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28 results for “Complete revascularization”
Raw Data for the article: Clinical Insights to Complete and Incomplete Surgical Revascularization in Atrial Fibrillation and Multivessel Coronary Disease
<p><strong>Objectives: </strong>Although endorsed by international guidelines, complete revascularization (CR) with Coronary Artery Bypass Grafting (CABG) remains underused. In higher-risk patients such as those with pre-operative atrial fibrillation (AF), the effects of CR are not well studied.</p> <p><strong>Methods: </strong>We analyzed patients' data from the HEIST (HEart surgery In AF and Supraventricular Tachycardia) registry. Between 2012 and 2020 we identified 4770 patients with pre-operative AF and multivessel coronary artery disease who underwent isolated CABG. We divided the cohort according to the completeness of the revascularization and used propensity score matching (PSM) to minimize differences between baseline characteristics. The primary endpoint was all-cause mortality.</p> <p><strong>Results: </strong>Median follow-up was 4.7 years [interquartile range (IQR) 2.3-6.9]. PSM resulted in 1,009 pairs of complete and incomplete revascularization. Number of distal anastomoses varied, accounting for 3.0 + -0.6 vs. 1.7 + -0.6, respectively. Although early (< 24 h) and 30-day post-operative mortalities were not statistically different between non-CR and CR patients [Odds Ratio (OR) and 95% Confidence Intervals (CIs): 1.34 (0.46-3.86); <em>P</em> = 0.593, Hazard Ratio (HR) and 95% CIs: 0.88 (0.59-1.32); <em>P</em> = 0.542, respectively] the long term mortality was nearly 20% lower in the CR cohort [HR (95% CIs) 0.83 (0.71-0.96); <em>P</em> = 0.011]. This benefit was sustained throughout subgroup analyses, yet most accentuated in low-risk patients (younger i.e., < 70 year old, with a EuroSCORE II < 2%, non-diabetic) and when off-pump CABG was performed.</p> <p><strong>Conclusion: </strong>Complete revascularization in patients with pre-operative AF is safe and associated with improved survival. Particular survival benefit with CR was observed in low-risk patients undergoing off-pump CABG.</p>
Ffr-gUidance for compLete Non-cuLprit REVASCularization
ClinicalTrials.gov study NCT02862119. IPD Sharing: NO. Countries: 1. Publications: 3.
Primary PCI in Patients With ST-elevation Myocardial Infarction and Multivessel Disease: Treatment of Culprit Lesion Only or Complete Revascularization
ClinicalTrials.gov study NCT01960933. IPD Sharing: Not stated. Countries: 1. Publications: 13.
Direct Complete Versus Staged Complete Revascularization in Patients Presenting With Acute Coronary Syndromes and Multivessel Disease
ClinicalTrials.gov study NCT03621501. IPD Sharing: NO. Countries: 1. Publications: 22.
In-hospital Versus After-discharge Complete Revascularization
ClinicalTrials.gov study NCT04743154. IPD Sharing: NO. Countries: 1. Publications: 16.
Timing of Complete Revascularization in Patients With ST-segment Elevation Myocardial Infarction And Multivessel Disease
ClinicalTrials.gov study NCT05231226. IPD Sharing: NO. Countries: 1. Publications: 13.
Evaluation of a Modified Anti-Platelet Therapy Associated With Low-dose DES Firehawk in Acute Myocardial Infarction Patients Treated With Complete Revascularization Strategy
ClinicalTrials.gov study NCT04753749. IPD Sharing: NO. Countries: 6. Publications: 2.
Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI
ClinicalTrials.gov study NCT05786131. IPD Sharing: NO. Countries: 2. Publications: 1.
Complete vs Culprit-only Revascularization to Treat Multi-vessel Disease After Early PCI for STEMI
ClinicalTrials.gov study NCT01740479. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
COMPLETE: International Acute Ischemic Stroke Registry With the Penumbra System Aspiration Including the 3D Revascularization Device
ClinicalTrials.gov study NCT03464565. IPD Sharing: Not stated. Countries: 6. Publications: 3.
The Use Of FFR Guided PCI Versus Complete Revascularization and Treatment Of Infarct Related Artery Only In Patients With STEMI
ClinicalTrials.gov study NCT02637440. IPD Sharing: Not stated. Countries: 1. Publications: 3.
FFR Driven Complete Revascularization Versus Usual Care in NSTEMI Patients and Multivessel Disease
ClinicalTrials.gov study NCT03562572. IPD Sharing: UNDECIDED. Countries: 3. Publications: 1.
Complete Revascularization Via Inferior Part-sternotomy
ClinicalTrials.gov study NCT05835167. IPD Sharing: UNDECIDED. Countries: 0. Publications: 7.
Complete Lesion Versus Culprit Lesion Revascularization
ClinicalTrials.gov study NCT01180218. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Complete Infarct Related Artery Revascularization in Acute Myocardial Infarction
ClinicalTrials.gov study NCT01642784. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Feasibility and Outcomes of Complete Coronary Revascularization Using BVS in All-comer Patients With Angina
ClinicalTrials.gov study NCT02707783. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Coronary Bypass Surgery Trial: Complete Arterial Revascularization and Conventional Coronary Artery Surgery
ClinicalTrials.gov study NCT00317265. IPD Sharing: Not stated. Countries: 7. Publications: 0.
Efficacy of Immediate Versus Staged Complete Revascularization in Patients With NSTE-ACS and Multivessel Disease (FUTURE II)
ClinicalTrials.gov study NCT07343076. IPD Sharing: YES. Countries: 0. Publications: 0.
PRospective Evaluation of Complete Revascularization in Patients With multiveSsel Disease Excluding chroNic Total Occlusions
ClinicalTrials.gov study NCT05230446. IPD Sharing: Not stated. Countries: 1. Publications: 0.
FIT (Fast Infarction Treatment): Complete Revascularization During Primary Percutaneous Coronary Intervention (PCI) Can be Achieved Safely With an Improved Clinical Outcome During the Indexed Hospital
ClinicalTrials.gov study NCT01160900. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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