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107 results for “Dorsal root ganglion”
Super-resolution analysis of the origins of the elementary events of ER calcium release in dorsal root ganglion neurons
<p>This is the data supplement for the paper entitled, "Super-resolution analysis of the origins of the elementary events of ER calcium release in dorsal root ganglion neurons"<br><br>There are two principal subdirectories within the enclosed zip file:</p><ol><li>10xEExM_data: The directory contains two exemplar datasets each of 10x Enhanced expansion microscopy images of IP3R1 and RyR immunolabelling in DRG soma, at the sub-plasmalemmal regions.<br> </li><li>Correlative Analysis: The directory contains two sub-directories of worked examples of data and correlative analysis of calcium sparks and dSTORM images of RyR and IP3R. The instructions for the code, run in IDL, are included in the Readme.txt enclosed within.</li></ol>
Data from: Kir2.1 modulation in macrophages sensitises dorsal root ganglion neurons through TNF secretion after nerve injury
<p>This data pertain to the manuscript titled "Kir2.1 modulation in macrophages sensitises dorsal root ganglion neurons through TNF secretion after nerve injury", currently in preprint on BioRxiv (https://doi.org/10.1101/2023.06.21.545843). The name of the data files correspond to the for each figure in the study. The data file in .csv format are organized so that they can easily be opened in R or other analysis language. To understand them and how they are labelled, it is advised to open the figure next to them and find the appropriate panel.</p> <p>Here are included:</p> <ul> <li>Example images of section of mouse dorsal root ganglion (DRG) after spared nerve injury (SNI), labelled for CX3CR1+ cells, Ki67 and MHC class II by immunohistochemistry.</li> <li>LC-MS-MS proteomic data set of CX3CR1+ cells from DRG of mice after SNI.</li> <li>Voltage clamp data of CX3CR1+ cells from DRG of mice after SNI</li> <li>Electrophysiological data sets (multi-electrode array, current clamp and voltage clamp) of dissociated DRG neurons treated with medium conditioned by CX3CR1+ or GFAP+ cells sorted from ipsilateral or contralateral DRG from mice after SNI. In addition, pharmacological treatments were added to the conditioned medium (CM).</li> </ul>
Data supporting "Changes in human dorsal root ganglion neuron excitability from modulating Nav 1.8 conductance are non-linear and depend on the conductances of the delayed rectifier and M-type potassium currents: a simulation study"
<p>Data and code supporting the article "Changes in human dorsal root ganglion neuron excitability from modulating Nav 1.8 conductance are non-linear and depend on the conductances of the delayed rectifier and M-type potassium currents: a simulation study".</p> <p> </p>
Data from: Characterisation of GFAP-Expressing Glial Cells in the Dorsal Root Ganglion after Spared Nerve Injury
<p>This data pertain to the paper titled "Characterisation of GFAP-Expressing Glial Cells in the Dorsal Root Ganglion after Spared Nerve Injury " by Elena A. Konnova, Alexandru-Florian Deftu, Paul Chu Sin Chung, Marie Pertin, Guylène Kirschmann, Isabelle Decosterd and Marc R. Suter. The name of the data files correspond to the for each figure in the study. The data file in .csv format are organized so that they can easily be opened in R or other analysis language. To understand them and how they are labelled, it is advised to open the figure next to them and find the appropriate panel.</p><p>Here are included:</p><ul><li>the representative images of immunohistochemistry for GFAP, IBA1, Ki67, NeuN, ATF3, FABP7, GS, Cx43, Kir4.1, MBP, L1CAM in the dorsal root ganglia (DRG) of hGFAP-CFP mice after spared nerve injury (SNI).</li><li>the western blot images of DRG samples and FACS sorted CFP+ cells from the DRG of hGFAP-CFP mice after SNI</li><li>the voltage clamp data of GFAP+ cells from DRG of hGFAP-CFP mice after SNI</li></ul><p> </p>
Data from: Unbiased analysis of cellular plasticity in the dorsal root ganglion after peripheral nerve injury
<p>Sectional images of rat dorsal root ganglia (DRG) 7 or 14 days after SNI or sham injury.</p> <p>Sections were immunostained for neurofilament (NF), glial fibrillary acidic protein (GFAP), and glutamine synthetase (GS) and imaged using large-field (tile) microscopy. Images were segmented with a deep learning method (deepflash2).</p> <p>Provided are: </p> <p>- 2-13 images per DRG from L4 or L5, ipsilateral (IL) or contralateral (CL) </p> <p>- corresponding segmentation masks for NF, GS, and GFAP </p> <p>- deep learning models for oval-shaped NF-positive structures and ring-like GS/GFAP-positive structures </p> <p>- annotated data that the deep learning models were trained on</p>
A Safety and Effectiveness Trial of Spinal Cord Stimulation of the Dorsal Root Ganglion for Chronic Lower Limb Pain
ClinicalTrials.gov study NCT01923285. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Genetic editing of primary human dorsal root ganglion neurons using CRISPR-Cas9
Open the record for dataset details and reuse information.
