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23 results for “Cryptochrome”
Control of odor sensation by light and cryptochrome in the Drosophila antenna
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Raw data for the article: A Cryptochrome adopts distinct moon- and sunlight states and functions as sun- versus moonlight interpreter in monthly oscillator entrainment
<p>The moon's monthly cycle synchronizes reproduction in countless marine organisms. The mass-spawning bristle worm Platynereis dumerilii uses an endogenous monthly oscillator to phase reproduction to specific days. Classical work showed that this oscillator is set by full moon. But how do organisms recognize such a specific moon phase? We uncover that the light receptor L-Cryptochrome (L-Cry) is able to discriminate between different moonlight durations, as well as between sun- and moonlight. Consistent with L-Cry's function as light valence interpreter, its genetic loss leads to a faster re-entrainment under artificially strong nocturnal light. This suggests that L-Cry blocks "wrong" light from impacting on the monthly oscillator. A biochemical characterization of purified L-Cry protein, exposed to naturalistic sun- or moonlight, reveals the formation of distinct sun- and moonlight states characterized by different photoreduction- and recovery kinetics of L-Cry's co-factor Flavin Adenine Dinucleotide. In vivo, L-Cry's sun- versus moonlight states correlate with distinct sub-cellular localizations, indicating different signalling. In contrast, r-Opsin1, the most abundant ocular opsin, is not required for monthly oscillator entrainment. Our work reveals a new concept for correct moonlight interpretation involving a "valence interpreter" that provides entraining photoreceptor(s) with light source and moon phase information. These findings advance our mechanistic understanding of a fundamental biological phenomenon: moon-controlled monthly timing. Such level of understanding is also an essential prerequisite to tackle anthropogenic threats on marine ecology.</p>
Dataset for: A marine cryptochrome with an inverse photo-oligomerization mechanism
<p>Raw data for all sequence analysis, SEC runs, MD simulations, and UV/Vis absorbance readings supporting the findings of the study 'A marine cryptochrome with an inverse photo-oligomerization mechanism'</p>
Raw data for the article: A Cryptochrome adopts distinct moon- and sunlight states and functions as sun- versus moonlight interpreter in monthly oscillator entrainment
Open the record for dataset details and reuse information.
Cryptochrome 1 regulates growth and development in Brassica through alteration in the expression of genes involved in light, phytohormone and stress signalling
GEO Series GSE26797. Brassica napus; Brassica juncea. 4 samples. Type: Expression profiling by array.
Duper is a Cryptochrome 1 null mutation in Syrian hamsters
GEO Series GSE184205. Mesocricetus auratus. 6 samples. Type: Expression profiling by high throughput sequencing.
Cryptochromes mediate rhythmic repression of the glucocorticoid receptor
GEO Series GSE24469. Mus musculus. 12 samples. Type: Expression profiling by array.
Circadian Cryptochrome 1 (CRY1) Rhythmically Modulates the DNA Damage Response [RNA-seq]
GEO Series GSE144961. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Circadian Cryptochrome 1 (CRY1) Rhythmically Modulates the DNA Damage Response [ChIP-seq]
GEO Series GSE144960. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Molecular characterization of a cryptochrome in Neurospora crassa
GEO Series GSE14909. Neurospora crassa. 12 samples. Type: Expression profiling by array.
Cryptochromes-mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved signaling mechanism
GEO Series GSE124388. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
GEO Series GSE216975. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
A repeatedly evolved mutation in Cryptochrome-1 of subterranean animals alters behavioral and molecular circadian rhythms
GEO Series GSE277611. Mus musculus. 85 samples. Type: Expression profiling by high throughput sequencing.
Cryptochromes interact directly with PIFs to control plant growth in limiting blue light
GEO Series GSE59699. Arabidopsis thaliana. 36 samples. Type: Expression profiling by high throughput sequencing.
Cryptochromes interact directly with PIFs to control plant growth in limiting blue light
GEO Series GSE68193. Arabidopsis thaliana. 13 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Cryptochrome 1 attenuates plant heat stress response by light-heat stress response signal pathways crosstalk in Arabidopsis
GEO Series GSE254813. Arabidopsis thaliana. 12 samples. Type: Expression profiling by high throughput sequencing.
Arabidopsis BIC1 inactivates CRY2 by suppressing the blue light-dependent cryptochrome dimerization
GEO Series GSE80350. Arabidopsis thaliana. 18 samples. Type: Expression profiling by high throughput sequencing.
Circadian Cryptochrome 1 (CRY1) Rhythmically Modulates the DNA Damage Response
GEO Series GSE144962. Homo sapiens. 11 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
The Influence of a Cryptochrome on the Gene Expression Profile in the Diatom Phaeodactylum tricornutum under Blue Light and in Darkness
GEO Series GSE95565. Phaeodactylum tricornutum. 15 samples. Type: Expression profiling by high throughput sequencing.
Co-condensation with photoexcited Cryptochromes facilitates MOS4-associated complex subunits 3A/3B to antagonize HY5 activities during photomorphogenesis in Arabidopsis
GEO Series GSE220945. Arabidopsis thaliana. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.