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4 results for “CanineHD BeadChip”
CanineHD 230 K BeadChip data from Pembroke Welsh corgi
<p><span>Several hundred disease-causing mutations are currently known in domestic dogs. Breeding management is therefore required to minimize their spread. Recently, genetic methods such as direct-to-consumer testing have gained popularity; however, their effects on dog populations are unclear. </span></p> <p><span>Here, we aimed to evaluate the influence of genetic testing on the frequency of mutations responsible for canine degenerative myelopathy (DM) and assess the changes in the genetic structure of a Pembroke Welsh corgi population from Japan. </span></p> <p><span>To evaluate the influence of genetic testing on the frequency of mutations causing canine degenerative myelopathy and changes to genetic structure in the Pembroke Welsh corgi population from Japan, 117 dogs were genotyped.</span></p> <p><span>Weir and Cockerham population differentiation (FST) based on genome-wide single-nucleotide polymorphism (SNP) detected the SNP with the highest FST located in the intron of SOD1 adjacent to the c.118G>A mutation, supporting a selection signature on SOD1. Further genome-wide SNP analyses revealed no obvious changes in inbreeding levels between the 2019 and 2022 populations. </span></p> <p><span>Our study highlights that genetic testing can help inform improved mating choices in breeding programs to reduce the frequency of risk variants and avoid inbreeding.</span></p>
CanineHD 230 K BeadChip data from Pembroke Welsh corgi
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CanineHD 230 K BeadChip data from Miniature Dachshunds
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Comparison of variant calling pipelines using Illumina CanineHD BeadChip array as the truth dataset
GEO Series GSE117010. Canis lupus familiaris. 7 samples. Type: Genome variation profiling by SNP array; SNP genotyping by SNP array.
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International Brain Laboratory public data
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OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.