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144 results for “Fibroblast Growth Factors”
Data from: Controlled release of basic fibroblast growth factor from a peptide biomaterial for bone regeneration
<p>Self-assembled peptide scaffolds based on D-RADA16 (D16) are an important matrix for controlled drug release and 3D cell culture. In this work, D16 peptide hydrogels were coated on artificial bone composed of nano-hydroxyapatite/polyamide 66 (NHA/PA66) to obtain a porous drug-releasing structure for treating bone defects. The developed materials were characterized via transmission electron microscopy (TEM), scanning electron microscopy (SEM). The proliferation and adhesion of bone mesenchymal stem cells (BMSCs) were examined by Confocal laser microscopy (CLS) and CCK-8 experiments. The osteogenic ability of the porous materials towards bone BMSCs was examined in vitro by staining with Alizarin Red S and alkaline phosphatase (ALP) and bioactivity were evaluated in vivo. The results revealed that NHA/PA66/D-RADA16/bFGF reduce the degradation rate of D16 hydrogels and prolong sustained release of bFGF, which would promote BMSCs proliferation, adhesion and osteogenesis in vitro and bone repair in vivo. Thus, it deserves more attention and is worthy of further research.</p>
Study of Dietary Additive Phosphorus on Proteinuria and Fibroblast Growth Factor-23
ClinicalTrials.gov study NCT02020785. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Dose Escalation Pan-FGFR (Fibroblast Growth Factor Receptor) Inhibitor (Rogaratinib)
ClinicalTrials.gov study NCT01976741. IPD Sharing: Not stated. Countries: 7. Publications: 2.
Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH)
ClinicalTrials.gov study NCT02163577. IPD Sharing: Not stated. Countries: 4. Publications: 3.
Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma
ClinicalTrials.gov study NCT03410693. IPD Sharing: Not stated. Countries: 29. Publications: 2.
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations
ClinicalTrials.gov study NCT03390504. IPD Sharing: Not stated. Countries: 27. Publications: 1.
Fibroblast Growth Factor-23 (FGF23) Reduction in Predialysis Chronic Kidney Disease (CKD)
ClinicalTrials.gov study NCT00843349. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Changes in Serum Fibroblast Growth Factor 21 (FGF21) Levels Correlated With Exercise
ClinicalTrials.gov study NCT01512368. IPD Sharing: Not stated. Countries: 1. Publications: 3.
The Effect of Lanthanum Carbonate on Fibroblast Growth Factor 23 ( FGF23) in Chronic Kidney Disease
ClinicalTrials.gov study NCT01002872. IPD Sharing: YES. Countries: 1. Publications: 6.
A Study of Erdafitinib in Participants With Advanced Solid Tumors and Fibroblast Growth Factor Receptor (FGFR) Gene Alterations
ClinicalTrials.gov study NCT04083976. IPD Sharing: YES. Countries: 15. Publications: 1.
Data from: Controlled release of basic fibroblast growth factor from a peptide biomaterial for bone regeneration
Open the record for dataset details and reuse information.
Fibroblast Growth Factor receptor signaling in cardiomyocytes is protective in the acute phase following ischemia-reperfusion injury
<p>Suplemental echocardiographic images</p>
Data from: A study on genetic variants of Fibroblast Growth Factor Receptor 2 (FGFR2) and the risk of breast cancer from North India
Genome-Wide Association Studies (GWAS) have identified Fibroblast growth factor receptor 2 (FGFR2) as a candidate gene for breast cancer with single nucleotide polymorphisms (SNPs) located in intron 2 region as the susceptibility loci strongly associated with the risk. However, replicate studies have often failed to extrapolate the association to diverse ethnic regions. This hints towards the existing heterogeneity among different populations, arising due to differential linkage disequilibrium (LD) structures and frequencies of SNPs within the associated regions of the genome. It is therefore important to revisit the previously linked candidates in varied population groups to unravel the extent of heterogeneity. In an attempt to investigate the role of FGFR2 polymorphisms in susceptibility to the risk of breast cancer among North Indian women, we genotyped rs2981582, rs1219648, rs2981578 and rs7895676 polymorphisms in 368 breast cancer patients and 484 healthy controls by Polymerase chain reaction-Restriction fragment length polymorphism (PCR-RFLP) assay. We observed a statistically significant association with breast cancer risk for all the four genetic variants (P<0.05). In per-allele model for rs2981582, rs1219648, rs7895676 and in dominant model for rs2981578, association remained significant after bonferroni correction (P<0.0125). On performing stratified analysis, significant correlations with various clinicopathological as well as environmental and lifestyle characteristics were observed. It was evident that rs1219648 and rs2981578 interacted with exogenous hormone use and advanced clinical stage III (after Bonferroni correction, P<0.000694), respectively. Furthermore, combined analysis on these four loci revealed that compared to women with 0–1 risk loci, those with 2–4 risk loci had increased risk (OR = 1.645, 95%CI = 1.152–2.347, P = 0.006). In haplotype analysis, for rs2981578, rs2981582 and rs1219648, risk haplotype (GTG) was associated with a significantly increased risk compared to the common (ACA) haplotype (OR = 1.365, 95% CI = 1.086–1.717, P = 0.008). Our results suggest that intron 2 SNPs of FGFR2 may contribute to genetic susceptibility of breast cancer in North India population.
Association of Vitamin D, Parathyroid Hormone and Fibroblast Growth Factor-23 With Infarction-related Arrhythmia in Patients With Acute Myocardial Infarction
ClinicalTrials.gov study NCT01971619. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Anemia Correction and Fibroblast Growth Factor 23 Levels in Chronic Kidney Disease , and Renal Transplant Patient
ClinicalTrials.gov study NCT03193073. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
The Effect and Safety of Recombinant Fibroblast Growth Factor-1 for Carpal Tunnel Syndrome
ClinicalTrials.gov study NCT06328166. IPD Sharing: YES. Countries: 1. Publications: 6.
Observing the Relationship of Fibroblast Growth Factor and Fibroblast in Thyroid Eye Disease
ClinicalTrials.gov study NCT03324022. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Fibroblast Growth Factor 23 and Sclerostin in Relation to Calcium in COVID-19 Patients
ClinicalTrials.gov study NCT05275491. IPD Sharing: Not stated. Countries: 1. Publications: 6.
A Study to Evaluate the Clinical Efficacy of JNJ-42756493 (Erdafitinib), A Pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, In Asian Participants With Advanced Non-Small-Cell Lu
ClinicalTrials.gov study NCT02699606. IPD Sharing: Not stated. Countries: 3. Publications: 1.
The Effect of Lanthanum Carbonate on Fibroblast Growth Factor 23
ClinicalTrials.gov study NCT01845090. IPD Sharing: Not stated. Countries: 1. Publications: 2.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.