Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
39
datasets available to search
ShareScore release 0.9.0
Dataset results
39 results for “Ecdysone”
Data from: Nutritional control of body size through FoxO-Ultraspiracle mediated ecdysone biosynthesis
Despite their fundamental importance for body size regulation, the mechanisms that stop growth are poorly understood. In Drosophila melanogaster, growth ceases in response to a peak of the molting hormone ecdysone that coincides with a nutrition-dependent checkpoint, critical weight. Previous studies indicate that insulin/insulin-like growth factor signaling (IIS)/Target of Rapamycin (TOR) signaling in the prothoracic glands (PGs) regulates ecdysone biosynthesis and critical weight. Here we elucidate a mechanism through which this occurs. We show that Forkhead Box class O (FoxO), a negative regulator of IIS/TOR, directly interacts with Ultraspiracle (Usp), part of the ecdysone receptor. While overexpressing FoxO in the PGs delays ecdysone biosynthesis and critical weight, disrupting FoxO–Usp binding reduces these delays. Further, feeding ecdysone to larvae eliminates the effects of critical weight. Thus, nutrition controls ecdysone biosynthesis partially via FoxO–Usp prior to critical weight, ensuring that growth only stops once larvae have achieved a target nutritional status.
Data from: Nutritional control of body size through FoxO-Ultraspiracle mediated ecdysone biosynthesis
Open the record for dataset details and reuse information.
Data from: Intra-organ growth coordination in Drosophila is mediated by systemic ecdysone signaling
Open the record for dataset details and reuse information.
Data from: Stage-specific plasticity in ovary size is regulated by insulin/insulin-like growth factor and ecdysone signalling in Drosophila
Open the record for dataset details and reuse information.
Drosophila E93 promotes adult development and suppresses larval responses to ecdysone during metamorphosis
GEO Series GSE181948. Drosophila melanogaster. 12 samples. Type: Expression profiling by high throughput sequencing.
Kc cells from Drosophila melanogaster during ecdysone treatment and CP190 knockdown
GEO Series GSE30741. Drosophila melanogaster. 26 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing.
ecdysone treated KC167 cells during Heat Shock and at Room Temperature
GEO Series GSE23824. Drosophila melanogaster. 9 samples. Type: Expression profiling by array.
Gene expression in Drosophila hemocytes at the onset of metamorphosis, and dependence to the Ecdysone Receptor
GEO Series GSE49326. Drosophila melanogaster. 12 samples. Type: Expression profiling by array.
Distribution of Drosophila insulator proteins after ecdysone treatment in Kc cells
GEO Series GSE30740. Drosophila melanogaster. 14 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Small RNA-seq during the ecdysone and heat-shock response in Drosophila Kc167 cells
GEO Series GSE69934. Drosophila melanogaster. 16 samples. Type: Non-coding RNA profiling by high throughput sequencing.
The negative elongation factor NELF promotes active transcription of Drosophila ecdysone-dependent genes
GEO Series GSE156847. Drosophila melanogaster. 53 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila
GEO Series GSE124254. Drosophila melanogaster. 12 samples. Type: Expression profiling by high throughput sequencing; Other.
Ecdysone signaling induces two phases of cell cycle exit in Drosophila cells
GEO Series GSE77562. Drosophila melanogaster. 12 samples. Type: Expression profiling by high throughput sequencing.
Ecdysone and Mediator trigger a metabolic switch uncoupling cell cycle from cell growth to end proliferation in Drosophila neural stem cells
GEO Series GSE53265. Drosophila melanogaster. 10 samples. Type: Expression profiling by high throughput sequencing.
Effect of loss of Ecdysone-induced protein 93F (E93) on the Drosophila melanogaster antennal transcriptome.
GEO Series GSE150296. Drosophila melanogaster. 6 samples. Type: Expression profiling by high throughput sequencing.
Drosophila transcription factors, Séance, Ouija board and Molting defective, cooperatively control ecdysone biosynthesis
GEO Series GSE104340. Drosophila melanogaster. 4 samples. Type: Expression profiling by high throughput sequencing.
Ecdysone signaling and transcript signature in Drosophila cells resistant against methoxyfenozide
GEO Series GSE17748. Drosophila melanogaster. 8 samples. Type: Expression profiling by array.
A direct role for cohesin in genome-wide gene regulation and Ecdysone-response in Drosophila salivary gland
GEO Series GSE21874. Drosophila melanogaster. 1 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Ecdysone Response Timecourse in Kc Cells
GEO Series GSE11625. Drosophila melanogaster. 32 samples. Type: Expression profiling by array.
Ecdysone-induced 3D chromatin reorganization involves active enhancers bound by Pipsqueak and Polycomb
GEO Series GSE118047. Drosophila melanogaster. 20 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.