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70 results for “Clinical trials (cancer treatment)”
Data for article "Personal approach for cancer treatment: a meta-analysis of Phase II Clinical trials"
<p>We conducted systematic review and meta-analysis to provide a comprehensive overview of outcomes in patients who underwent personalized genomics-based versus non-personalized treatment in oncology. The PubMed searches detected 803 studies based on phase II clinical trials’ results published from 2010 to 2021. We selected 50 studies, having 81 arms and 6536 patients for the analysis. We compared Response Rate (RR), medians and 1-year rates of Overall Survival (OS) and Progression-Free Survival (PFS) between genomics-based personalized and non-personalized arms. This repository contains final dataset (Dataset file) and t<span lang="EN-US">he information on 803 studies identified in the literature search (803 studies description file)</span>. </p> <p>The searches, study selection, data extraction and synthesis were performed in accordance to PRISMA (preferred reporting items for systematic review and meta-analysis) guidelines. The research protocol was registered in PROSPERO (International prospective register of systematic reviews, <a href="https://www.crd.york.ac.uk/PROSPERO" rel="nofollow">https://www.crd.york.ac.uk/PROSPERO</a>), record ID CRD42024504021. </p> <p>We performed proportional meta-analysis using the RStudio program, utilizing the R programming language and packages "meta", "metafor," and "tidyverse", the code is available at github: https://github.com/MikhailPot/PreciseOnco_meta-analysis </p>
Efficacy of Delayed Coloanal Anastomosis for Medium and Lower Rectum Cancer Treatment. Phase 2 Clinical Trial (CASCADOR)
ClinicalTrials.gov study NCT01876901. IPD Sharing: NO. Countries: 1. Publications: 1.
Clinical Trial of Lurbinectedin (PM01183)/Doxorubicin Versus CAV or Topotecan as Treatment in Patients With Small-Cell Lung Cancer
ClinicalTrials.gov study NCT02566993. IPD Sharing: Not stated. Countries: 20. Publications: 1.
A Clinical Trial to Assess the Safety of 0.005 % Estriol Vaginal Gel in Hormone Receptor-Positive Postmenopausal Women With Early Stage Breast Cancer in Treatment With Aromatase Inhibitor in the Adjuv
ClinicalTrials.gov study NCT02413008. IPD Sharing: Not stated. Countries: 2. Publications: 1.
A Clinical Trial Comparing Staged Turnbull-Cutait Pull-through Anastomosis With Direct Anastomosis Plus Prophylactic Ileostomy in the Treatment of Low Rectal Cancer After Internal Sphincter Resection
ClinicalTrials.gov study NCT06662643. IPD Sharing: YES. Countries: 1. Publications: 12.
Bone Mineral Density in Postmenopausal Women With Primary Breast Cancer Who Are Receiving Treatment on Clinical Trial
ClinicalTrials.gov study NCT00354302. IPD Sharing: NO. Countries: 1. Publications: 1.
A Phase II Clinical Trial of Fruquintinib as Third Line Treatment in Advanced Pancreatic Cancer
ClinicalTrials.gov study NCT05257122. IPD Sharing: NO. Countries: 1. Publications: 4.
Selective Axillary Lymph Node Dissection Vs Complete Axillary Dissection: A Randomised Clinical Trial to Assess the Prevention of Lymphedema in Breast Cancer Treatment
ClinicalTrials.gov study NCT03083314. IPD Sharing: NO. Countries: 1. Publications: 7.
Patient, Physician, and Nurse Factors Associated With Entry Onto Clinical Trials and Finishing Treatment in Patients With Primary or Recurrent Uterine, Endometrial, or Cervical Cancer
ClinicalTrials.gov study NCT01098630. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Anastrozole Adjuvant Trial - Study of Anastrozole Compared to NOLVADEX (Tamoxifen Citrate) for Adjuvant Treatment of Early Breast Cancer Clinical Studies), Adjunct Cytotoxic Chemotherapy and Malignant
ClinicalTrials.gov study NCT06154590. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Bone Density and Bone Loss in Postmenopausal Women With Breast Cancer Receiving Treatment in Clinical Trial IBCSG-1-98
ClinicalTrials.gov study NCT00369850. IPD Sharing: Not stated. Countries: 8. Publications: 1.
A Single-arm, Phase Ⅱ Clinical Trial of Anlotinib Hydrochloride Combined With Irinotecan or Docetaxel for Second Line Treatment of Nonsensitive Relapsed Small-cell Lung Cancer
ClinicalTrials.gov study NCT04757779. IPD Sharing: NO. Countries: 1. Publications: 1.
Clinical Trial of Qizhu Yuling Prescription in the Prevention and Treatment of Esophagus Cancer
ClinicalTrials.gov study NCT05626309. IPD Sharing: YES. Countries: 1. Publications: 1.
A Randomized Controlled Clinical Trial Comparing Oncological Results and Functional Recovery Between Laparoscopic and Open Method for the Treatment of Advanced Rectal Cancer After Concurrent Chemoradi
ClinicalTrials.gov study NCT00601549. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Clinical Trial of the Impact of Treatment Consultation Recordings on Cancer Patient Outcomes
ClinicalTrials.gov study NCT01866228. IPD Sharing: NO. Countries: 1. Publications: 1.
Clinical Trial of Yiqi Wenyang Jiedu Prescription in the Prevention and Treatment of Postoperative Metastasis and Recurrence of Gastric Cancer
ClinicalTrials.gov study NCT05229809. IPD Sharing: YES. Countries: 1. Publications: 1.
A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has S
ClinicalTrials.gov study NCT05568095. IPD Sharing: YES. Countries: 29. Publications: 0.
Disitamab Vedotin + Pyrotinib Versus THP in the First-line Treatment for HER2+ Advanced Breast Cancer Clinical Trial
ClinicalTrials.gov study NCT06278870. IPD Sharing: NO. Countries: 1. Publications: 13.
K-001 Treatment of Advanced Pancreatic Cancer: Clinical Trial of Monotherapy's Tolerability
ClinicalTrials.gov study NCT02720666. IPD Sharing: NO. Countries: 1. Publications: 1.
ProTarget - A Danish Nationwide Clinical Trial on Targeted Cancer Treatment Based on Genomic Profiling
ClinicalTrials.gov study NCT04341181. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.