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64 results for “Enteric nervous system”
Regional cytoarchitecture of the adult and developing mouse enteric nervous system
<p>The organization and cellular composition of tissues are key determinants of their biological function. In the mammalian gastrointestinal (GI) tract, the enteric nervous system (ENS) intercalates between muscular and epithelial layers of the gut wall and can control GI function independent of central nervous system (CNS) input. As in the CNS, distinct regions of the GI tract are highly specialized and support diverse functions, yet the regional and spatial organization of the ENS remains poorly characterized.<a href="https://www-sciencedirect-com.stanford.idm.oclc.org/science/article/pii/S0960982222013070?via%3Dihub#bib2"><sup>2</sup></a> Cellular arrangements, circuit connectivity patterns, and diverse cell types are known to underpin ENS functional complexity and GI function, but enteric neurons are most typically described only as a uniform meshwork of interconnected ganglia. Here, we present a bird’s eye view of the mouse ENS, describing its previously underappreciated cytoarchitecture and regional variation. We visually and computationally demonstrate that enteric neurons are organized in circumferential neuronal stripes. This organization emerges gradually during the perinatal period, with neuronal stripe formation in the small intestine (SI) preceding that in the colon. The width of neuronal stripes varies throughout the length of the GI tract, and distinct neuronal subtypes differentially populate specific regions of the GI tract, with stark contrasts between SI and colon as well as within subregions of each. This characterization provides a blueprint for future understanding of region-specific GI function and identifying ENS structural correlates of diverse GI disorders.</p>
Enteric Nervous System in Parkinson's Disease
ClinicalTrials.gov study NCT00491062. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Gene expression profile at single cell level of the enteric nervous system (ENS) of 5 days post fertilization (dpf) zebrafish
GEO Series GSE225510. Danio rerio. 1 samples. Type: Expression profiling by high throughput sequencing.
scRNA-sequencing reveals new enteric nervous system roles for GDNF, NRTN, and TBX3
GEO Series GSE156905. Mus musculus; Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Enteric nervous system: timecourse analysis of longitudinal muscle and myenteric plexus (LMMP) in mice
GEO Series GSE213604. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Joint transcriptional disruption of Ret and Ednrb drives cell fate reversal in the Enteric Nervous System in Hirschsprung disease [bulkRNA-seq]
GEO Series GSE227574. Mus musculus. 54 samples. Type: Expression profiling by high throughput sequencing.
Comparative transcriptomics reveal highly conserved regional programs between porcine and human colonic enteric nervous system
GEO Series GSE197106. Homo sapiens; Sus scrofa. 54 samples. Type: Expression profiling by high throughput sequencing.
The epigenetic regulator BAP1 is required before birth for differentiation and maintenance of the postnatal enteric nervous system in mice.
GEO Series GSE242001. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Single nucleus tanscriptomic analysis of the mouse enteric nervous system
GEO Series GSE308383. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Joint transcriptional disruption of Ret and Ednrb drives cell fate reversal in the Enteric Nervous System in Hirschsprung disease [scRNA-Seq]
GEO Series GSE255963. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Sequencing Reveals miRNAs Enriched in the Developing Mouse Enteric Nervous System [miRNA]
GEO Series GSE250527. Mus musculus. 8 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Testing the Ret and Sema3d genetic interaction in mouse enteric nervous system development
GEO Series GSE89627. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Ret loss-of-function decreases neural crest progenitor proliferation and restricts developmental fate potential during enteric nervous system development
GEO Series GSE192676. Mus musculus. 1003 samples. Type: Expression profiling by high throughput sequencing.
Sequencing Reveals miRNAs Enriched in the Developing Mouse Enteric Nervous System [mRNA]
GEO Series GSE250526. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
A combinatorial panel for flow cytometry-based isolation of enteric nervous system cells from human intestine
GEO Series GSE224252. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Expression analysis of adult zebrafish enteric nervous system
GEO Series GSE145885. Danio rerio. 10 samples. Type: Expression profiling by high throughput sequencing.
Tachykinin signaling defines distinct populations of glia in the enteric nervous system [scRNA-seq]
GEO Series GSE275795. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia (Single-cell expression analysis of small intestine enteric nervous system developmental data)
GEO Series GSE237713. Mus musculus. 592 samples. Type: Expression profiling by high throughput sequencing.
Enteric glia express proteolipid protein 1 and are a transcriptionally unique population of glia in the mammalian nervous system
GEO Series GSE72560. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Improving Gastrointestinal Function In High-Risk Newborns By Stimulation Of The Enteric Nervous System
ClinicalTrials.gov study NCT06057415. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.