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35 results for “Galleria mellonella”
Figure 1. A in Effects of the pyrethroid insecticide deltamethrin on the hemocytes of Galleria mellonella
Figure 1. A- Prohemocyte, B- plasmatocyte, C- spherulocyte, D- oenocyte, and E- granulocyte in the last instar of G. mellonella.
Figure 3 in Effects of Ni (II) p-hydroxybenzoate with caffeine on metabolic, antioxidant, and biochemical parameters of model insect Galleria mellonella L. (Lepidoptera: Pyralidae)
Figure 3. Effects of Ni (II) p-hydroxybenzoate with caffeine on ion levels of Galleria mellonella. Bars represent the means (± SD) of four replicates. Means followed by the same letter are not significantly different (p> 0.05).
Figure 1 in Effects of Ni (II) p-hydroxybenzoate with caffeine on metabolic, antioxidant, and biochemical parameters of model insect Galleria mellonella L. (Lepidoptera: Pyralidae)
Figure 1. Effects of Ni (II) p-hydroxybenzoate with caffeine on metabolic enzyme activity of Galleria mellonella. Bars represent the means (±SD) of four replicates. Means followed by the same letter are not significantly different (p> 0.05).
Figure 2 in Genotoxic effects of oxyclozanide on hemocytes of Galleria mellonella (Lepidoptera: Pyralidae) larvae
Figure 2. Tail length (μm) in hemocytes of seventh instar larvae of G. mellonella. Bars represent the means (± SE) of four replicates. Means followed by different letters are significantly different from each other, p <0.05 (LSD Test).
Figure 4 in Genotoxic effects of oxyclozanide on hemocytes of Galleria mellonella (Lepidoptera: Pyralidae) larvae
Figure 4. Tail moment in hemocytes of seventh instar larvae of G. mellonella. Bars represent the means (± SE) of four replicates. Means followed by different letters are significantly different from each other, p <0.05 (LSD Test).
Figure 3 in Genotoxic effects of oxyclozanide on hemocytes of Galleria mellonella (Lepidoptera: Pyralidae) larvae
Figure 3. Tail DNA% in hemocytes of seventh instar larvae of G. mellonella. Bars represent the means (± SE) of four replicates. Means followed by different letters are significantly different from each other, p <0.05 (LSD Test).
Plantago major effects on the innate immunity of Galleria mellonella
<p>These data have been published for the purpose of better evaluation of the article titled "Immunosuppressive effect of <em>Plantago major</em> on the innate immunity of <em>Galleria mellonella</em>" by the referees. These data have been obtained as a result of experiments and all rights belong to the publishing author and the supporting organization. This study was supported by Çanakkale Onsekiz Mart University The Scientific Research Coordination Unit (Grant number: FBA-2020-325).</p>
Virulence of three Aspergillus species to the model insect Galleria mellonella and the contribution of ergot alkaloids to the pathogenic potential of Aspergillus leporis
<p>Opportunistically pathogenic fungi have varying potential to cause disease in animals. Factors contributing to their virulence include specialized metabolites, which is some cases evolved in contexts unrelated to pathogenesis. Specialized metabolites that increase fungal virulence in the model insect <em>Galleria mellonella</em> include the ergot alkaloids fumigaclavine C in <em>Aspergillus fumigatus</em> (syn. <em>Neosartorya fumigata</em>) and lysergic acid α-hydroxyethylamide (LAH) in the entomopathogen <em>Metarhizium brunneum</em>. Three species of <em>Aspergillus</em> recently found to accumulate high concentrations of LAH were investigated for their pathogenic potential in <em>G. mellonella</em>. A<em>spergillus leporis</em> was most virulent, <em>A. hancockii </em>was intermediate, and <em>A. homomorphus</em> had very little pathogenic potential. <em>Aspergillus leporis</em> and <em>A. hancockii </em>emerged from and sporulated on dead insects, thus completing their asexual life cycles. Inoculation by injection resulted in more lethal infections than did topical inoculation, indicating <em>A. leporis</em> and <em>A. hancockii</em> were pre-adapted for insect pathogenesis but lacked an effective means to breach the insect's cuticle. All three species accumulated LAH in infected insects, with <em>A. leporis</em> accumulating the most. Concentrations of LAH in <em>A. leporis</em> were similar to those observed in the entomopathogen <em>M. brunneum</em>. LAH was eliminated from <em>A. leporis</em> through a CRISPR/Cas9-based gene knockout, and the resulting strain had reduced virulence to <em>G. mellonella</em>. The data indicate <em>A. leporis</em> and <em>A. hancockii</em> have considerable pathogenic potential and that LAH increases the virulence of <em>A. leporis</em>.</p>
Data from: The effect of inactivated bacteria on the redox status of larvae of the wax moth Galleria mellonella
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Data from: Does immune priming in Galleria mellonella reveal plastic mechanisms for survival?
