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ShareScore release 0.9.0
Dataset results
23 results for “Cultural property”
Raw Data for the article: Changes in the Transcriptome Profiles of Human Amnion-Derived Mesenchymal Stromal/Stem Cells Induced by Three-Dimensional Culture: A Potential Priming Strategy to Improve Their Properties
<p>Mesenchymal stromal/stem cells (MSCs) are believed to function in vivo as a homeostatic tool that shows therapeutic properties for tissue repair/regeneration. Conventionally, these cells are expanded in two-dimensional (2D) cultures, and, in that case, MSCs undergo genotypic/phenotypic changes resulting in a loss of their therapeutic capabilities. Moreover, several clinical trials using MSCs have shown controversial results with moderate/insufficient therapeutic responses. Different priming methods were tested to improve MSC effects, and three-dimensional (3D) culturing techniques were also examined. MSC spheroids display increased therapeutic properties, and, in this context, it is crucial to understand molecular changes underlying spheroid generation. To address these limitations, we performed RNA-seq on human amnion-derived MSCs (hAMSCs) cultured in both 2D and 3D conditions and examined the transcriptome changes associated with hAMSC spheroid formation. We found a large number of 3D culture-sensitive genes and identified selected genes related to 3D hAMSC therapeutic effects. In particular, we observed that these genes can regulate proliferation/differentiation, as well as immunomodulatory and angiogenic processes. We validated RNA-seq results by qRT-PCR and methylome analysis and investigation of secreted factors. Overall, our results showed that hAMSC spheroid culture represents a promising approach to cell-based therapy that could significantly impact hAMSC application in the field of regenerative medicine.</p>
Translation, cross-cultural adaptation, and evaluation of psychometric properties of cystic fibrosis stigma scale
<pre>Search database</pre>
Cross Cultural Adaptation and Psychometric Properties of Urdu Version of Fall Risk Questionnaire
ClinicalTrials.gov study NCT06687031. IPD Sharing: NO. Countries: 1. Publications: 6.
Translation, Cultural Adaptation and Psychometric Properties of Urdu Version of Upper Limb Functional Index Questionnaire in Patients With Upper Limb Musculoskeletal Disorders
ClinicalTrials.gov study NCT05088096. IPD Sharing: NO. Countries: 1. Publications: 1.
Laminin111-based defined culture promoting self-renewing human pluripotent stem cells with properties of the early post-implantation epiblast
GEO Series GSE206713. Homo sapiens. 35 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Integrated Transcriptomic and Metabolomic Analyses Reveal Distinct Energy Metabolic Signatures and Functional Properties of RPE Cells under Two Culture Conditions
GEO Series GSE318428. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Cultured alveolar basal cells differ in their transcriptome, but display similar characteristics and functional properties to airway basal cells
GEO Series GSE270495. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Laminin111-based defined culture promoting self-renewing human pluripotent stem cells exhibiting properties of early post-implantation epiblast cells [Bulk_RNA_Seq]
GEO Series GSE206708. Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.
Laminin111-based defined culture promoting self-renewing human pluripotent stem cells exhibiting properties of early post-implantation epiblast cells [LN_hPSC_RRBS]
GEO Series GSE206711. Homo sapiens. 16 samples. Type: Methylation profiling by high throughput sequencing.
Psychometric Properties and Cross-cultural Adaptation of the Turkish Version of Physcian Attitudes Toward Cardiac Rehabilitation and Referral Scale-Revised (PACRR-R)
ClinicalTrials.gov study NCT06356428. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Laminin111-based defined culture promoting self-renewing human pluripotent stem cells exhibiting properties of early post-implantation epiblast cells [LN_hPSC_SC]
GEO Series GSE206712. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Human Bone Marrow Stromal Cells cultured on polymer scaffolds with varied properties
GEO Series GSE50743. Homo sapiens. 72 samples. Type: Expression profiling by array.
Synthetic polymer based 3D culture improve naïve properties of human induced pluripotent stem cells
GEO Series GSE233565. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Single-cell dissection of Comma-1D cultures reveals cell populations with unique differentiation and transformation properties [scRNA-Seq]
GEO Series GSE182352. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Synthesis and Anticancer Properties of Water-Soluble Zinc Ionophore: Cell Culture and Xenograft Model
GEO Series GSE6972. Homo sapiens. 24 samples. Type: Expression profiling by array.
Single-cell dissection of Comma-1D cultures reveals cell populations with unique differentiation and transformation properties
GEO Series GSE182354. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
Single-cell dissection of Comma-1D cultures reveals cell populations with unique differentiation and transformation properties [bulk RNA-Seq]
GEO Series GSE182351. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Neural Stem/Progenitor Cell Properties of Glial Cells in the Adult Auditory Nerve [cultured auditory nerve cells]
GEO Series GSE65249. Mus musculus. 9 samples. Type: Expression profiling by array.
Distinctive Biological Properties Between Mesenchymal Stem Cells Spheroids and Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes in 3D Culture Systems.
GEO Series GSE247989. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Next generation seuquencing of 3D breast cancer cell culture in synthetic hydrogels presenting either a collagen mimic or laminin mimic with low and high mechanical properties
GEO Series GSE145696. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.