Dorsal Root Ganglion Stimulation for the Management of Painful Intractable Small Fibre Neuropathy:
ClinicalTrials.gov study NCT02435004. IPD Sharing: Not stated. Countries: 1. Publications: 1.
High-Voltage Pulsed Radiofrequency of the Lumbar Dorsal Root Ganglion for the Treatment of Chronic Lumbar Radicular and Neuropathic Pain; A Prospective, Doble-blinded and Randomized Controlled Trial
ClinicalTrials.gov study NCT06264297. IPD Sharing: UNDECIDED. Countries: 1. Publications: 12.
Intermittent vs. Continuous Dorsal Root Ganglion Stimulation
ClinicalTrials.gov study NCT04727216. IPD Sharing: NO. Countries: 1. Publications: 10.
Intermittent Dosing of Dorsal Root Ganglion Stimulation as an Alternate Paradigm to Continuous Low-Frequency Therapy
ClinicalTrials.gov study NCT04909138. IPD Sharing: NO. Countries: 1. Publications: 11.
Physiological Parameters in CRPS Patients Treated With Dorsal Root Ganglion Stimulation
ClinicalTrials.gov study NCT07147140. IPD Sharing: YES. Countries: 1. Publications: 1.
Magnetic Resonance Neurography Analysis of Healthy Human Thoracic Dorsal Root Ganglion
ClinicalTrials.gov study NCT06177379. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
Dorsal Root Ganglion Stimulation for the Treatment of Arthritic Knee Pain
ClinicalTrials.gov study NCT05103527. IPD Sharing: NO. Countries: 1. Publications: 6.
Low Level Laser Therapy in the Dorsal Root Ganglion in the Treatment of Chronic Low Back Pain
ClinicalTrials.gov study NCT02529670. IPD Sharing: Not stated. Countries: 1. Publications: 10.
A Post Market Study to Assess the Spinal Modulation Dorsal Root Ganglion Stimulator System in Chronic Post Surgical Pain
ClinicalTrials.gov study NCT02335229. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Comparison of Dorsal Column Stimulation to Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome
ClinicalTrials.gov study NCT03794024. IPD Sharing: NO. Countries: 1. Publications: 0.
Dorsal Root Ganglion Thermal Radiofrequency Versus Pulsed Radiofrequency for Metastatic Pain in Thoracic Vertebral Body
ClinicalTrials.gov study NCT03204942. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
A Post Market Study on Dorsal Root Ganglion (DRG) Stimulation in Failed Back Surgery Syndrome (FBSS)
ClinicalTrials.gov study NCT02335216. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effect of Sensory Stimulation Threshold on the Efficacy of Pulsed Radiofrequency Applied to the Dorsal Root Ganglion in Patients with Chronic Lumbar Radicular Pain
ClinicalTrials.gov study NCT06756893. IPD Sharing: YES. Countries: 0. Publications: 2.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.