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10 results for “Caffeine citrate”
Caffeine citrate status, availability and practice across Nigeria, Ethiopia, Kenya, South Africa and five States in India
<p>Apnea of prematurity (AOP) is a common complication among preterm infants (<37 weeks gestation), globally. However, access to caffeine citrate (CC) that is a proven safe and effective treatment in high income countries is largely unavailable in low-and-middle income countries, where most preterm infants are born. Therefore, the overall aim of this study was to describe the demand, policies, and supply factors affecting the availability and clinical use of CC in LMICs.</p> <p>A mixed methods approach was used to collect data from diverse settings in LMICs including Ethiopia, Kenya, Nigeria, South Africa, and India. Qualitative semi-structured interviews and focus group discussions were conducted with different health care providers, policymakers, and stakeholders from industry. Additional data was collected using standard questionnaires. A thematic framework approach was used to analyze the qualitative data and descriptive statistics were used to summarize the quantitative data. The findings indicate that there is variation in in-country policies on the use of CC in the prevention and treatment of AOP and its availability across the LMICs. As a result, the knowledge and experience of using CC also varied with clinicians on Ethiopia having no experience of using it while those in India have greater knowledge and experience of using it. The in turn influenced the demand and our findings show that only 29% of eligible preterm infants are receiving CC in these countries.</p> <p>There is an urgent need to address the multilevel barriers to accessing CC for management of AOP in Africa. These include cost, lack of national policies and therefore lack of demand stemming from its clinical equivalency with aminophylline. Practical ways to reduce the cost of CC in LMICs could potentially increase its availability and use.</p>
Caffeine citrate status, availability and practice across Nigeria, Ethiopia, Kenya, South Africa and five States in India
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Effect of Early Use of Caffeine Citrate in Preterm Neonates
ClinicalTrials.gov study NCT04001712. IPD Sharing: Not stated. Countries: 1. Publications: 3.
The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate
ClinicalTrials.gov study NCT06401083. IPD Sharing: UNDECIDED. Countries: 1. Publications: 13.
Caffeine Citrate for the Treatment of Apnea Associated With Bronchiolitis in Young Infants
ClinicalTrials.gov study NCT01435486. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Apnea of Prematurity Results in Respiratory Distress and Cyanosis. Caffeine Citrate Can Treat It.
ClinicalTrials.gov study NCT06905496. IPD Sharing: NO. Countries: 1. Publications: 0.
Caffeine Citrate Use and Electronic Activity of the Diaphragm (EDI) Changes
ClinicalTrials.gov study NCT05393817. IPD Sharing: NO. Countries: 1. Publications: 0.
Caffeine and Sodium Citrate Ingestion
ClinicalTrials.gov study NCT01591226. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Caffeine Citrate in Preterm Infants at Risk of Apnea in Zambia
ClinicalTrials.gov study NCT06518603. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Caffeine Citrate to Improve Neonatal Outcomes.
ClinicalTrials.gov study NCT06972849. IPD Sharing: YES. Countries: 0. Publications: 0.
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