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285 results for “Flavonoid”
Figure 1 in Phytochemical screening and evaluation of antioxidant, total phenolic and flavonoid contents in various weed plants associated with wheat crops
Figure 1. DPPH Assay for Convolvulus arvensis, Chenopodium murale, Avena fatua, Phalaris minor extracts in different solvents.
Figure 3. H 2O2 in Phytochemical screening and evaluation of antioxidant, total phenolic and flavonoid contents in various weed plants associated with wheat crops
Figure 3. H 2O2 Scavenging assay for Convolvulus arvensis, Chenopodium murale, Avena fatua, Phalaris minor extracts in different solvents.
Data described in the article "Nitrogen-Containing Flavonoids─Preparation and Biological Activity"
<p>The dataset includes supplementary data, i.e. the results of optimization of Ullmann reaction, cellular antioxidant and anti-inflammatory activity, cytotoxicity, antibacterial activity, and molecular docking, <sup>1</sup>H, <sup>13</sup>C{<sup>1</sup>H} NMR data, HPLC, and HRMS analyses of the study titled "Nitrogen-Containing Flavonoids─Preparation and Biological Activity" available here: <a href="https://doi.org/10.1021/acsomega.4c04627">https://doi.org/10.1021/acsomega.4c04627</a></p>
Navigating the Complex Solid Form Landscape of the Quercetin Flavonoid Molecule
<p>Data related to the paper published in Crystal Growth & Design, with doi:https://doi.org/10.1021/acs.cgd.3c00584.</p> <p>Quercetin, a naturally occurring bioflavonoid substance widely used in the nutraceutical and food industries, exists in various solid forms that can have different physicochemical properties, thus impacting this compound’s performance in various applications. In this work, we will clarify the complex solid-form landscape of this molecule. Two elusive isostructural solvates of quercetin were obtained from ethanol and methanol. The obtained crystals were characterized experimentally, but the crystallographic structure could not be solved due to their high instability. Nevertheless, the desolvated structure resulting from a high-temperature treatment (or prolonged storage at ambient conditions) of both these two labile crystals was characterized and solved via powder X-ray diffraction and solid-state nuclear magnetic resonance (SSNMR). This anhydrous crystal structure was compared with another anhydrous quercetin form obtained in our previous work, indicating that, at least, two different anhydrous polymorphs of quercetin exist. Navigating the solid-form landscape of quercetin is essential to ensure accurate control of the functional properties of food, nutraceutical, or pharmaceutical products containing crystal forms of this substance.</p>
Evaluation of bacterial bioinoculants and organic fertilizers on the growth of Furcraea sp. and the production of phenols and flavonoids
Furcraea sp. is a plant native to the Andean region that has a big impact in the economy due to the uses associates to the plant. This data set correspond to the results of the study "Effects of Bacterial Bioinoculants and Organic Fertilizers on Leaf Length, Total Phenol and Total Flavonoid Content in a Crop of Furcraea sp. in Sibundoy Putumayo". In the study, we applied bioinoculants and organic fertilizers either alone or in combination in order to determine their effect on the leaf lenght and the production of secondary metabolites. We present three data sets: the first one correspond to the leaf length (cm), that was measuere every 15 day during 400 days. This data was collected to determine how the different tratments applied affected the growth of the leaves of Furcraea sp. The second one is the total phenol content. It was measured by the Folin Ciocalteu method and the results were expressed as Equivalent mg of Galic acid/ g of dry vegetable material. The third one is the quantification of flavonoids, with the same thecnique mentioned before. The results were expressed as Equivalent mg of rutine/ g of dry vegetable materia. The aim of meassuring this two metabolites was to determine if there was any relationship between the products applied and their production.
