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61 results for “Corynebacterium glutamicum”
A compendium of expression profiles for Corynebacterium glutamicum
<p><em>Corynebacterium glutamicum</em> is the major host for the industrial production of amino acids and has become one of the best studied model organisms in microbial biotechnology. Rational strain construction has led to an improvement of producer strains and to a variety of novel producer strains with a broad substrate and product spectrum. A key factor for the success of these approaches is detailed knowledge of transcriptional regulation in <em>C. glutamicum</em>. Here, we present a large compendium of 927 manually curated microarray-based transcriptional profiles for wild-type and engineered strains detecting genome-wide expression changes of the 3,047 annotated genes in response to various environmental conditions or in response to genetic modifications. The replicates within the 927 experiments were combined to 304 microarray sets ordered into six categories that were used for differential gene expression analysis. Hierarchical clustering confirmed that no outliers were present in the sets. The compendium provides a valuable resource for future fundamental and applied research with <em>C. glutamicum</em> and contributes to a systemic understanding of this microbial cell factory.</p>
Raw Raman data of Mycobacterium bovis BCG, Rhodococcus erythropolis, & Corynebacterium glutamicum
<p>Even in the face of the COVID-19 pandemic, Tuberculosis (TB) continues to be a major public health problem and the 2nd biggest infectious cause of death worldwide. There is, therefore, an urgent need to develop effective TB diagnostic methods, which are cheap, portable, sensitive and specific. Raman spectroscopy is a potential spectroscopic technique for this purpose, however, so far, research efforts have focused primarily on the characterisation of Mycobacterium tuberculosis and other Mycobacteria, neglecting bacteria within the microbiome and thus, failing to consider the bigger picture. It is paramount to characterise relevant Mycobacteriales and develop suitable analytical tools to discriminate them from each other. Herein, through the combined use of Raman spectroscopy and the self-optimising Kohonen index network and further multivariate tools, we have successfully undertaken the spectral analysis of Mycobacterium bovis BCG, Corynebacterium glutamicum and Rhodoccocus erythropolis. This has led to development of a useful tool set, which can readily discern spectral differences between these three closely related bacteria as well as generate a unique spectral barcode for each species. Further optimisation and refinement of the developed method will enable its application to other bacteria inhabiting the microbiome and ultimately lead to advanced diagnostic technologies, which can save many lives. </p>
Raw Raman data of Mycobacterium bovis BCG, Rhodococcus erythropolis, & Corynebacterium glutamicum
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Transcriptional response of Corynebacterium glutamicum C1 to 3 mM indole-alanine dipeptide
GEO Series GSE159888. Corynebacterium glutamicum. 6 samples. Type: Expression profiling by high throughput sequencing.
Metabolic engineering of Corynebacterium glutamicum for L-arginine production
GEO Series GSE52737. Corynebacterium glutamicum; Corynebacterium glutamicum ATCC 13032. 4 samples. Type: Expression profiling by array.
Transcriptional response of Corynebacterium glutamicum ATCC 13032 to 2.5 mM indole
GEO Series GSE159887. Corynebacterium glutamicum. 2 samples. Type: Expression profiling by high throughput sequencing.
Comparative analysis on Corynebacterium glutamicum transcriptome in response to the change of dissolved oxygen in bioreactor
GEO Series GSE77502. Corynebacterium glutamicum. 9 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome analyses of the Corynebacterium glutamicum strains adapted to supraoptimal growth temperatures
GEO Series GSE64654. Corynebacterium glutamicum; Corynebacterium glutamicum R. 16 samples. Type: Expression profiling by array.
Gene expression patterns of pediocin-producing Corynebacterium glutamicum strains
GEO Series GSE220713. Corynebacterium glutamicum. 6 samples. Type: Expression profiling by array.
Global transcriptomic analysis of the response of Corynebacterium glutamicum to vanillin
GEO Series GSE85949. Corynebacterium glutamicum ATCC 13032. 4 samples. Type: Expression profiling by array.
A new metabolic route for the production of gamma-aminobutyric acid in Corynebacterium glutamicum
GEO Series GSE74258. Corynebacterium glutamicum; Corynebacterium glutamicum ATCC 13032. 2 samples. Type: Expression profiling by array.
A compendium of expression profiles for Corynebacterium glutamicum ATCC13032 [with raw data]
GEO Series GSE169361. Corynebacterium glutamicum; Corynebacterium glutamicum ATCC 13032. 927 samples. Type: Expression profiling by array.
Adaptive evolution of Corynebacterium glutamicum resistant to oxidative stress and its global gene expression profiling
GEO Series GSE41232. Corynebacterium glutamicum ATCC 13032. 3 samples. Type: Expression profiling by high throughput sequencing.
Identification of two mutations increasing the methanol tolerance of Corynebacterium glutamicum
GEO Series GSE71590. Corynebacterium glutamicum; Corynebacterium glutamicum ATCC 13032. 7 samples. Type: Expression profiling by array.
Regulation of the pstSCAB operon in Corynebacterium glutamicum by the regulator of acetate metabolism RamB
GEO Series GSE67012. Corynebacterium glutamicum ATCC 13032. 2 samples. Type: Expression profiling by array.
Engineering Corynebacterium glutamicum for fast production of lysine and pipecolic acid
GEO Series GSE79690. Corynebacterium glutamicum; Corynebacterium glutamicum ATCC 13032. 4 samples. Type: Expression profiling by array.
Rational engineering of Corynebacterium glutamicum for the production of the dicarboxylic acid glutarate
GEO Series GSE117175. Corynebacterium glutamicum; Corynebacterium glutamicum ATCC 13032. 3 samples. Type: Expression profiling by array.
Identification of a gene cluster involved in the utilization of phenylpropanoids in Corynebacterium glutamicum [set1]
GEO Series GSE69412. Gluconobacter oxydans; Escherichia coli; Corynebacterium glutamicum; Bacillus subtilis subsp. subtilis str. 168. 2 samples. Type: Expression profiling by array.
Pupylated proteins in Corynebacterium glutamicum revealed by MudPIT analysis
GEO Series GSE48038. Gluconobacter oxydans; Corynebacterium glutamicum ATCC 13032; Escherichia coli; Corynebacterium glutamicum; Bacillus subtilis subsp. subtilis str. 168. 6 samples. Type: Expression profiling by array.
Transcriptome analysis of Corynebacterium glutamicum ΔtrpP
GEO Series GSE272128. Gluconobacter oxydans; Bacillus subtilis; Corynebacterium glutamicum; Escherichia coli; Pseudomonas putida KT2440. 4 samples. Type: Expression profiling by array.
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