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431 results for “Family type”
Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor therapy reduces the level of DNA damage in patients with heterozygous familial hypercholesterolemia
<p><span><span>Heterozygous Familial Hypercholesterolaemia (HeFH) is a common autosomal dominant genetic disease (1:300) characterized by elevated LDL-C leading to premature atherosclerosis. Treatment with a PCSK9 inhibitor (iPCSK9) is recommended in high cardiovascular risk FH patients if the treatment goal is not achieved on maximal tolerated statin plus ezetimibe. </span></span><span>The aim of this study was to </span><span><span>examine the changes in DNA damage in HeFH patients associated with iPCSK9 use. </span></span><span>Fifty-seven patients were included: a normolipidemic group (control; n=20) and patients with HeFH (study group; n=36). DNA damage was determined by alkaline comet assay. PCSK9 protein level was assessed by ELISA. </span><span>The levels of Lp(a) in human serum were quantitatively turbidimetrically assay.</span><span> </span><span>PCSK9i treatment was associated with lower DNA damage, Lp(a), PCSK9 and lipid profile than before treatment. However, 20 of 36 patients still had Lp(a) values above 125 nmol/L, and reduced Lp(a) did not correlate with reduced DNA damage. Reduced PCSK9 moderately (r=0.48) correlates with reduced DNA damage</span><span><span>. PCSK9i therapy reduces the level of DNA damage in HeFH patients, regardless of the type of inhibitor. The reduction in DNA damage is not related to the changes in lipid profile or Lp(a) induced by PCSK9i, but it is dependent on PCSK9 level.</span></span></p>
Fig. 4. Types. A–B in All-inclusive descriptions of new freshwater snail taxa of the hyperdiverse family Tateidae (Gastropoda, Caenogastropoda) from the South Island of New Zealand
Fig. 4. Types. A–B. Catapyrgus jami sp. nov. C–D. Opacuincola lisannea sp. nov. (D from northern locality). E–F. Op. gretathunbergae sp. nov. G–H. Op. mete kahurangi subsp. nov. I–J. Obtusopyrgus farri sp. nov. A, C, E, G, I, holotypes, rest paratypes.
Gaia DR3 asteroid reflectance spectra: L-type families, memberships and ages
<p>The Gaia Data Release 3 (DR3) contains reflectance spectra at visible wavelengths for 60,518 asteroids over the range between 374-1034 nm, representing a large sample that is well suited to studies of asteroid families.</p> <p>We wanted to assess the potential of Gaia spectra in identifying asteroid family members. Here, we focus on two L-type families, namely Tirela/Klumpkea and Watsonia. These families are known for their connection to Barbarian asteroids, which are potentially abundant in calcium-aluminum rich inclusions (CAIs).</p> <p>The method we developed to establish family memberships is based (1) on a color taxonomy specifically built on Gaia data and (2) on the similarity of spectra of candidate members with the template spectrum of a specific family.</p> <p>Our work demonstrates the advantage of combining the classical hierarchical clustering method (HCM) approach to spectral properties obtained by Gaia for the study of asteroid families. Future data releases are expected to further expand the capabilities in this domain.</p> <p>The memberships for the Tirela/Klumpkea and Watsonia families are reported here. The columns report, from left to right: the identifier of the asteroid, the absolute magnitude, the proper elements (semi-major axis, eccentricity and sine of the inclination, taken from AFP, Novaković et al., 2022), NEOWISE albedo (Masiero et al., 2011) and spectral type from our color taxonomy. For the objects that are not directly classified into the S and L classes, their most probable spectral type is also reported. </p>
Family Type, Mental and Physical Health of in-school Female Adolescents in Ado-Ekiti, Nigeria
