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49 results for “Functional Senescence”
The timing of leaf senescence relates to flowering phenology and functional traits in 17 herbaceous species along elevational gradients
1. Leaf senescence is a major event in a plant's life history as autumn marks the end of the growing season. The optimal timing of leaf senescence is crucial to both, minimize risks of low temperature events and maximize carbon gain during the growing season. As abiotic conditions are currently changing at unprecedented rates, it is important to study how leaf senescence of different species is responding to these changes in order to forecast future growing season length and carbon sequestration potentials. In contrast to flowering phenology, data on autumn events is scarce and even more so for herbaceous than for woody plants, thus more information on this phenological stage is urgently needed. 2. We studied leaf senescence of 632 populations from 17 herbaceous species located along elevational gradients. We focussed on the beginning (5% of the population senesce, LS5) and peak (50% senesce, LS50) of leaf senescence. To see whether we can predict species-specific changes, we studied the link between LS5 and LS50 and flowering phenology as well as leaf functional traits related to plant performance. We looked at first and last flowering day and flowering duration as well as the traits specific leaf area, leaf dry matter content, area based leaf nitrogen and carbon content, carbon isotope discrimination (Δ13C), and the stomatal pore area index. 3. We found species-specific slopes of the beginning of leaf senescence along the elevational gradient. The peak of leaf senescence was uniformly delayed with increasing elevation across all species. Flowering phenology as well as leaf functional traits had a close relationship with leaf senescence and thus can be used to forecast species-specific responses to changes in abiotic conditions. High SLA and high leaf nitrogen were related to earlier senescence while high LDMC, high Δ13C and high SPI to later senescence. 4. Synthesis: The link between senescence, flowering phenology and plant functional traits will help to fine-tune predictions of future growing season length and ecosystem function. To date, most analyses are based on spring phenology and traits, for which data is more abundant than data on autumn senescence.
The timing of leaf senescence relates to flowering phenology and functional traits in 17 herbaceous species along elevational gradients
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Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts
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Functional CRISPR Screen Identifies AP1-associated Enhancer regulating FOXF1 to modulate Oncogene-Induced Senescence
GEO Series GSE112458. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series3 - Chromatin profiles, ChIP-seq)
GEO Series GSE207822. Homo sapiens. 40 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Pleiotrophic function of BAFF to promote a senescence-associated secretome and growth arrest
GEO Series GSE213993. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Long non-coding RNAs and their potential function in postharvest senescence of Sparassis latifolia packaged with oriented polypropylene film
GEO Series GSE226806. Sparassis latifolia. 12 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
In vitro caloric restriction induces protective genes and functional rejuvenation in senescent SAMP8 astrocytes
GEO Series GSE60388. Mus musculus. 12 samples. Type: Expression profiling by array.
Form follows function: Nuclear morphology as a quantifiable predictor of cellular senescence
GEO Series GSE293637. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series2 - chromatin sccessibility, ATAC-seq)
GEO Series GSE207818. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Decreased IGF1R Attenuates Senescence and Improves Function in Pancreatic beta-Cells
GEO Series GSE229709. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Distinct functions of wild-type and mutant Δ133p53α R273H differentially regulate glioblastoma aggressiveness and therapy-induced senescence
GEO Series GSE240377. Homo sapiens. 72 samples. Type: Expression profiling by high throughput sequencing.
Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.
GEO Series GSE81969. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Overactivation of Cdc42 GTPase Impairs the Cytotoxic Function of NK Cells from Old Individuals towards Senescent Fibroblasts
GEO Series GSE313986. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Endothelial Cell Senescence Stimulates Amyloid-β Phagocytosis and Barrier Function of Microglia Leading to Attenuation of Cognitive Impairment in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease
GEO Series GSE223394. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
A Dual Role of the Senescence Marker P16Ink4a in Liver Endothelial Cell Function
GEO Series GSE281665. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Post-GWAS functional analysis identifies CUX1 as a regulator of p16INK4a and cellular senescence
GEO Series GSE186528. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeting CyclinD1-CDK6 to Mitigate Senescence-Driven Inflammation and Age Associated Functional Decline
GEO Series GSE304160. Mus musculus. 4 samples. Type: Other.
GATA6 induces cell senescence to exerts lung cancer suppressive function and denotes a therapeutic opportunity for GATA6 deficient lung cancer patients
GEO Series GSE147447. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation
GEO Series GSE98136. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
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