Data from: Optimisation of biogenic synthesis of silver nanoparticles from flavonoid-rich Clinacanthus nutans leaf and stem aqueous extracts
<p>BACKGROUND: Silver nanoparticles (AgNPs) are widely used in food industries, biomedical, dentistry, catalysis, diagnostic biological probes, and sensors. The use of plant extract for AgNPs synthesis eliminates the process of maintaining cell culture and the process could be scaled up under a non-aseptic environment. The purpose of this study is to determine the classes of phytochemicals, to biosynthesise and characterise the AgNPs using Clinacanthus nutans leaf and stem extracts. In this study, AgNPs was synthesised from the aqueous extracts of C. nutans leaves and stems through a non-toxic, cost effective and eco-friendly method.</p> <p>RESULTS: The formation of AgNPs was confirmed by UV-Vis spectroscopy, and the size of AgNP-L (leaf) and AgNP-S (stem) were 114 and 129 nm, respectively. Transmission electron microscopy (TEM) analysis showed spherical nanoparticles with AgNP-L and AgNP-S ranging from 10-300 nm and 10-180 nm; with zeta potentials of AgNP-L and AgNP-S at -42.8 and -43.9 mV, respectively. XRD analysis matched the face-centred cubic structure of silver and was capped with bioactive compounds. FTIR analysis revealed the presence of few functional groups of phenolic and flavonoid compounds. These functional groups act as reducing agents in AgNPs synthesis.</p> <p>CONCLUSION: This result showed that the biogenically synthesised nanoparticles reduced silver ions to silver nanoparticles in aqueous condition and the AgNPs formed were stable and less toxic.</p>
A green extraction design for enhancing flavonoid compounds from the Ixora javanica flowers using a deep eutectic solvent
<p>In this study, an environmentally friendly extraction method for flavonoid compound from <em>Ixora javanica</em> as a new raw material candidate for herbal medicine and cosmetics, was developed. The objectives of the present work were to provide recommendations for the optimal extraction conditions and to investigate the effects of any extraction parameters on flavonoid yields from the <em>I. javanica</em> flower. The extraction process was performed using deep eutectic solvent (DES) (choline chloride and propylene glycol at molar ratio of 1:1) and ultrasound-assisted extraction (UAE) method. Both single-factor and response surface analyses using three-level and three-factor Box Behnken designs were conducted to obtain the optimum flavonoid concentrations. The results showed that the optimum extraction conditions for total flavonoids featured an extraction time of 40 min, 25% water content in DES, and a solid-to-liquid ratio of 1:25 g/mL. An extract obtained under optimum extraction conditions showed higher total flavonoid yields than an ethanolic extract which was used for comparison. Scanning electron microscope (SEM) images demonstrated that both of the solvents also showed different effects on the outer surface of the <em>I. javanica</em> flower during extraction process. In sum, our work succeeded in determining the optimum conditions for total flavonoids in the <em>I. javanica</em> flower using a green extraction method.</p>
Data for: Phytochemical shift from condensed tannins to flavonoids in transgenic Betula pendula decreases consumption and growth but improves growth efficiency of Epirrita autumnata larvae
<p>Despite active research, antiherbivore activity of specific plant phenolics remains largely unresolved. We constructed silver birch (<em>Betula pendula</em>) lines with modified phenolic metabolism to study the effects of foliar flavonoids and condensed tannins on consumption and growth of larvae of a generalist herbivore, the autumnal moth (<em>Epirrita autumnata</em>). We conducted a feeding experiment using birch lines in which expression of dihydroflavonol reductase (<em>DFR</em>), anthocyanidin synthase (<em>ANS</em>) or anthocyanidin reductase (<em>ANR</em>) had been decreased by RNA interference. Modification-specific effects on plant phenolics, nutrients and phenotype, and on larval consumption and growth were analyzed using uni- and multivariate methods. Inhibiting <em>DFR</em> expression increased the concentration of flavonoids at the expense of condensed tannins, and silencing <em>DFR </em>and <em>ANR </em>decreased leaf and plant size. <em>E. autumnata </em>larvae consumed on average 82% less of DFRi plants than of unmodified controls, suggesting that flavonoids or glandular trichomes deter larval feeding. However, larval growth efficiency was highest on low-tannin DFRi plants, indicating that condensed tannins (or their monomers) are physiologically more harmful than non-tannin flavonoids for <em>E. autumnata </em>larvae. Our results show that genetic manipulation of the flavonoid pathway in plants can effectively be used to produce altered phenolic profiles required for elucidating the roles of low-molecular weight phenolics and condensed tannins in plant–herbivore relationships, and suggest that phenolic secondary metabolites participate in regulation of plant growth.</p>