<p>This dataset is based on a cross-sectional survey conducted in Ado-Ekiti, Nigeria among in-school female adolescents. The general objective of the study was to examine the influence of family type on the physical and mental health of in-school female adolescents. The data were obtained in 2017 from in-school female adolescents aged 10-18 years old. The respondents were randomly selected from four purposively selected secondary schools. Two schools were selected from the government-owned public schools and two from schools owned by individuals or private organizations. Nigeria operates a six-year secondary education; three years at the junior secondary school (JSS 1-3) and three years at the senior secondary (SS 1-3). The population for this study excluded students in SS3 because they had just concluded their terminal examination at the time of this study. Using the formula proposed by (Krejcie & Morgan, 1970) for deriving a small sample when the population is known, a sample size of 383 was derived from a population of 1656 female students in the four schools. With 10% added to adjust for non-response, a total of 421 students were involved in the study. The number of respondents allocated to each school was proportional to the size of the female students' population in each school. In each school, respondents were assigned to classes proportional to the size, and the particular respondents were identified using a random number. Data were collected with a self-administered structured questionnaire which was piloted before the actual survey. The data is saved in Stata format. </p> <p>A scale for measuring self-reported mental well was designed using questions adapted from Ross, Mirowsky, & Goldsteen (1990) and (Langton & Berger, 2011). The scale reliability coefficient was 0.85. The students were asked to state how often they experience 22 conditions such as feeling sad, discouraged, lonely, hopeless, worthless, wishing you were dead, having trouble concentrating, having difficulty sleeping, crying, and worried among others. </p> <p>Physical health was measured using a scale generated with questions adapted from (Langton & Berger, 2011; Ross et al., 1990). The students were asked to state the frequency of experiencing seven conditions in the month before the survey: feeling sick, tired, dizzy, having chest pain, a headache, muscle or joint pain, and stomach ache. The response options were every day, more than two times, two times, once, and never, graded 1-5.</p> <p>Family type was categorised in four ways: 1) two-parent and single parent. Two parents comprised of couples who were legally married and those who were living together in a consensual union whereas single parents comprised never married, widowed, divorced, and separated mother or father. 2) two-parent (monogamous), two-parent (polygynous), and single parent 3) two-parent, single father, and single mother 4) two-parent, never married, widowed, divorced, and separated</p>
Рис. 7. Варианты преΑсказанной Αоменной структуры моΛекуΛ аΑгезии гемоцитов моΛΛюсков Planorbarius corneus. УсΛовные обозначения и сокращения: 1–3 — β-интегрины, 4–5 — α-интегрины, 6–7 — сеΛектины, 8–11 — моΛекуΛы семейства САМ (сell adhesiom molecues), INB — субъеΑиницы β-интегрина, IntegrinBcyt — цитопΛазматический Αомен β-интегрина, CY — цистатинопоΑобный Αомен, Int alpha — Αомен α-интегрина, FN3 — Αомен фибронектина типа 3, CCP — Αомен контроΛя компΛемента Fig. 7. Variants of the predicted domain structure of adhesion molecules from hemocytes of Planorbarius corneus molluscs. Symbols and abbreviations: 1–3 — β-integrins, 4–5 — α–integrins, 6–7 — selectins, 8–11 — molecules of the СAM family (cell adhesion molecules), INB — β-integrin subunits, IntegrinBcyt — cytoplasmic domain of β-integrin, CY — cystatin-like domain, Int alpha — α-integrin domain, FN3 — fibronectin type 3 domain, CCP — complement control protein domain in Pathogen recognition molecules from hemocytes of Planorbarius corneus molluscs (Planorbidae, Pulmonata)
