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Dataset results
44 results for “Cell Spreading”
The spreading of magnetic reconnection X-line in particle-in-cell simulations– mechanism and the effect of drift-kink instability
<p>This dataset contains data and Python scripts in "The spreading of magnetic reconnection X-line in particle-in-cell simulations– mechanism and the effect of drift-kink instability" prepared to submit to the Journal of Geophysical Research. </p>
A multiscale theory for spreading and migration of adhesion-reinforced mesenchymal cells
<p>We present a chemomechanical whole-cell theory for the spreading and migration dynamics of mesenchymal cells that can actively reinforce their adhesion to an underlying viscoelastic substrate as a function of its stiffness. Our multiscale model couples the adhesion reinforcement effect at the subcellular scale with the nonlinear mechanics of the nucleus-cytoskeletal network complex at the cellular scale to explain the concurrent monotonic area-stiffness and non-monotonic speed-stiffness relationships observed in experiments: We consider that large cell spreading on stiff substrates flattens the nucleus, increasing the viscous drag force on it. The resulting force balance dictates a reduction in the migration speed on stiff substrates. We also reproduce the experimental influence of the substrate viscosity on the cell spreading area and migration speed by elucidating how the viscosity may either maintain adhesion reinforcement or prevent it depending on the substrate stiffness. Additionally, our model captures the experimental directed migration behavior of the adhesion-reinforced cells along a stiffness gradient, known as durotaxis, as well as up or down a viscosity gradient (viscotaxis or anti-viscotaxis), the cell moving towards an optimal viscosity in either case. Overall, our theory explains the intertwined mechanics of the cell spreading, migration speed and direction in the presence of the molecular adhesion reinforcement mechanism. </p>
A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain
ClinicalTrials.gov study NCT02308020. IPD Sharing: YES. Countries: 9. Publications: 1.
Data from: Integrative experimental/computational approach establishes active cellular protrusion as the primary driving force of phagocytic spreading by immune cells
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A multiscale theory for spreading and migration of adhesion-reinforced mesenchymal cells
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Center or Periphery? Modeling the Effects of Focal Adhesion Placement during Cell Spreading
<p>All data associate with paper Center or <em>Periphery? Modeling the Effects of Focal Adhesion Placement during Cell Spreading</em> by Magdalena Stolarska and Aravind Rammohan</p>
Sentinel Lymph Node Mapping in Detecting Cancer That Has Spread to Lymph Nodes in Patients With Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT00089310. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study of Subcutaneous Nivolumab Versus Intravenous Nivolumab in Participants With Previously Treated Clear Cell Renal Cell Carcinoma That is Advanced or Has Spread
ClinicalTrials.gov study NCT04810078. IPD Sharing: Not stated. Countries: 17. Publications: 0.
Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study
ClinicalTrials.gov study NCT04071223. IPD Sharing: YES. Countries: 1. Publications: 1.
Photodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the Pleura
ClinicalTrials.gov study NCT00601848. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of Cabozantinib and Nivolumab With Radiation Therapy for People With Renal Cell Carcinoma That Has Spread to the Brain
ClinicalTrials.gov study NCT06132945. IPD Sharing: YES. Countries: 1. Publications: 0.
HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread
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TET1 is a maintenance DNA demethylase that prevents methylation spreading in adult cells [RNA-seq]
GEO Series GSE49833. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
TET1 is a maintenance DNA demethylase that prevents methylation spreading in adult cells [MeDIP-Seq]
GEO Series GSE44036. Homo sapiens. 8 samples. Type: Methylation profiling by high throughput sequencing.
TET1 is a maintenance DNA demethylase that prevents methylation spreading in adult cells [DREAM]
GEO Series GSE44038. Homo sapiens. 4 samples. Type: Methylation profiling by high throughput sequencing.
UCPVax, a CD4 helper peptide vaccine induces polyfunctional Th1 cells, antibody response and epitope spreading to improve antitumor immunity [scRNA-seq]
GEO Series GSE271543. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Clonal spreading of tumor-infiltrating T cells underlies the durable antitumor effects of PD-1 blockade and anti-CD4 monoclonal antibody: Bulk TCR sequencing
GEO Series GSE216795. Mus musculus. 100 samples. Type: Other.
Microenvironmental Th9- and Th17-lymphocytes induce epithelial-mesenchymal transition in lung cancer cells, thereby promoting metastatic spreading
GEO Series GSE145186. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Hofbauer cells spread Listeria monocytogenes among placental cells and undergo pro-inflammatory reprogramming while retaining production of tolerogenic factors
GEO Series GSE174689. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
UCPVax, a CD4 helper peptide vaccine induces polyfunctional Th1 cells, antibody response and epitope spreading to improve antitumor immunity [TCR-seq]
GEO Series GSE271545. Homo sapiens. 10 samples. Type: Other.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.