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26
datasets available to search
ShareScore release 0.9.0
Dataset results
26 results for “Cas12a”
Supplemental files to: Probe-based quantitative PCR and RPA-Cas12a molecular diagnostics for detection of the tomato pest Phthorimaea absoluta (Lepidoptera: Gelechiidae)
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Electrochemical Biosensing of Tuberculosis using CRISPR-Cas12a and redox-probe modified oligonucleotide
<p>We have submitted the manuscript in HELIYON </p> <p><span>Manuscript. Number: HELIYON-D-24-20798R3 </span></p> <p>Title: An electrochemical biosensor for the detection of tuberculosis specific DNA with CRISPR-Cas12a and redox-probe modified oligonucleotide. </p> <p>The dataset used in that study is available here. </p>
CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells
<p>We identified and characterized potential integration safe harbor sites (SHS) in human cells. Using the CRISPR-MAD7 system, we integrated transgenes at these genomic sites in iPSC, primary T and NK cells, and Jurkat cell line, and demonstrated efficient and stable expression at these loci. Subsequently, we validated the differentiation capabilities of engineered iPSC towards CD34+ hematopoietic stem and progenitor cells (HSPC), lymphoid progenitors (LPC), and natural killer (NK) cells, and showed that transgene expression was retained in these lineages. </p>
Live cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a
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Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9-Cas12a platform
GEO Series GSE144281. Homo sapiens; Mus musculus. 14 samples. Type: Other.
Optimized CRISPR-Cas12a platform for combinatorial drop-out genetic screening (RNA-seq)
GEO Series GSE141130. Mus musculus. 29 samples. Type: Expression profiling by high throughput sequencing.
Cas12a base editors induce efficient and specific editing with low DNA damage response
GEO Series GSE145552. Mus musculus; Homo sapiens. 265 samples. Type: Expression profiling by high throughput sequencing; Other.
Systematic optimization of Cas12a base editors in wheat and maize using the ITER platform
GEO Series GSE200450. Triticum aestivum; Zea mays. 29 samples. Type: Other.
A Cas12a ortholog with stringent PAM recognition followed by low off-target editing rates for genome editing
GEO Series GSE146420. Homo sapiens; synthetic construct. 195 samples. Type: Other.
Engineered CRISPR-Cas12a for higher-order combinatorial chromatin perturbations (Nanopore)
GEO Series GSE260827. Homo sapiens. 4 samples. Type: Other.
Dual nuclease single-cell lineage tracing by Cas9 and Cas12a
GEO Series GSE261211. Mus musculus; Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing; Other.
High targeted integration frequency in human pluripotent stem cells with the CRISPR-Cas12a Ultra system
GEO Series GSE249731. Homo sapiens. 6 samples. Type: Other.
Optimization of Cas12a for multiplexed genome- scale transcriptional activation
GEO Series GSE231789. Homo sapiens. 10 samples. Type: Other.
Randomized PAM depletion of phylogenetically-diverse Cas12a nucleases
GEO Series GSE130377. synthetic construct. 12 samples. Type: Other.
Engineered CRISPR-Cas12a for higher-order combinatorial chromatin perturbations (RNA-Seq)
GEO Series GSE260828. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
Engineered CRISPR-Cas12a for higher-order combinatorial chromatin perturbations (CRISPR screen)
GEO Series GSE260829. synthetic construct; Homo sapiens. 12 samples. Type: Other.
Engineered CRISPR-Cas12a for higher-order combinatorial chromatin perturbations
GEO Series GSE260832. Homo sapiens; synthetic construct. 42 samples. Type: Expression profiling by high throughput sequencing; Other.
Cas12a base editors induce efficient and specific editing with low DNA damage response (DNA targeted sequencing)
GEO Series GSE145550. Homo sapiens; Mus musculus. 248 samples. Type: Other.
Cas12a base editors induce efficient and specific editing with low DNA damage response (RNA sequencing)
GEO Series GSE144278. Homo sapiens. 17 samples. Type: Other.
Engineered CRISPR-Cas12a for higher-order combinatorial chromatin perturbations (amplicon)
GEO Series GSE260830. Homo sapiens. 19 samples. Type: Other.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.