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72
datasets available to search
ShareScore release 0.9.0
Dataset results
72 results for “Cancer Prevention and Treatment”
Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions
ClinicalTrials.gov study NCT02135419. IPD Sharing: YES. Countries: 2. Publications: 4.
Exploratory Study of ART-123 for the Prevention of Cancer Treatment Related Symptoms in Patients With Postoperative Stage II / III Colon Cancer
ClinicalTrials.gov study NCT02792842. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Preventive Treatment of Oxaliplatin Induced Peripheral Neuropathy in Metastatic Colorectal Cancer (POLAR-M)
ClinicalTrials.gov study NCT03654729. IPD Sharing: NO. Countries: 13. Publications: 1.
Evaluating the Effectiveness of Escitalopram to Prevent Depression in Head and Neck Cancer Patients Receiving Treatment
ClinicalTrials.gov study NCT00536172. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Magnesium Treatment on Vitamin D Metabolism in Participants Completed Personalized Prevention of Colorectal Cancer Trial
ClinicalTrials.gov study NCT03265483. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Preventive Treatment of OxaLiplatin Induced peripherAl neuRopathy in Adjuvant Colorectal Cancer
ClinicalTrials.gov study NCT04034355. IPD Sharing: NO. Countries: 10. Publications: 1.
Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women Receiving Letrozole for Breast Cancer.
ClinicalTrials.gov study NCT00171340. IPD Sharing: Not stated. Countries: 28. Publications: 2.
Data from: A clinical decision support system learned from data to personalize treatment recommendations towards preventing breast cancer metastasis
Objective: A Clinical Decision Support System (CDSS) that can amass Electronic Health Record (EHR) and other patient data holds promise to provide accurate classification and guide treatment choices. Our objective is to develop the Decision Support System for Making Personalized Assessments and Recommendations Concerning Breast Cancer Patients (DPAC), which is a CDSS learned from data that recommends the optimal treatment decisions based on a patient's features. Method: We developed a Bayesian network architecture called Causal Modeling with Internal Layers (CAMIL), and an algorithm called Treatment Feature Interactions (TFI), which learns from data the interactions needed in a CAMIL model. Using the TFI algorithm, we learned interactions for six treatments from the Lynn Sage Data Set (LSDS). We created a CAMIL model using these interactions, resulting in a DPAC which recommends treatments towards preventing 5-year breast cancer metastasis. Results: In a 5-fold cross-validation analysis, we compared the probability of being metastasis free in 5 years for patients who made decisions recommended by DPAC to those who did not. These probabilities are (the probability for those making the decisions appears first): chemotherapy (.938, .872); breast/chest wall radiation (.939, .902); nodal field radiation (.940, .784); antihormone (.941, .906); HER2 inhibitors (.934, .880); neadjuvant therapy (.931, .837). In an application of DPAC to the independent METABRIC dataset, the probabilities for chemotherapy were (.845, .788). Discussion: Patients who took the advice of DPAC had, as a group, notably better outcomes than those who did not. We conclude that DPAC is effective at amassing and analyzing data towards treatment recommendations. Some of the findings in DPAC are controversial. For example, DPAC says that chemotherapy increases the chances of metastasis for many node negative patients. This controversy shows the importance of developing a conclusive version of DPAC to ensure we provide patients with the best patient-specific treatment recommendations.
A Non-interventional Study on Xarelto for Treatment of Venous Thromboembolism (VTE) and Prevention of Recurrent VTE in Patients With Active Cancer
ClinicalTrials.gov study NCT02742623. IPD Sharing: Not stated. Countries: 10. Publications: 2.
Selective Axillary Lymph Node Dissection Vs Complete Axillary Dissection: A Randomised Clinical Trial to Assess the Prevention of Lymphedema in Breast Cancer Treatment
ClinicalTrials.gov study NCT03083314. IPD Sharing: NO. Countries: 1. Publications: 7.
Xian-Lian-Jie-Du Optimization Decoction As an Adjuvant Treatment for Prevention of Recurrence of Colon Cancer
ClinicalTrials.gov study NCT05709249. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Edible Plant Exosome Ability to Prevent Oral Mucositis Associated With Chemoradiation Treatment of Head and Neck Cancer
ClinicalTrials.gov study NCT01668849. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Caelyx in Ovarian Cancer: Prevention and Treatment of Infusion Reactions and Palmar-plantar Erythrodysesthesia (Study P04085)(COMPLETED)
ClinicalTrials.gov study NCT00743431. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment
ClinicalTrials.gov study NCT00066248. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Clinical Trial of Qizhu Yuling Prescription in the Prevention and Treatment of Esophagus Cancer
ClinicalTrials.gov study NCT05626309. IPD Sharing: YES. Countries: 1. Publications: 1.
Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment
ClinicalTrials.gov study NCT02253251. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Donepezil and Vitamin E to Prevent Side Effects Caused By Radiation Therapy to the Head in Patients Receiving Treatment for Small Cell Lung Cancer
ClinicalTrials.gov study NCT00006349. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Prevent Rash in People Starting Alpelisib for the Treatment of Breast Cancer
ClinicalTrials.gov study NCT05966584. IPD Sharing: YES. Countries: 1. Publications: 0.
COVID-19 Prevention and Treatment in Cancer; a Sequential Multiple Assignment Randomised Trial;
ClinicalTrials.gov study NCT04534725. IPD Sharing: NO. Countries: 1. Publications: 2.
Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)
ClinicalTrials.gov study NCT05465031. IPD Sharing: NO. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.