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ShareScore release 0.9.0
Dataset results
25 results for “CRISPR interference”
Tuning apicobasal polarity and junctional recycling in the hemogenic endothelium orchestrates the morphodynamic complexity of emerging pre-hematopoietic stem cells —Source data 4 relative to Figure 7 – ArhGEF11 CRISPR interference
<p><span>Raw image files (TIFF format), corresponding 2D-cartographies (_2Dmap.tiff files) and metadata files for 2D-cartographies (.xml files, readable with the opensource software Icy), relative to <strong>Figure 7B </strong>and<strong> Figure 7 - Figure Supplement 6</strong> (see <strong>Materials and Methods — Morphological and morphometric analysis of aortic and hemogenic cells</strong>).</span></p> <p><span>The source data comprises for each 48 - 55 hpf <em>Tg(kdrl:eGFP-JAM3b; kdrl:nls-mKate2)</em> zebrafish embryo 3 z-stack and 2D cartographies (segments 1 to 3) encompassing the whole length of the aorta, for control condition (n = 2 individuals) and morpholino splicing interference condition (n = 2 individuals). For z-stacks of both control and morphant conditions, two fluorescence channels were acquired, corresponding to the nuclear mKate2 expressed in endothelial cells and the eGFP-JAMs signal localized at the intercellular junctions of endothelial cells. Z-stack were acquired using a confocal spinning disk microscope. Voxel size: x: 0.1635, y: 0.1635, z:0.3 µm. 2D-cartographies were obtained using the Icy plugin “TubeSkinner”, and the semi-manual segmentation of all aortic cells can be uploaded from the corresponding metadata file on the 2D-cartographies using the load ROI function of Icy.</span></p>
Data: Linking CRISPR-Cas9 interference in cassava to the evolution of editing-resistant geminiviruses
<p>Dataset of raw SMRT sequence data and processed data including alignments of virus sequences edited using CRISPR-Cas9 technology in cassava plants.</p> <p> </p>
CRISPR activation and interference screens decode stimulation responses in primary human T cells [Bulk RNA-seq]
GEO Series GSE174284. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
MNK3 cells with CRISPR interference or activation at the CLN3 gene
GEO Series GSE313942. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Integrating CRISPR knockout, interference, and activation to dissect the functional role and underlying signaling of microRNA-23a-27a-24-2 cluster in hepatocellular carcinoma
GEO Series GSE199332. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeted CRISPR interference and activation of microRNA-3662-HBP1 axis controls tumor progression of triple-negative breast cancer
GEO Series GSE169128. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
CRISPR activation and interference screens decode stimulation responses in primary human T cells [CRISPRa Perturb-seq]
GEO Series GSE190604. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing; Other.
Systematic mapping of functional enhancer-promoter connections with CRISPR interference
GEO Series GSE87257. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
CRISPR activation and interference screens decode stimulation responses in primary human T cells [Supplemental CRISPR]
GEO Series GSE190846. Homo sapiens. 16 samples. Type: Other.
U937 cells with CRISPR interference at regulatory genetic variants [ATAC-seq]
GEO Series GSE281908. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide CRISPR interference screen identifies long non-coding RNA DARS1-AS1 as a novel regulator of glioblastoma tumorigenesis.
GEO Series GSE213046. Homo sapiens. 28 samples. Type: Other.
A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling
GEO Series GSE140745. Homo sapiens. 21 samples. Type: Other.
An inducible CRISPR-interference library for genetic interrogation of Saccharomyces cerevisiae biology
GEO Series GSE159409. Saccharomyces cerevisiae; Escherichia coli. 20 samples. Type: Other.
Parallel quantitative CRISPR interference in yeast identifies chemical-genetic interactions and new rules for guide RNA design
GEO Series GSE71490. Saccharomyces cerevisiae. 84 samples. Type: Other.
U937 cells with CRISPR interference at regulatory genetic variants [4C-seq]
GEO Series GSE281909. Homo sapiens. 6 samples. Type: Other.
Identification of the alternative sigma factor regulons of Chlamydia trachomatis using multiplexed CRISPR interference
GEO Series GSE230645. Chlamydia trachomatis L2/434/Bu. 48 samples. Type: Expression profiling by high throughput sequencing.
CRISPR interference reveals that all-trans-retinoic acid promotes macrophage control of Mycobacterium tuberculosis by limiting bacterial access to cholesterol and propionyl-CoA
GEO Series GSE183912. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
CRISPR activation and interference screens decode stimulation responses in primary human T cells [CRISPR]
GEO Series GSE174255. Homo sapiens; unidentified plasmid. 52 samples. Type: Other.
CRISPR activation and interference screens decode stimulation responses in primary human T cells
GEO Series GSE174292. Homo sapiens; unidentified plasmid. 68 samples. Type: Expression profiling by high throughput sequencing; Other.
Pervasive off-target activity in CRISPR-interference (CRISPRi) system [RNA-seq]
GEO Series GSE252977. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.