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56 results for “Epicardial adipose tissue”
Dataset related to the article "Epicardial Adipose Tissue-Derived IL-1β Triggers Postoperative Atrial Fibrillation"
<p>This record contains raw data related to the article "Epicardial Adipose Tissue-Derived IL-1β Triggers Postoperative Atrial Fibrillation"</p> <p><strong>Background and aims:</strong> Post-operative atrial fibrillation (POAF), defined as new-onset AF in the immediate period after surgery, is associated with poor adverse cardiovascular events and a higher risk of permanent AF. Mechanisms leading to POAF are not completely understood and epicardial adipose tissue (EAT) inflammation could be a potent trigger. Here, we aim at exploring the link between EAT-secreted interleukin (IL)-1β, atrial remodeling, and POAF in a population of coronary artery disease (CAD) patients. <strong>Methods:</strong> We collected EAT and atrial biopsies from 40 CAD patients undergoing cardiac surgery. Serum samples and EAT-conditioned media were screened for IL-1β and IL-1ra. Atrial fibrosis was evaluated at histology. The potential role of NLRP3 inflammasome activation in promoting fibrosis was explored <em>in vitro</em> by exposing human atrial fibroblasts to IL-1β and IL-18. <strong>Results:</strong> 40% of patients developed POAF. Patients with and without POAF were homogeneous for clinical and echocardiographic parameters, including left atrial volume and EAT thickness. POAF was not associated with atrial fibrosis at histology. No significant difference was observed in serum IL-1β and IL-1ra levels between POAF and no-POAF patients. EAT-mediated IL-1β secretion and expression were significantly higher in the POAF group compared to the no-POAF group. The <em>in vitro</em> study showed that both IL-1β and IL-18 increase fibroblasts' proliferation and collagen production. Moreover, the stimulated cells perpetuated inflammation and fibrosis by producing IL-1β and transforming growth factor (TGF)-β. <strong>Conclusion:</strong> EAT could exert a relevant role both in POAF occurrence and in atrial fibrotic remodeling.</p>
Correlation analysis of epicardial adipose tissue and ventricular myocardial strain in Chinese amateur marathoners using cardiac magnetic resonance
<p><span>The volume of epicardial adipose tissue (EAT) is associated with an increased incidence of cardiovascular disease (CVD); however, only a few studies have examined its effect on the myocardial function of endurance in athletes. The association between the EAT and the variation of myocardial function is still unclear in amateur marathoners. Consequently, by using some sedentary individuals as the control, this study aims to evaluate the correlation between the EAT volume and the myocardial strain in the left and right ventricles of Chinese amateur marathoners by cardiac magnetic resonance (CMR).</span>The volume of epicardial adipose tissue (EAT) is associated with an increased incidence of cardiovascular disease (CVD); however, only a few studies have examined its effect on the myocardial function of endurance in athletes. The association between the EAT and the variation of myocardial function is still unclear in amateur marathoners. Consequently, by using some sedentary individuals as the control, this study aims to evaluate the correlation between the EAT volume and the myocardial strain in the left and right ventricles of Chinese amateur marathoners by cardiac magnetic resonance (CMR).</p>
Epicardial Adipose Tissue Thickness and the Related Factors in Patients With Ankylosing Spondylitis
ClinicalTrials.gov study NCT06094686. IPD Sharing: NO. Countries: 1. Publications: 3.
The Benefits of the Measureof Epicardial Adipose Tissue During Coronary Calcium Assessment of the Refine Cardiovascular Risk Assessment at Reunion Island.
ClinicalTrials.gov study NCT07090629. IPD Sharing: NO. Countries: 1. Publications: 0.
Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction
ClinicalTrials.gov study NCT07178145. IPD Sharing: UNDECIDED. Countries: 1. Publications: 36.
Correlation Between NAFLD, Epicardial Adipose Tissue and Vascular Inflammation Measured by Positron Emission Tomography (PET) With 18F-fluoro-deoxyglucose (FDG)
ClinicalTrials.gov study NCT01958411. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Prediction of Coronary Artery Disease Severity by Epicardial Adipose Tissue Thickness
ClinicalTrials.gov study NCT03308539. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Influence of EPICardial Adipose Tissue in HEART Diseases: EPICHEART Study
ClinicalTrials.gov study NCT03280433. IPD Sharing: NO. Countries: 1. Publications: 1.
Epicardial Adipose Tissue Thickness PredIcts Obstructive Coronary Artery Disease in Acute Coronary Syndrome Patients
ClinicalTrials.gov study NCT03787797. IPD Sharing: YES. Countries: 1. Publications: 1.
Effect of Oral Semaglutide on Epicardial and Pericoronary Adipose Tissues in Type 2 Diabetes After Myocardial Infarction
ClinicalTrials.gov study NCT06557811. IPD Sharing: Not stated. Countries: 1. Publications: 22.
Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese Diabetics
ClinicalTrials.gov study NCT02042664. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Epicardial Adipose Tissue and Arterial Stiffness in People Living With Diabetes (METAB-CV-PWV)
ClinicalTrials.gov study NCT05681533. IPD Sharing: NO. Countries: 1. Publications: 1.
Impact of Bariatric Surgery on Epicardial Adipose Tissue and on Myocardial Function
ClinicalTrials.gov study NCT01284816. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Efficacy Study of Olmesartan Medoxomil on Coronary Atherosclerosis and Epicardial Adipose Tissue(EAT)
ClinicalTrials.gov study NCT02360956. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Correlation analysis of epicardial adipose tissue and ventricular myocardial strain in Chinese amateur marathoners using cardiac magnetic resonance
Open the record for dataset details and reuse information.
Dapagliflozin in Reducing Epicardial Adipose Tissue in Heart Failure with Preserved Ejection Fraction
ClinicalTrials.gov study NCT06510270. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
GE/miRNA expression profile of Human Epicardial Adipose Tissue (EAT) and Subcutaneous Adipose Tissue (SAT) in Patients with Coronary Artery Disease (CAD) vs. Controls (CTRL) - PART 2 - miRNA
GEO Series GSE64563. Homo sapiens. 46 samples. Type: Non-coding RNA profiling by array.
Transcriptome analysis of Epicardial Adipose Tissue from obese, diabetic and lean individulas
GEO Series GSE179455. Homo sapiens. 19 samples. Type: Expression profiling by high throughput sequencing.
A Western Dietary Pattern and Atorvastatin Induce Epicardial Adipose Tissue Interferon Signaling in the Ossabaw Pig
GEO Series GSE129301. Sus scrofa. 27 samples. Type: Expression profiling by high throughput sequencing.
CITE-Seq analysis of immune populations in paired human epicardial adipose tissue and right atrial appendage tissue samples
GEO Series GSE263154. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing; Other.
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