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32 results for “Coca”

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zenodo40/100

Dataset: Coca-Cola Consolidated, Inc. (COKE) Stock Performance

This dataset provides historical stock market performance data for specific companies. It enables users to analyze and understand the past trends and fluctuations in stock prices over time. This information can be utilized for various purposes such as investment analysis, financial research, and market trend forecasting.

opencc-zeroJun 2024View details →
zenodo40/100

Dataset: Coca-Cola Europacific Partners PLC (CCEP) Stock Performance

This dataset provides historical stock market performance data for specific companies. It enables users to analyze and understand the past trends and fluctuations in stock prices over time. This information can be utilized for various purposes such as investment analysis, financial research, and market trend forecasting.

opencc-zeroJun 2024View details →
zenodo40/100

Dataset: The Coca-Cola Company (KO) Stock Performance

This dataset provides historical stock market performance data for specific companies. It enables users to analyze and understand the past trends and fluctuations in stock prices over time. This information can be utilized for various purposes such as investment analysis, financial research, and market trend forecasting.

opencc-zeroJun 2024View details →
zenodo40/100

Colombia. Justicia. Drogas. Municipal. Aspersión Aérea Coca. 2000 2011

<p>Colombia. Justicia. Drogas. Municipal. Aspersi&oacute;n A&eacute;rea Coca. 2000 2011</p>

opencc-by-4.0Jul 2023View details →
dryad36/100

The origins of coca: museum genomics reveals multiple independent domestications from progenitor Erythroxylum gracilipes

<p>Coca is the natural source of cocaine as well as a sacred and medicinal plant farmed by South American Amerindians and mestizos. The coca crop comprises four closely related varieties classified into two species (Amazonian and Huánuco varieties<i> </i>within <i>Erythroxylum coca</i> Lam., and Colombian and Trujillo varieties within<i> E. novogranatense </i>(D.Morris) Hieron.) but our understanding of their wild progenitor(s) and origins remains rudimentary. In this study we use genomic data from natural history collections to estimate the geographic origins and genetic diversity of this economically and culturally important crop in the context of its wild relatives. Our phylogeographic analyses clearly demonstrate the four varieties of coca comprise two or three exclusive groups nested within the diverse lineages of the widespread, wild species <i>E. gracilipes</i>; establishing a new and robust hypothesis of domestication wherein coca originated two or three times from this wild progenitor. The Colombian and Trujillo coca varieties are descended from a single, ancient domestication event in northwestern South America. Huánuco coca was domesticated more recently, possibly in southeastern Peru. Amazonian coca either shares a common domesticated ancestor with Huánuco coca, or it was the product of a third and most recent independent domestication event in the western Amazon basin. This chronology of coca domestication reveals different Holocene peoples in South America were able to independently transform the same natural resource to serve their needs; in this case, a workaday stimulant.</p>

opencc-zeroSep 2020View details →
dryad36/100

Data from: Hepatic steatosis induced by nicotine plus Coca-Cola™ is prevented by nicotinamide riboside (NR)

<p><strong>Introduction.</strong> Cigarettes containing nicotine (Nic) are a risk factor for the development of cardiovascular and metabolic diseases. We reported that Nic delivered via injections or e-cigarette vapor led to hepatic steatosis in mice fed with a high-fat diet. High-fructose corn syrup (HFCS) is the main sweetener in sugar-sweetened beverages (SSBs) in the US. Increased consumption of SSBs with HFCS is associated with increased risks of non-alcoholic fatty liver disease (NAFLD). Nicotinamide riboside (NR) increases mitochondrial nicotinamide adenine dinucleotide (NAD<sup>+</sup>) and protects mice against hepatic steatosis. This study evaluated if Nic plus Coca-Cola™ (Coke) with HFCS can cause hepatic steatosis and that can be protected by NR.</p> <p><strong>Methods.</strong> C57BL6 mice received twice daily intraperitoneal (IP) injections of Nic or saline and were given Coke (HFCS), or Coke with sugar, and NR supplementation for 10 weeks.</p> <p><strong>Results.</strong> Our results show that Nic+Coke caused increased caloric intake and induced hepatic steatosis, and the addition of NR prevented these changes. Western blot analysis showed lipogenesis markers were activated (increased cleavage of the sterol regulatory element-binding protein 1 [SREBP1c] and reduction of phospho-Acetyl-CoA Carboxylase [p-ACC]) in the Nic+Coke compared to the Sal+Water group. The hepatic detrimental effects of Nic+Coke were mediated by decreased NAD<sup>+</sup> signaling, increased oxidative stress, and mitochondrial damage. NR reduced oxidative stress and prevented mitochondrial damage by restoring protein levels of Sirtuin1 (Sirt1) and peroxisome proliferator-activated receptor coactivator 1-alpha (PGC1a) signaling.</p> <p><strong>Discussion.</strong> We conclude that Nic+Coke has an additive effect on producing hepatic steatosis, and NR is protective. This study suggests concern for the development of NAFLD in subjects who consume nicotine and drink SSBs with HFCS.</p>

