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9 results for “Candida tropicalis”
Evaluación de la Producción de Xilitol mediante Modelos Genómicos en Candida tropicalis
<p>La reducción biotecnológica de xilosa a xilitol utilizando levaduras del género Candida sp., apoyada por técnicas de ingeniería metabólica y modelos metabólicos a escala genómica, mejora la producción de xilitol, ofreciendo un proceso más eficiente, rentable y beneficioso para el medio ambiente en las industrias alimentaria y sanitaria.</p>
Data from: Multilocus microsatellite markers for molecular typing of Candida tropicalis isolates
Background: Candida tropicalis is considered to be the leading pathogen causing nosocomial fungemia and hepatosplenic fungal infections in patients with cancer, particularly those with leukemia. Microsatellite-based typing methods using sets of genetic markers have been developed and reported for population structure analysis of C. albicans, C. glabrata, and C. parapsilosis, but no studies have been published for genetic analysis of C. tropicalis. The objective of this study was to develop new microsatellite loci that have the ability to distinguish among C. tropicalis isolates. Results: DNA sequences containing over 10 bi- or tri-nucleotide repeats were selected from the C. tropicalis genome database. Thirty PCR primers sets specific for the microsatellite loci were designed and tested using eight clinically independent isolates. According to the amplification efficiency, specificity, and observed polymorphisms, eight markers were selected for further population structure analysis and molecular typing. Sixty-five independent C. tropicalis isolates were genotyped using these 8 markers. Based on these analyses, six microsatellite loci were confirmed, although two loci were found to be with unstable flanking areas. The six polymorphic loci displayed 4–22 alleles and 7–27 genotypes. The discriminatory power of the six loci ranged from 0.70 to 0.95. Genotyping results obtained by microsatellite analysis were compared to PCR-fingerprinting and multi-locus sequence typing (MLST). The comparisons showed that microsatellite analysis and MLST had the similar discriminatory power for C. tropicalis, which were more powerful than PCR-fingerprinting. Conclusions: This is the first attempt to develop new microsatellite loci for C. tropicalis. These newly developed markers will be a valuable resource for the differentiation of C. tropicalis isolates. More C. tropicalis isolates will need to be sequenced and analyzed in order to fully show the potential of these newly developed microsatellite markers.
Data from: Multilocus microsatellite markers for molecular typing of Candida tropicalis isolates
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Homo sapiens whole blood infected with Candida spp. (here: Candida tropicalis)
GEO Series GSE114178. Candida tropicalis; Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
The gray phenotype in the human fungal pathogen Candida tropicalis
GEO Series GSE81514. Candida tropicalis. 3 samples. Type: Expression profiling by high throughput sequencing.
Regulation of filamentation in the human fungal pathogen Candida tropicalis
GEO Series GSE73340. Candida tropicalis MYA-3404. 2 samples. Type: Expression profiling by high throughput sequencing.
Discovery of a phenotypic switch regulating sexual mating in the opportunistic fungal pathogen Candida tropicalis
GEO Series GSE40179. Candida tropicalis. 8 samples. Type: Expression profiling by array.
Candida tropicalis biofilm formation under secondary bile salt sodium deoxycholate
GEO Series GSE315217. Candida tropicalis; Candida albicans. 12 samples. Type: Expression profiling by high throughput sequencing.
Environmental and genetic regulation of white-opaque switching in Candida tropicalis
GEO Series GSE101999. Candida tropicalis. 6 samples. Type: Expression profiling by high throughput sequencing.
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