Рис. 7. Варианты преΑсказанной Αоменной структуры моΛекуΛ аΑгезии гемоцитов моΛΛюсков Planorbarius corneus. УсΛовные обозначения и сокращения: 1–3 — β-интегрины, 4–5 — α-интегрины, 6–7 — сеΛектины, 8–11 — моΛекуΛы семейства САМ (сell adhesiom molecues), INB — субъеΑиницы β-интегрина, IntegrinBcyt — цитопΛазматический Αомен β-интегрина, CY — цистатинопоΑобный Αомен, Int alpha — Αомен α-интегрина, FN3 — Αомен фибронектина типа 3, CCP — Αомен контроΛя компΛемента Fig. 7. Variants of the predicted domain structure of adhesion molecules from hemocytes of Planorbarius corneus molluscs. Symbols and abbreviations: 1–3 — β-integrins, 4–5 — α–integrins, 6–7 — selectins, 8–11 — molecules of the СAM family (cell adhesion molecules), INB — β-integrin subunits, IntegrinBcyt — cytoplasmic domain of β-integrin, CY — cystatin-like domain, Int alpha — α-integrin domain, FN3 — fibronectin type 3 domain, CCP — complement control protein domain
Fig. 283. Cearachelys placidoi, MPSC uncatalogued type specimen. A, C in EVOLUTION OF THE SIDE-NECKED TURTLES: THE FAMILIES BOTHREMYDIDAE, EURAXEMYDIDAE, AND ARARIPEMYDIDAE
Fig. 283. Cearachelys placidoi, MPSC uncatalogued type specimen. A, C, quadrate and cavum tympani in lateral view; B, D, quadrate and cavum tympani in anterolateral view. Figures are of left side reversed. Gray indicates extent of antrum postoticum. [A.M. Phillips and E.S. Gaffney, del.]
Linked collectors and determiners for: The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution II. Family Halictidae, subfamilies Rophitinae, Nomiinae, and Nomioidinae.
Natural history specimen data linked to collectors and determiners held within, "The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution II. Family Halictidae, subfamilies Rophitinae, Nomiinae, and Nomioidinae". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/9314cc58-f79b-4a7e-b6d4-3955d0824401">https://bionomia.net/dataset/9314cc58-f79b-4a7e-b6d4-3955d0824401</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/9314cc58-f79b-4a7e-b6d4-3955d0824401">https://gbif.org/dataset/9314cc58-f79b-4a7e-b6d4-3955d0824401</a>. Formatted as a Frictionless Data package.
Linked collectors and determiners for: Revisiting the type of Cespitularia stolonifera Gohar, 1938 leads to the description of a new genus and a species of the family Xeniidae (Octocorallia, Alcyonacea).
Natural history specimen data linked to collectors and determiners held within, "Revisiting the type of Cespitularia stolonifera Gohar, 1938 leads to the description of a new genus and a species of the family Xeniidae (Octocorallia, Alcyonacea)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/6d7b4e8c-9086-45b7-87f2-eee086af0c5a">https://bionomia.net/dataset/6d7b4e8c-9086-45b7-87f2-eee086af0c5a</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/6d7b4e8c-9086-45b7-87f2-eee086af0c5a">https://gbif.org/dataset/6d7b4e8c-9086-45b7-87f2-eee086af0c5a</a>. Formatted as a Frictionless Data package.
Distribution. Endemic to S India (Kolar district, Karnataka), known only from type locality. Previously also on nearby Therahalli, where now absent. in Family Hipposideridae (Old World Leaf-nosed Bats)
Distribution. Endemic to S India (Kolar district, Karnataka), known only from type locality. Previously also on nearby Therahalli, where now absent.
FIGURES 34a–e in The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution III Family Halictidae, genera Halictus Latreille, 1804, and Sphecodes Latreille, 1804
FIGURES 34a–e. Sphecodes kozlovi Astafurova & Proshchalykin, 2015. Holotype, male: a—habitus, lateral view, and labels; b—metasoma, dorsal view; c—mesosoma, dorsal view; d—head, frontal view; e—genitalia, dorsal view.
FIGURES 15a–e. Halictus minor Morawitz, 1876 in The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution III Family Halictidae, genera Halictus Latreille, 1804, and Sphecodes Latreille, 1804
FIGURES 15a–e. Halictus minor Morawitz, 1876. Lectotype, female: a—habitus, lateral view; b—metasoma, dorsal view; c—head, frontal view; d—mesosoma dorsal view; e—labels.