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Virulence of three Aspergillus species to the model insect Galleria mellonella and the contribution of ergot alkaloids to the pathogenic potential of Aspergillus leporis
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Role of the intestinal microbiome in polyethylene degradation by caterpillar larva of the greater wax moth (Galleria mellonella)
<p>Recently, a few insects, including the caterpillar larva of the greater wax moth <i>Galleria</i><i> mellonella</i>, have been identified as avid "plastivores". Interestingly, these caterpillars are able to ingest and metabolize polyethylene at unprecedented rates. While it appears that <i>G. mellonella</i> plays an important role in the biodegradation process, the contribution of its intestinal microbiome remains poorly understood and contested. In a series of experiments, we present strong evidence of an intricate relationship between an intact microbiome, low density polyethylene (LDPE) biodegradation, and the production of glycol as a metabolic by-product. First, we biochemically confirmed that <i>G. mellonella</i> larvae consume and metabolize LDPE, as individual caterpillars fed on polyethylene excreted glycol, but those excretions are reduced by antibiotic treatment. Further, while the gut bacterial communities remain relatively stable regardless of diet, we show that during the early phases of feeding on LDPE (24-72 hrs), caterpillars exhibit increased microbial abundance relative to those starved or fed on their natural honeycomb diet. Finally, by isolating and growing gut bacteria with polyethylene as their exclusive carbon source for over one year, we identified microorganisms in the genus <i>Acinetobacter</i> that appear to be involved in this biodegradation process. Taken collectively, our study indicates that during short term exposure, the intestinal microbiome of <i>G. mellonella </i>is intricately associated with polyethylene biodegradation <i>in vivo</i>.</p>
Transcriptome analysis and functional study of phospholipase A2 in Galleria mellonella larvae lipid metabolism in response to envenomation by an ectoparasitoid, Iseropus kuwanae
<p>The file is the raw data of "Transcriptome analysis and functional study of phospholipase A2 in <em>Galleria mellonella</em> larvae lipid metabolism in response to envenomation by an ectoparasitoid, <em>Iseropus kuwanae</em>".</p>
Data from: Using the wax moth larva Galleria mellonella infection model to detect emerging bacterial pathogens
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Role of the intestinal microbiome in polyethylene degradation by caterpillar larva of the greater wax moth (Galleria mellonella)
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Data from: Independent and interactive effects of immune activation and larval diet on adult immune function, growth and development in the greater wax moth (Galleria mellonella)
Organisms in the wild are likely to face multiple immune challenges as well as additional ecological stressors, yet their interactive effects on immune function are poorly understood. Insects are found to respond to cues of increased infection risk by enhancing their immune capacity. However, such adaptive plasticity in immune function may be limited by physiological and environmental constraints. Here, we investigated the effects of two environmental stressors – poor larval diet and an artificial parasite-like immune challenge at the pupal stage – on adult immune function, growth and development in the greater wax moth (Galleria mellonella). Males whose immune system was activated with an artificial parasite-like immune challenge had weaker immune response – measured as strength of encapsulation response – as adults compared to the control groups, but only when raised in highnutrition larval diet. Immune activation did not negatively affect adult immune response in males reared in low-nutrition larval diet, indicating that poor larval diet improved the capacity of the insects to respond to repeated immune challenges. Low-nutrition larval diet also had a positive independent effect on immune capacity in females, yet it negatively affected development time and adult body mass in both sexes. As in the nature immune challenges are rarely isolated, and adverse nutritional environment may indicate an elevated risk of infection, resilience to repeated immune challenges as a response to poor nutritional environment could provide a significant fitness advantage. This study highlights the importance of considering environmental context when investigating the effects of immune activation in insects.
Figure 1 in Genotoxic effects of oxyclozanide on hemocytes of Galleria mellonella (Lepidoptera: Pyralidae) larvae
Figure 1. The comet assay images (20x) showing DNA damage in hemocytes of seventh instar larvae of G. mellonella reared on diet with oxyclozanide. (a) Control, (b) 0.003, (c) 0.03, (d) 0.3 g, and (e) 1.5% oxyclozanide concentration. The bar is 50 μm.
The Changes in Mitochondrial Morphology and Physiology Accompanying Apoptosis in Galleria mellonella (Lepidoptera) Immunocompetent Cells during Conidiobolus coronatus (Entomophthorales) Infection
<p>The raw data in published manuscript <a href="https://doi.org/10.3390/ijms241210169">https://doi.org/10.3390/ijms241210169</a></p>
Data from: Independent and interactive effects of immune activation and larval diet on adult immune function, growth and development in the greater wax moth (Galleria mellonella)
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Data from: Intra- and trans-generational effects of larval diet on susceptibility to an entomopathogenic fungus, Beauveria bassiana, in the greater wax moth, Galleria mellonella
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