Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
15
datasets available to search
ShareScore release 0.9.0
Dataset results
15 results for “Domoic acid”
Understanding the risks of co-exposures in a changing world: A case study of dual monitoring of the biotoxin domoic acid and Vibrio spp. in Pacific oyster
<div> <p><span>Assessing the co-occurrence of multiple health risk factors in coastal ecosystems is challenging due to the complexity of multi-factor interactions and limited availability simultaneously collected data. Understanding co-occurrence is particularly important for risk factors that may be associated with or occur in similar environmental conditions. In marine ecosystems, the co-occurrence of harmful algal bloom toxins and bacterial pathogens within the genus <em>Vibrio </em>may impact both ecosystem and human health. This study examined the co-occurrence of <em>Vibrio</em> spp. and domoic acid (DA) produced by the harmful algae <em>Pseudonitzschia</em> by 1) analyzing existing California Department of Public Health monitoring data for <em>V. parahaemolyticus</em> and DA in oysters; 2) and conducting a one-year seasonal monitoring of these risk factors across two Southern California embayments. Existing public health monitoring efforts in the state were robust for individual risk factors; however, it was difficult to evaluate the co-occurrence of these risk factors in oysters due to low number of co-monitoring instances between 2015 and 2020. Seasonal co-monitoring of that DA and <em>Vibrio</em> spp. (<em>V. vulnificus</em> or <em>V. parahaemolyticus</em>) at two embayments revealed the co-occurrence of these health risk factors in 35% of sampled oysters in most seasons. Interestingly, both the overall detection frequency and co-occurrence of these risk factors was considerably less frequent in water samples. These findings may in part suggest the slow depuration of <em>Vibrio </em>spp. and DA in oysters as residual levels may be retained. This study expanded our understanding of the simultaneous presence of DA and <em>Vibrio</em> spp. in bivalves and demonstrate the feasibility of co-monitoring different risk factors from the same sample. Individual programs monitoring for different risk factors from the same sample matrix may consider combining efforts to reduce cost, streamline the process, and better understand the prevalence of co-occurring health risk factors.</span></p> </div>
FIGURE 2. CMM-V-10108, a in A Miocene cetacean vertebra showing a partially healed longitudinal shear-compression fracture, possibly the result of domoic acid toxicity or failed predation
FIGURE 2. CMM-V-10108, a Miocene pathological cetacean vertebra associated with the one shown in Figures 5 and 6. A. Anterior view showing a major shear-compression fracture with comminution. B. right lateral view, and C. posterior view showing the intact fused epiphysis.
FIGURE 3. CMM-V-10108 in A Miocene cetacean vertebra showing a partially healed longitudinal shear-compression fracture, possibly the result of domoic acid toxicity or failed predation
FIGURE 3. CMM-V-10108, shear-fractured Miocene cetacean lumbar vertebra in three transverse CT-scan images. These CT-scan images cut through the vertebra in an anterodorsal-posteroventral direction. A. CT-scan image through the anterior portion of the vertebra showing the wide-open lumen of the shear-compression fracture. B. CT-scan image from approximately 1 cm behind A, showing the thickness of the periosteal reactive bone layer. C. CT-image at about the midpoint in the length of the vertebra showing the posterior-most part of the sheared base of the centrum compressed (telescoped) into the body of the centrum.
FIGURE 7. CMM-V-8522 in A Miocene cetacean vertebra showing a partially healed longitudinal shear-compression fracture, possibly the result of domoic acid toxicity or failed predation
FIGURE 7. CMM-V-8522, Otodus megalodon lower anterior tooth in labial view. This tooth was found touching one of the two pathological vertebrae (CMM-V-10108). Notice the spall-fracture marking the tip of the tooth. White scale bar equals 10 mm.
FIGURE 6. CMM-V-10108, a in A Miocene cetacean vertebra showing a partially healed longitudinal shear-compression fracture, possibly the result of domoic acid toxicity or failed predation
FIGURE 6. CMM-V-10108, a second Miocene pathological cetacean vertebra (also shown in Figure 5) associated with the one shown in Figures 2-4. A. CT-scan image towards the anterior end of the vertebra. B. CT-scan image at about the midpoint in the length of the vertebra showing the thickness of the periosteal reactive bone.
FIGURE 8 in A Miocene cetacean vertebra showing a partially healed longitudinal shear-compression fracture, possibly the result of domoic acid toxicity or failed predation
FIGURE 8. One possible way in which the shear-compression fracture occurred in CMM-V-10108. The posterior vertebral column was severely hyperflexed to such a degree that at least one of its vertebrae experienced a shear-compression fracture, and the periosteum was pulled away from most of the sides of both vertebrae. Artwork by Clarence (Shoe) Schumaker (CMM).
FIGURE 5. CMM-V-10108, a in A Miocene cetacean vertebra showing a partially healed longitudinal shear-compression fracture, possibly the result of domoic acid toxicity or failed predation
FIGURE 5. CMM-V-10108, a second Miocene pathological cetacean vertebra (CT-scans shown in Figure 6) associated with the one shown in Figures 2-4. A. Posterior view showing that the neural spine is incomplete and that the sides of the centrum are covered with periosteal reactive bone. B. ventral view to highlight the periosteal reactive bone. In B, the anterior end of the centrum is up.