FIGURES 26a–f. Halictus turanicus Morawitz, 1893 in The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution III Family Halictidae, genera Halictus Latreille, 1804, and Sphecodes Latreille, 1804
FIGURES 26a–f. Halictus turanicus Morawitz, 1893. Holotype, male: a—habitus, lateral view; b— metasoma, dorsal view; c—head, frontal view; d—mesosoma, dorsal view; e—genitalia; f—labels.
FIGURES 30a–e. Hylaeus senilis Eversmann, 1852 in The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution III Family Halictidae, genera Halictus Latreille, 1804, and Sphecodes Latreille, 1804
FIGURES 30a–e. Hylaeus senilis Eversmann, 1852. Lectotype, female: a—habitus, lateral view; b—metasoma, dorsal view; c—head, frontal view; d—mesosoma, dorsal view; e—labels.
FIGURES 13a–e. Halictus marikovskayae Pesenko, 1986 in The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution III Family Halictidae, genera Halictus Latreille, 1804, and Sphecodes Latreille, 1804
FIGURES 13a–e. Halictus marikovskayae Pesenko, 1986. Holotype, female: a—habitus, lateral view; b— metasoma, dorsal view; c—head, frontal view; d—mesosoma, dorsal view; e—labels.
FIGURES 22a–f. Halictus rudolphae Pesenko, 1984 in The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution III Family Halictidae, genera Halictus Latreille, 1804, and Sphecodes Latreille, 1804
FIGURES 22a–f. Halictus rudolphae Pesenko, 1984. Holotype, male: a—habitus, lateral view; b— metasoma, dorsal view; c—mesosoma, dorsal view; d—head, frontal view; e—labels; f—genitalia.
FIGURES 19a–e in The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution III Family Halictidae, genera Halictus Latreille, 1804, and Sphecodes Latreille, 1804
FIGURES 19a–e. Halictus petraeus Blüthgen, 1933. Holotype, female: a—habitus, lateral view; b— head, frontal view; cmesosoma, dorsal view; d—metasoma, dorsal view; e—labels.
FIGURES 6a–e. Halictus compressus transvolgensis Pesenko, 1985 in The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution III Family Halictidae, genera Halictus Latreille, 1804, and Sphecodes Latreille, 1804
FIGURES 6a–e. Halictus compressus transvolgensis Pesenko, 1985. Holotype, male: a—habitus, lateral view; b—head, frontal view; c—mesosoma, dorsal view; d—metasoma, dorsal view; e—labels.
FIGURES 4a–e. Halictus cephalicus Morawitz, 1874 in The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution III Family Halictidae, genera Halictus Latreille, 1804, and Sphecodes Latreille, 1804
FIGURES 4a–e. Halictus cephalicus Morawitz, 1874. Lectotype, female: a—habitus, lateral view; b—labels; c—mesosoma, dorsal view; d—head, frontal view; e—metasoma, dorsal view.
FIGURES 3a–e in The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution III Family Halictidae, genera Halictus Latreille, 1804, and Sphecodes Latreille, 1804
FIGURES 3a–e. Halictus bucharicus Blüthgen, 1936. Lectotype, female: a—habitus, lateral view; b—metasoma, dorsal view; c—head, frontal view; d—labels; e—mesosoma, dorsal view.
FIGURES 1a–f. Halictus atripes Morawitz, 1893 in The type specimens of bees (Hymenoptera, Apoidea) deposited in the Zoological Institute of the Russian Academy of Sciences, St. Petersburg. Contribution III Family Halictidae, genera Halictus Latreille, 1804, and Sphecodes Latreille, 1804
FIGURES 1a–f. Halictus atripes Morawitz, 1893. Holotype, male: a—habitus, lateral view; b—head, frontal view; c—mesosoma, dorsal view; d—genitalia, dorsal view; e—labels; f—metasoma, dorsal view.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
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OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.