Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
8
datasets available to search
ShareScore release 0.9.0
Dataset results
8 results for “Duodenal cancer”
Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer
ClinicalTrials.gov study NCT02961374. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Incidence of Duodenal Stump Fistula After Gastrectomy for Gastric Cancer. A Randomized Controlled Trial
ClinicalTrials.gov study NCT03277144. IPD Sharing: NO. Countries: 1. Publications: 20.
Duodenal Cancer - Retrospective Analysis
ClinicalTrials.gov study NCT01661049. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Early Diagnosis of Pancreatic Cancer Duodenal Fluid-Based Biomarker Exploratory Study
ClinicalTrials.gov study NCT07030348. IPD Sharing: NO. Countries: 2. Publications: 0.
Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction
ClinicalTrials.gov study NCT00004910. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Sensitivity and Specificity of NGS in Detecting bMSI in Patients With Gastric, Duodenal and Small Intestinal Cancer
ClinicalTrials.gov study NCT03915171. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Gemcitabine Hydrochloride, Oxaliplatin, and Erlotinib Hydrochloride in Treating Patients With Advanced Biliary Tract Cancer, Pancreatic Cancer, Duodenal Cancer, or Ampullary Cancer
ClinicalTrials.gov study NCT00987766. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Dataset related to article "Immune infiltrating cells in duodenal cancers"
<p>This record contains data related to article "Immune infiltrating cells in duodenal cancers"</p> <p> </p> <p>Abstract.</p> <p> Background: Duodenal adenocarcinoma (DA) is a rare yet aggressive malignancy, with increasing incidence in the</p> <p>last decades. Its low frequency has hampered a thorough understanding of the pathogenesis of the disease and of</p> <p>its biology, limiting the identification of tailored therapeutic options. A large body of evidence has clearly shown the</p> <p>clinical relevance of immune cells in solid tumors, correlating immune features with post-surgical prognosis. The aim</p> <p>of this study was to analyze the immune contexture in a cohort of duodenal adenocarcinomas surgically resected at</p> <p>our Institution and define its correlation with clinical variables.</p> <p> Methods: Tissue slides from paraffin-embedded tumor specimens of 15 consecutive DA and 3 adenomas that</p> <p>underwent a pancreaticoduodenectomy in our center between 2010 to 2018 were immunohistochemically stained.</p> <p>The density (percentage of immune reactive area, IRA%) of immune markers CD45RO, CD8, CD20, IL-17, PD-1, CD68</p> <p>was quantified by computer-assisted image analysis. Demographic, clinical, histopathological data were collected.</p> <p> Results: In our population, median IRA % (IQR) of immune subsets was respectively CD45RO-TILs 2.19 (2.14), CD8-TIL</p> <p>0.42 (0.81), CD20-TILs 0.22 (0.51), CD20-TLT 2.84 (4.64), CD68-TAM 2.19 (1.56), IL17+</p> <p>cells 0.39 (0.39), PD1-TILs 0.19 (0.41).</p> <p>The median follow-up was 47.5 (22.4–63.3) months. At statistical analysis, the density of CD8-TILs inversely correlated</p> <p>with lymph node ratio (p = 0.013), number of metastatic lymph nodes (p = 0.019), and was lower in N+ adenocarcinomas</p> <p>compared to N0 (1.07 vs 0.29; p = 0.093), albeit not significantly. Stratifying patients for the N status, the density of</p> <p>CD8-TILs decreased with the increasing of the N stage (p = 0.065) and was lower in patients who experienced recurrence</p> <p>and died for the disease (0.276 vs 0.641; p = 0.044). Notably, also CD68-TAM distribution was different in patients</p> <p>who had recurrence versus patients who did not (1.028 vs 2.276; p = 0.036).</p> <p> Conclusions: Immune cells showed variable expression in correlation with common prognostic factors, suggesting</p> <p>T cell infiltration may play a protective role towards lymphatic spread of disease and nodal metastatization. Furthermore,</p> <p>T cell density and macrophage infiltration were associated to a lower risk of recurrence and disease related</p> <p>death. A multicentric approach may be indicated to allow analysis of larger cohorts of patients, potentially increasing</p> <p>the power of our observations.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.