opencc-zeroApr 2024View details →
dryad36/100

The origins of coca: museum genomics reveals multiple independent domestications from progenitor Erythroxylum gracilipes

Open the record for dataset details and reuse information.

publicOct 2020View details →
dryad36/100

Data from: Hepatic steatosis induced by nicotine plus Coca-Cola™ is prevented by nicotinamide riboside (NR)

Open the record for dataset details and reuse information.

publicApr 2024View details →
dryad32/100

Data from: Phylogenetic inference in section Archerythroxylum informs taxonomy, biogeography, and the domestication of coca (Erythroxylum species)

This investigation establishes the first sequence-based phylogenetic hypothesis of species relationships in the Coca family (Erythroxylaceae). We focused our phylogenomic inference on the largest taxonomic section in the genus Erythroxylum (Archerythroxylum O. E. Schulz) using concatenation and gene tree reconciliation methods from hybridization-based target capture of 427 genes. We show that Neotropical Erythroxylum are monophyletic within the Paleotropical lineages, yet Archerythroxylum and all of the other taxonomic sections from which we sampled multiple species lack monophyly. We mapped phytogeographic states onto the tree and found some concordance between these regions and clades. The wild species E. gracilipes and E. cataractarum are most closely related to the cultivated E. coca and E. novogranatense but relationships within this "coca" clade remain equivocal, suggesting a more complicated origin than Plowman's single-domestication hypothesis. Our results point to the difficulty of morphology-based intrageneric classification in this clade and highlight the importance of integrative taxonomy in future systematic revisions. In compliance with data protection regulations, please contact the publication office if you would like to have your personal information removed from the database.

opencc-zeroDec 2018View details →
zenodo32/100

Erythroxylum coca decontaminated_FSCR

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opencc-by-4.0Oct 2021View details →
zenodo32/100

Erythroxylum coca decontaminated gx

<p>.</p>

opencc-by-4.0Nov 2021View details →
zenodo32/100

Erythroxylum coca Zanfona pass 1

<p>.</p>

opencc-by-4.0Nov 2021View details →
zenodo32/100

Erythroxylum coca zanfona pass 3

<p>Reference:&nbsp; Erythroxylum novo in 2K fragments.</p>

opencc-by-4.0Dec 2021View details →
zenodo32/100

Erythoxylum coca zanfona pass 1

<p>Reference:</p> <p>Erythroxylum novo preassembly.</p>

opencc-by-4.0Nov 2021View details →
zenodo32/100

Erythroxylum coca zanfona pass 2

<p>.</p>

opencc-by-4.0Nov 2021View details →
zenodo32/100

Erythroxylum coca zanfona pass 3

<p>.</p>

opencc-by-4.0Dec 2021View details →
zenodo32/100

Erythroxylum coca zanfona pass 1

<p>Reference: Erythroxylum novo.&nbsp;&nbsp;</p> <p>Inferred gap lengths.</p>

opencc-by-4.0Nov 2021View details →
zenodo32/100

Erythroxylum coca zanfona 1

<p>.</p>

opencc-by-4.0Jul 2022View details →
zenodo32/100

Erythroxylum coca SPAdes preassembly

<p>.</p>

opencc-by-4.0Aug 2021View details →
ClinicalTrials.gov32/100

Coca-Cola Zero (®) Consumption on Night-call Inpatient Course and Mortality

ClinicalTrials.gov study NCT06155981. IPD Sharing: NO. Countries: 1. Publications: 1.

closedIPD-NOFeb 2026View details →

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International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

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OpenNeuro

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Last verified 2026-04-29Open record