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Dataset results
68 results for “DRUG-RESISTANT EPILEPSY,”
Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy
ClinicalTrials.gov study NCT03373383. IPD Sharing: YES. Countries: 19. Publications: 2.
A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy
ClinicalTrials.gov study NCT03739840. IPD Sharing: YES. Countries: 28. Publications: 1.
Efficacy, Tolerability and Adherence of the Modified Atkins Diet on Drug-resistant Epilepsy
ClinicalTrials.gov study NCT03183076. IPD Sharing: NO. Countries: 1. Publications: 30.
PRediction of Vagal Nerve Stimulation EfficaCy In Drug-reSistant Epilepsy
ClinicalTrials.gov study NCT04935567. IPD Sharing: NO. Countries: 1. Publications: 1.
The Benefit and Safety of Older Generation Anti-Epileptic Drugs (AEDs) in Drug-Resistant Epilepsy Children
ClinicalTrials.gov study NCT05697614. IPD Sharing: NO. Countries: 1. Publications: 1.
Real-World Study of Magnetic Resonance-guided Laser Interstitial Thermal Therapy for Drug-resistant Epilepsy
ClinicalTrials.gov study NCT06341075. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
IF-MCT 16:8: Investigating the Influence of Intermittent Fasting With and Without MCTs in Patients With Drug-resistant Epilepsy
ClinicalTrials.gov study NCT06013761. IPD Sharing: NO. Countries: 1. Publications: 0.
Determinants of Adaptive Behavior Through the Vineland Scale in Pediatric Patients with Severe and Drug-resistant Epilepsy
ClinicalTrials.gov study NCT06832020. IPD Sharing: YES. Countries: 1. Publications: 8.
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
ClinicalTrials.gov study NCT05135091. IPD Sharing: NO. Countries: 1. Publications: 1.
Exploring the Characteristics of Epileptogenic Foci in Drug-Resistant Epilepsy Based on Multimodal Imaging Technology
ClinicalTrials.gov study NCT06557720. IPD Sharing: NO. Countries: 1. Publications: 6.
Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies
ClinicalTrials.gov study NCT02890641. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Recording "Fast Ripples" Using Microelectrodes During Stereo-encephalography in Patients With Drug-resistant Partial Epilepsy
ClinicalTrials.gov study NCT02491476. IPD Sharing: Not stated. Countries: 1. Publications: 9.
A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy
ClinicalTrials.gov study NCT06388707. IPD Sharing: NO. Countries: 1. Publications: 3.
Impact of Thermocoagulation During Invasive EEG Monitoring in Children With Focal Drug-resistant Epilepsies
ClinicalTrials.gov study NCT02886650. IPD Sharing: Not stated. Countries: 1. Publications: 0.
TDCs to Treat Drug-resistant Epilepsy
ClinicalTrials.gov study NCT05825274. IPD Sharing: YES. Countries: 1. Publications: 3.
Usefulness of Sodium MRI in the Presurgical Assessment of Drug-resistant Partial Epilepsy
ClinicalTrials.gov study NCT02304029. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epilepsy
ClinicalTrials.gov study NCT04782869. IPD Sharing: NO. Countries: 1. Publications: 0.
The Efficacy and Safety of Minocycline in the Treatment of Drug-resistant Epilepsy in NORSE Patients
ClinicalTrials.gov study NCT05958069. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Generalized polyspike train: an EEG biomarker of drug-resistant idiopathic generalized epilepsy
Objective: To identify clinical and EEG biomarkers of drug resistance in adults with idiopathic generalized epilepsy. Methods: We conducted a case-control study consisting of a discovery cohort and a replication cohort independently assessed at two different centres. In each centre patients with idiopathic generalized epilepsy phenotype and generalized spike-wave discharges on EEG were classified as drug-resistant or drug-responsive. EEG changes were classified into pre-defined patterns and compared between the two groups in the discovery cohort. Factors associated with drug resistance in multivariable analysis were tested in the replication cohort. Results: The discovery cohort included 85 patients (29% drug-resistant and 71% drug-responsive). Their median age at assessment was 32 years and 50.6% were female. Multivariable analysis showed that having higher number of seizure types (3 vs. 1: odds ratio [OR]= 31.1, 95% confidence interval [CI] 4.5-214, p<0.001; 3 vs. 2: OR=14.6, 95% CI: 2.3-93.1, p=0.004) and generalized polyspike train (burst of generalized rhythmic spikes lasting less than 1 second) during sleep were associated with drug resistance (OR=10.8, 95% CI: 2.4-49.4, p=0.002). When these factors were tested in the replication cohort of 80 patients (27.5% drug-resistant and 72.5% drug-responsive; 71.3% female; median age 27.5 years), the proportion of patients with generalized polyspike train during sleep was also higher in the drug-resistant group (OR=4.0, 95% CI: 1.35-11.8, p=0.012). Conclusion: Generalized polyspike train during sleep may be an EEG biomarker for drug resistance in adults with idiopathic generalized epilepsy.
The Effect of Probiotic Supplementation in Drug-resistant Epilepsy Patients
ClinicalTrials.gov study NCT03403907. IPD Sharing: NO. Countries: 0. Publications: 3.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.