FIGURE. 1 in A Miocene cetacean vertebra showing a partially healed longitudinal shear-compression fracture, possibly the result of domoic acid toxicity or failed predation
FIGURE. 1. The site along Calvert Cliffs where the two pathological cetacean vertebrae (CMM-V-10108) and associated Otodus megalodon tooth (CMM-V-8522) were found in situ in Shattuck-Zone 12. Looking north along the cliffs at Warrior's Rest. Photo by M. Ellwood.
FIGURE 4. CMM-V-10108, a in A Miocene cetacean vertebra showing a partially healed longitudinal shear-compression fracture, possibly the result of domoic acid toxicity or failed predation
FIGURE 4. CMM-V-10108, a single CT-scan image in the sagittal plane of a Miocene pathological cetacean vertebra in left lateral view showing the broken lower portion of the centrum, the displaced piece of bone, and the new bone growth (periosteal reactive bone ventrally).
Evaluation of the shucking of certain species of scallops contaminated with domoic acid with a view to the production of edible parts meeting the safety requirements foreseen in the Union legislation - Summary statistics on occurrence and consumption data and exposure assessment results
<p>DomoicAcid_Raw_Occurrence_Data.CSV contains the raw occurrence dataset on Domoic Acid contaminant in scallops as extracted from EFSA DWH on the 9 June 2020, 16,369 samples presented in the opinion as described in its section 1.3.2. Occurrence data submitted to EFSA. The data is provided in .csv format. This dataset is compliant with EFSA SSD model and contains two additional columns documenting issues identified in the cleaning process (column: issue) and the action taken (column: outcome) to address the issue (e.g. delete record or update values in specific fields).</p> <p>The link to the catalogues of controlled terminologies can be found under "Related identifiers”.</p> <p><strong>Annex_</strong> DomoicAcid</p> <p>Table of contents</p> <p><br> Table A1</p> <p>Description of FoodEx2 codes used to describe scallop species and their anatomical parts</p> <p>Table A2</p> <p>Data cleaning steps applied to occurrence data on domoic acid in scallops</p> <p>Table A3</p> <p>Percentage of Left-Censored data and descriptive statistics for Limits of detection (LODs) and Limits of quantification (LOQs) for domoic acid in scallops (mg/kg)</p> <p>Table A4</p> <p>Descriptive statistics for domoic acid in scallops (mg/kg) as reported in the cleaned database (statistics weighted by number of units per sample)</p> <p>Table A5</p> <p>Descriptive statistics of body tissue weights (g) of scallops as submitted by data providers</p>
California Sea Lion Stranding Records from Quantifying the linkages between California sea lion (Zalophus californianus) strandings and particulate domoic acid concentrations at piers across Southern California
<p>Pacific Marine Mammal Center (PMMC) is a member of the West Coast Marine Mammal Stranding Network, which was established under the United States Marine Mammal Protection Act by the National Oceanic and Atmospheric Administration (NOAA) to respond to stranded marine mammals. PMMC rescues, rehabilitates, and releases sick and injured marine mammals along the Orange County coastline, which is approximately 68 km of the Southern California coastline (<strong>Figure 1</strong>). All marine mammal rescue and rehabilitation activities are conducted by PMMC under a Stranding Agreement with National Marine Fisheries Service/NOAA.</p> <p>Patient case records from 2015-2019 for California sea lions (hereafter, sea lions) were reviewed and collated for each animal’s case presentation including sex, age class, seizure activity, postictal signs, comatose, abortion, and whether the sea lion was diagnosed by the attending veterinarian with domoic acid intoxication following the behavioral diagnostic criteria outlined by Gulland et al., <a href="https://www.zotero.org/google-docs/?XUrLiy">(2002)</a>. Multiple veterinarians made diagnoses during the time series based on these criteria which may have introduced some variation in the diagnosis of domoic acid intoxication during the study period. Age classes were defined following Greig et al. <a href="https://www.zotero.org/google-docs/?DGqEGG">(2005)</a> using dentition, straight length, pregnancy status, and sexual dimorphism to classify a sea lion’s age class. The following demographic categories are included in this study: juvenile/subadult male, subadult female, adult male, and adult female. Younger sea lions in the pup and yearling age classes were excluded as sea lions within these age classes are generally the most common patients at the center and often strand due to malnutrition <a href="https://www.zotero.org/google-docs/?eTzjbp">(Bejarano et al., 2008a)</a>, and rarely present with acute or chronic domoic acid intoxication during blooms. Adult and subadult age classes are the most commonly affected by domoic acid intoxication <a href="https://www.zotero.org/google-docs/?6xP9cn">(Bejarano et al., 2008a)</a>. Only live sea lions that were rescued on the Orange County coastline, brought to PMMC's facility, and assessed by the attending veterinarian were included. Adult and subadult sea lions that died on the beach were excluded from the study cohort because an attending veterinarian could not assess clinical signs to diagnosis domoic acid intoxication prior to death.</p>
White Matter Tractography and Neurohistopathology after Chronic, Low-Level Exposure to Domoic Acid in a Nonhuman Primate Model
GEO Series GSE163026. Macaca fascicularis. 23 samples. Type: Expression profiling by high throughput sequencing.
Domoic acid disruption of neurodevelopment and behavior involves altered myelination in the spinal cord
GEO Series GSE140045. Danio rerio. 12 samples. Type: Expression profiling by high throughput sequencing.
Symptomatic Domoic Acid exposure in zebrafish
GEO Series GSE152814. Danio rerio. 17 samples. Type: Expression profiling by array.
Gene expression profiles in zebrafish brain after acute exposure to domoic acid at symptomatic and asymptomatic doses
GEO Series GSE12140. Danio rerio. 9 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.