Characterization files for the analysis of Mg-Zn nanoferrites flavonoids
<p>Nanosized ferrites Mg<em><sub>x</sub></em>Zn<sub>1-<em>x</em></sub>Fe<sub>2</sub>O<sub>4</sub> (0 < <em>x </em><1) was effectively synthesized using a wet ferritization method. The obtained spinel nanoparticles were then treated with flavonoids (Flv) extracted from agricultural waste of <em>Punica granatum</em> L. and <em>Allium cepa </em>L. Various characterization techniques such as FTIR, XRD, DTA-TGA, VSM, FE-SEM, TEM, EDX, and BET were utilized to analyze the surface morphology, magnetic properties, and elemental composition. The X-ray diffractograms revealed that the synthesized Mg<em><sub>x</sub></em>Zn<sub>1-<em>x</em></sub>Fe<sub>2</sub>O<sub>4</sub> (MZFO) nanoparticles displayed a uniform cubic spinel structure, indicating the presence of a single phase. Morphological analysis revealed two distinct categories of MZFO nanoparticles: flower-shaped and plate-shaped particles. The attendance of Mg, Zn, O, Fe, and C elements in both MZFO and Flv/MZFO samples was confirmed by EDX analysis. TEM analysis further confirmed that each particle of the modified MZFO sample was a single crystal with an average particle size of 22 nm. Additionally, the modified MZFO nanoparticles exhibited a weight loss of 39.17% due to surface modification. Notably, the modified MZFO nanoparticles displayed remarkable superparamagnetic behavior with a saturation magnetization of up to 41.875 emu.g<sup>-1</sup>. BET analysis demonstrated that the Flv/MZFO nanoparticles possessed a mesoporous structure with a total pore volume of 0.1349 cm<sup>3</sup>/g, an average pore size of 17.044 nm, and a specific surface area of 31.655 m<sup>2</sup>/g. The conjugated Flv/MZFO nanoferrites exhibited significant antibacterial efficacy, with inhibition zones of 7 mm and 8 mm against Gram-positive and Gram-negative bacteria, respectively. </p>
Input parameters and output trajectory files for manuscript "Inhibitory Activity of Flavonoid Scaffolds on SARS-CoV-2 3CLPro: Insights from the Computational and Experimental Investigations"
<p>Input parameters used for molecular dynamics simulations on GROMACS 2022 software and the output trajectory files for calculating binding free energy, in the manuscript with the title: "Inhibitory Activity of Flavonoid Scaffolds on SARS-CoV-2 3CL<sup>Pro</sup>: Insights from the Computational and Experimental Investigations"</p>
Table of SwissADME Analysis of Flavonoid Compounds
<p>Tabulation of SwissADME Analysis for Journal Article: <em>In Silico Study</em> of Flavonoid Compound: Utilization of Molecular Simulation to Discover Drug Candidate for COVID-19</p>
Data associated with manuscript: "Foliar flavonoids across an elevation gradient: plasticity in response to UV, and links with floral pigmentation patterning"
<p>There are two datasets provided in this excel file. The data are flavonoid abundances of Argentina anserina [=Potentilla anserina] exposed to two levels of ultraviolet light in a greenhouse. The "leaf only data" tab has the combined foliar abundances of the major classes of flavonoids detected: chalcone, flavonone, flavone, flavonol, flavon-3-ol, and proanthocyanidin. This dataset was used to analyze the effect of UV treatment and elevation on flavonoid production in leaves. The "leaf and petal matching cmpnds" is the abundance of the major flavonoid classes in leaves and petals for only the compounds that were detected in both tissue types. This dataset was used for all analyses that related leaf flavonoids with petal flavonoids and petal UV pigmentation. </p>
Database review of studies on the impact of flavonoids released in nanoparticles on cytokine production.
<p>This table contains the data extracted from the source of evidence to analyze the role of flavonoids encapsulated in nanoparticles in the regulation of pro-inflammatory cytokines.</p>
Role of pollen flavonoids in the heather-bumble bee-parasite interactions
<p>Upload of scripts and datasets associated with the publication entitled: Role of pollen flavonoids in the heather-bumble bee-parasite interactions.</p>
Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell Disease
ClinicalTrials.gov study NCT04514510. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Carotenoid and Flavonoid Absorption From Red and Tangerine-Type Tomatoes
ClinicalTrials.gov study NCT01696773. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Characterization files for the analysis of Mg-Zn nanoferrites flavonoids
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Data for: Phytochemical shift from condensed tannins to flavonoids in transgenic Betula pendula decreases consumption and growth but improves growth efficiency of Epirrita autumnata larvae
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Data from: Optimisation of biogenic synthesis of silver nanoparticles from flavonoid-rich Clinacanthus nutans leaf and stem aqueous extracts
Open the record for dataset details and reuse information.
A green extraction design for enhancing flavonoid compounds from the Ixora javanica flowers using a deep eutectic solvent
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