Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
7
datasets available to search
ShareScore release 0.9.0
Dataset results
7 results for “Drug degradation”
Forced degradation of five drug substances for meRgeION validation
<p>Drug substance is subjected to acid hydrolysis and oxidative stress against a baseline condition. The goal here is to profile and identify various degradation products of five APIs by setting stress conditions more severe than recommended storage, in order to further understand the underlying chemical mechanisms</p> <p>Non-targeted profiling in DDA mode was conducted for samples at Day 0 (1 sample) and Day 7 (3 samples for 3 conditions) on Orbitrap Fusion Lumos. Converted data files were submitted to MZMine for feature detection. Folder change of each feature under different conditions was calculated in excel. We then built a LC-MS/MS data processing pipeline in meRgeION that enables degradation product annotation by searching the spectral database <em>Drug+</em> (lib_drug_plus_matrix.RData) and mechanism understanding through FBMN. </p> <p> </p>
Activating 2D MoS2 by loading 2D Cu-S nanoplatelets for improved visible light photocatalytic hydrogen evolution, drug degradation, and CO2 reduction
<p>Please see ref:</p> <p> </p> <p>Temerov, F.; Greco, R.; Celis, J.; Eslava, S.; Wang, W.; Yamamoto, T.; Cao, W. <em>Results Mater.</em> <strong>2024</strong>, 22, 100569</p>
The global anaerobic metabolism regulator fnr is necessary for the degradation of food dyes and drugs by Escherichia coli
GEO Series GSE235465. Escherichia coli. 23 samples. Type: Expression profiling by high throughput sequencing.
Quantification of Drugs and Their Degradation Products
ClinicalTrials.gov study NCT01828372. IPD Sharing: Not stated. Countries: 1. Publications: 0.
TMC435-TiDP16-C107: This Study Measures the (Possible) Influence of TMC435 on the Activity of a Selected Set of Drug-degrading Proteins by Measuring the Blood Levels of Drugs That Have Been Taken Toge
ClinicalTrials.gov study NCT00866853. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Xiangtong TM Full Degradation Sinus Drug Stent System Prospective, Open, Single-center, Randomized Controlled Clinical Trial
ClinicalTrials.gov study NCT06669130. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation
GEO Series GSE139016. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.