labeled in the "type" node attribute. The nodes are represented as multi-molecule SMILES strings. The edges are labeled by the reaction rules in SMARTS representation. The forward and backward reading of the SMARTS string should be considered equivalent.</p> <p>The generation and analysis of this data set is described in<br> D. Rappoport, Statistics and Bias-Free Sampling of Reaction Mechanisms from Reaction Network Models, 2023, submitted. Preprint at ChemrXiv, DOI: 10.26434/chemrxiv-2023-wltcr</p> <p>Simulation parameters<br> - CHO networks constructed using polar bond break/bond formation rule set for CHO.<br> - High-energy nodes were excluded using the following rules:<br> (i) more than 3 rings, (ii) triple and allene bonds in rings, (iii) double bonds at<br> bridge atoms,(iv) double bonds in fused 3-membered rings.<br> - Neutral nodes were defined as containing only neutral molecules.<br> - Shortest path lengths were determined for all pairs of neutral nodes.<br> - Pairs of neutral nodes with shortest-path length > 8 were excluded.<br> - Additionally, pairs of neutral nodes connected only by shortest paths passing through<br> additional neutral nodes (reducible paths) were excluded.</p> <p>For background and additional details, see paper above.</p>
Raw data and analysis results in paper by Cho and Iwata published in JGR
<p>Thirty-two microtremor arrays were analyzed in Cho and Iwata (2021) (Cho, I., & Iwata, T., 2021, Limits and benefits of the spatial autocorrelation microtremor array method due to the incoherent noise, with special reference to the analysis of long wavelength ranges. Journal of Geophysical Research: Solid Earth, 126, e2020JB019850. https://doi.org/10.1029/2020JB019850). This archive includes the raw digital data of microtremors and analysis results, plots of the processing results of individual arrays, and script files to plot some graphs.</p> <p> </p>
Archive of the microtremor data used in Cho and Nakazawa 2024
<p>This archive includes microtremor data and the analysis results used in "Shallow microtremor survey using miniature and small arrays: Strategy for efficient and feasible dense survey" by Ikuo Cho and Tsutomu Nakazawa (2024, Earth and Space Science). </p>
FIGURE 2 in Lindavia biswashanti, a new diatom species (Bacillariophyta) from Gokyo Cho, Himalayan Range, Nepal
FIGURE 2: Size diminution series of Lindavia biswashanti. Light microscope images captured under a Leica DM2500. The holotype specimen is image C. Scale bars are all 10 μm. The central fultoportula is readily visible in larger specimens (A–F) and slightly offset from the center of the valve. Rimoportulae are indistinct in light microscope. The distinguishing features are the three triangular-shaped raised areas juxtaposed with three lowered areas to make six sectors in a superficial likeness of the nuclear fallout-shelter symbol.
FIGURE 3 in Lindavia biswashanti, a new diatom species (Bacillariophyta) from Gokyo Cho, Himalayan Range, Nepal
FIGURE 3: Scanning electron micrographs of Lindavia biswashanti. Image A exhibits the external view with central fultoportula (cfp), rimoportula (rp), and marginal fultoportulae of which one is arrowed (mfp). Image B is a small specimen that exhibits granules around the margin. Interior expressions of the central fultoportula, rimoportula, and marginal fultoportula are shown in images D & E. Image F is a close up of the rimoportula and marginal fultoportula shown in image D.
FIGURE 1 in Lindavia biswashanti, a new diatom species (Bacillariophyta) from Gokyo Cho, Himalayan Range, Nepal
FIGURE 1: Map of the Sagarmatha National Park region, Province No. 1, Solukhumbu District, Nepal. The region is dominated by some of the tallest peaks in the world. Mount Everest (8,848 m) and Cho Oyu (8,188 m) are shown. The lakes from which samples were collected comprise some of the highest elevation lakes in the world. Gokyo Cho is the locality from which the holotype material is collected. Location of the region in the Himalayas (inset).
Supplementary material 1 from: Lee W, Kim JS, Seo CW, Lee JW, Kim SH, Cho Y, Lim YW (2023) Diversity of Cladosporium (Cladosporiales, Cladosporiaceae) species in marine environments and report on five new species. MycoKeys 98: 87-111. https://doi.org/10.3897/mycokeys.98.101918
Strains of Cladosporium isolated in this study with detailed information on habitats and regions and GenBank accession numbers
Safety, and Immunogenicity Study of the Recombinant Two-component COVID-19 Vaccine (CHO Cell)
ClinicalTrials.gov study NCT05084989. IPD Sharing: NO. Countries: 1. Publications: 2.
To Evaluate the Immunogenicity and Safety of Sequential Booster Immunization of Recombinant Novel Coronavirus Vaccine (CHO Cells) for SARS-CoV-2
ClinicalTrials.gov study NCT05895110. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Trial Evaluate the Immunogenicity and Safety of Recombinant COVID-19 Omicron-Delta Variant Vaccine (CHO Cell)
ClinicalTrials.gov study NCT05616754. IPD Sharing: NO. Countries: 1. Publications: 1.
A Phase II Clinical Trial to Evaluate the Immunogenicity and Reactogenicity of the Recombinant HIV-1 Envelope Vaccines SF-2 rgp120 (CHO) [Chiron Vaccines] in MF59 Adjuvant and MN rgp120/HIV-1 [VaxGen]
ClinicalTrials.gov study NCT00001031. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cells,NVSI-06-08) and Inactivated COVID-19 Vaccine (Vero Cells) in Population Aged 18 Years and Above
ClinicalTrials.gov study NCT05069129. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Phase II Clinical Trial of Recombinant SARS-CoV-2 Spike Protein Vaccine (CHO Cell) for the Prevention of COVID-19
ClinicalTrials.gov study NCT04990544. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Immunogenicity and Safety of Recombinant COVID-19 Vaccine (CHO Cells)
ClinicalTrials.gov study NCT04813562. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Omicron BA.4/5-Delta Strain Recombinant Novel Coronavirus Protein Vaccine (CHO Cells)
ClinicalTrials.gov study NCT05850507. IPD Sharing: Not stated. Countries: 1. Publications: 2.
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.