Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
27
datasets available to search
ShareScore release 0.9.0
Dataset results
27 results for “Gene Retention”
Data from: The consequences of genetic variation in male sex peptide gene-expression levels for SP retention and egg laying in female Drosophila
The accessory gland proteins (Acps) that male Drosophila melanogaster produce and transfer to females during copulation are key to male and female fitness. One Acp, the sex peptide (SP), is largely responsible for a dramatic increase in female egg laying and decrease in female receptivity after copulation. While genetic variation in male SP expression levels correlate with refractory period duration in females, it is unknown whether male SP expression influences female egg laying or if any effect of SP is mediated by SP retention in the female reproductive tract. Here we measured the amount of SP retained in the female reproductive tract after mating and female egg laying after copulating with virgin males. We found no correlation between male SP expression levels and egg laying, or the amount of SP in the female reproductive tract after mating. Additionally, the amount of SP retained in the female did not influence egg laying. These finding suggests that additional factors, such as variation in other Acps, are important for the retention of SP in females and its quantitative effects on egg laying. It also shows that egg laying and refractory period response to SP is at least partially uncoupled.
Data from: The consequences of genetic variation in male sex peptide gene-expression levels for SP retention and egg laying in female Drosophila
Open the record for dataset details and reuse information.
Exploring whole-genome duplicate gene retention with complex genetic interaction analysis
<p>Whole-genome duplication<b> </b>has played a central role in genome evolution of many organisms, including the human genome. Most duplicated genes are eliminated and factors that influence the retention of persisting duplicates remain poorly understood. Here, we describe a systematic complex genetic interaction analysis with yeast paralogs derived from the whole-genome duplication event. Mapping digenic interactions for a deletion mutant of each paralog and trigenic interactions for the double mutant provides insight into their roles and a quantitative measure of their functional redundancy. Trigenic interaction analysis distinguishes two classes of paralogs, a more functionally divergent subset and another that retained more functional overlap. Gene feature analysis and modeling suggest that evolutionary trajectories of duplicated genes are dictated by combined functional and structural entanglement factors.</p>
Exploring whole-genome duplicate gene retention with complex genetic interaction analysis
Open the record for dataset details and reuse information.
Data from: Subfunctionalization of peroxisome proliferator response elements accounts for retention of duplicated fabp1 genes in zebrafish
Open the record for dataset details and reuse information.
Paternal poly(ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression
GEO Series GSE55009. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Dynamic intron retention modulates gene expression in the monocytic differentiation pathway
GEO Series GSE168231. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Gene expression and intron retention analysis of 15.5K-knockdown human cells
GEO Series GSE182759. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Targeted intron retention and excision for rapid gene regulation in response to neuronal activity
GEO Series GSE89771. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Spatio-temporal X-linked gene reactivation in the mouse germline reveals site-specific retention of epigenetic silencing [WGBS]
GEO Series GSE243941. Mus musculus. 2 samples. Type: Methylation profiling by high throughput sequencing.
Paternal poly(ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression [PJ34_sperm_MNaseb]
GEO Series GSE56282. Mus musculus. 19 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Gene expression and intron retention analysis of bktRNA1-depleted human cells
GEO Series GSE160515. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Paternal poly(ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression [Parg(110)_KO_sperm_MNase]
GEO Series GSE56281. Mus musculus. 25 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Genome-wide analysis of gene expression and intron retention during development in a U12-type splicing-deficient zebrafish mutant
GEO Series GSE53935. Danio rerio. 8 samples. Type: Expression profiling by high throughput sequencing; Expression profiling by array.
Stress-induced transcriptional readthrough into neighboring genes is linked to intron retention
GEO Series GSE197536. Mus musculus. 26 samples. Type: Expression profiling by high throughput sequencing; Other.
Gene expression and intron retention analysis of ZCRB1-knockdown human cells
GEO Series GSE182830. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide analysis of gene expression and intron retention during deveopment in a U12-type splicing-deficient zebrafish mutant [microarray]
GEO Series GSE53934. Danio rerio. 6 samples. Type: Expression profiling by array.
Paternal poly(ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression [Parg(110)_KO_2CE]
GEO Series GSE56184. Mus musculus. 18 samples. Type: Expression profiling by array.
Paternal poly(ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression [PJ34_2CE]
GEO Series GSE56182. Mus musculus. 17 samples. Type: Expression profiling by array.
Spatio-temporal X-linked gene reactivation in the mouse germline reveals site-specific retention of epigenetic silencing
GEO Series GSE243943. Mus musculus. 127 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.