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15
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ShareScore release 0.9.0
Dataset results
15 results for “Endoplasmic Reticulum (ER”
Data from: A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress
<p>Eukaryotes have evolved various quality control mechanisms to promote proteostasis in the ER. Selective removal of certain ER domains via autophagy (termed as ER-phagy) has emerged as a major quality control mechanism. However, the degree to which ER-phagy is employed by other branches of ER-quality control remains largely elusive. Here, we identify a cytosolic protein, C53, that is specifically recruited to autophagosomes during ER-stress, in both plant and mammalian cells. C53 interacts with ATG8 via a distinct binding epitope, featuring a shuffled ATG8 interacting motif (sAIM). C53 senses proteotoxic stress in the ER lumen by forming a tripartite receptor complex with the ER-associated ufmylation ligase UFL1 and its membrane adaptor DDRGK1. The C53/UFL1/DDRGK1 receptor complex is activated by stalled ribosomes and induces the degradation of internal or passenger proteins in the ER. Consistently, the C53 receptor complex and ufmylation mutants are highly susceptible to ER stress. Thus, C53 forms an ancient quality control pathway that bridges selective autophagy with ribosome-associated quality control in the ER.</p>
Data from: A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress
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Lipoic acid induced endoplasmic reticulum stress-mediated apoptosis in rat hepatoma cells:identification of new ER stress aggravator (ERSA)
GEO Series GSE59164. Rattus norvegicus. 12 samples. Type: Expression profiling by array.
ChIP-seq analysis of changes in H3K27ac by endoplasmic reticulum stress (ERS) in mouse primary hepatocytes.
GEO Series GSE122613. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum (ER) stress response
GEO Series GSE7215. Homo sapiens; Mus musculus. 4 samples. Type: Expression profiling by array.
Endoplasmic Reticulum (ER) Chaperones Are Effector Genes Mediating Long-Term Memory Consolidation
GEO Series GSE167566. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome profiling of cytosol, endoplasmic reticulum (ER), and pellet fraction from the Xenopus laevis oocyte and mature egg
GEO Series GSE199254. Xenopus laevis. 18 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic analysis of endoplasmic reticulum stress (ERS) regulated genes in mouse primary hepatocytes.
GEO Series GSE122507. Mus musculus. 6 samples. Type: Expression profiling by array.
Transcriptomic analysis of endoplasmic reticulum stress (ERS) regulated genes in mouse gastrocnemius muscle
GEO Series GSE123082. Mus musculus. 18 samples. Type: Expression profiling by array.
Transcriptomic analysis of endoplasmic reticulum stress (ERS) regulated genes in the liver of NFIL3 KO mice.
GEO Series GSE122506. Mus musculus. 20 samples. Type: Expression profiling by array.
Analysis of the IRE1/XBP1 unfolded protein response (UPR) pathway in Schmid metaphyseal chondrodysplasia hypertrophic chondrocyte endoplasmic reticulum (ER) stress
GEO Series GSE72261. Mus musculus. 12 samples. Type: Expression profiling by array.
A novel bystander effect in tamoxifen treatment: PPIB derived from ER+ cells attenuates ER- cells via endoplasmic reticulum stress-induced apoptosis
GEO Series GSE247920. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Unfolded protein response (UPR) and endoplasmic reticulum (ER) stress in acromegaly
GEO Series GSE153755. Danio rerio. 33 samples. Type: Expression profiling by high throughput sequencing.
GENE EXPRESSION ANALYSIS IN TOMATO (Lycopersicon esculentum) UNDER ENDOPLASMIC RETICULUM (ER) STRESS
GEO Series GSE220689. Solanum lycopersicum. 8 samples. Type: Expression profiling by high throughput sequencing.
Endoplasmic reticulum (ER) stress and the unfolded protein response (UPR)
GEO Series GSE27349. Homo sapiens; Mus musculus. 28 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.