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6 results for “Corynebacterium diphtheriae”
Proteome analysis of Corynebacterium diphtheriae - macrophage interaction
<p>Contact of <em>Corynebacterium diphtheriae</em> with macrophages induce adaptations on both bacterial and cellular sides. Using an experimental design involving gentamicin protection and liquid chromagraphy followed by mass-spectrometry, a multi-species proteomic dataset was analyzed at different time points of the infection assay. Several previously undescribed <em>Corynebacterium </em>proteins were differentially regulated, as well as key macrophage components of the phagolysosome. Overall, Bacteria responded to phagocytosis by changes in DNA repair, transcription and cell wall synthesis proteins, while macrophages showed changes in components of the innate immune system.</p> <p>This dataset consists of:</p> <ul> <li> Raw protein abundance data for Macrophage THP-1 cells (M0) obtained by LC-MS/MS followed by peptide sequencing using Proteome Discoverer (ThermoFisher) -see .zip folder.</li> <li>Raw protein abundance data for Macrophage <em>C. diphtheriae </em>ISS3319 (CD) obtained by LC-MS/MS followed by peptide sequencing using Proteome Discoverer (ThermoFisher) - see .zip folder.</li> <li>Differential protein abundance analysis for CD and M0 using LIMMA. </li> <li>Data underlying the growth curves observed in CD in RPMI + 10% FBS conditions (infection assay conditions).</li> <li>BLASTP searches, PFAM clans, and InterPro annotations for CD.</li> <li>STRING-based PPI network (baseline) and APSPs between differentially abundant proteins in CD. </li> <li>Related R scripts.</li> </ul>
Identification of Corynebacterium diphtheriae manganese and MntR regulated genes
GEO Series GSE173960. Corynebacterium diphtheriae. 12 samples. Type: Expression profiling by array.
Identification of zinc and Zur-regulated genes in Corynebacterium diphtheriae
GEO Series GSE131485. Corynebacterium diphtheriae NCTC 13129; Corynebacterium diphtheriae. 9 samples. Type: Expression profiling by array.
RNA-seq of pathogen Corynebacterium diphtheriae NCTC 13129 provides detailed insights into transcriptional landscape
GEO Series GSE98202. Corynebacterium diphtheriae NCTC 13129. 7 samples. Type: Expression profiling by high throughput sequencing.
Ribonuclease J modulates cell shape, exotoxin production, and virulence in Corynebacterium diphtheriae
GEO Series GSE165533. Corynebacterium diphtheriae. 6 samples. Type: Expression profiling by high throughput sequencing.
Identification of genes differentially regulated in Corynebacterium diphtheriae by iron and DtxR
GEO Series GSE119621. Corynebacterium diphtheriae NCTC 13129; Corynebacterium diphtheriae. 9 samples. Type: Expression profiling by array.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.