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ShareScore release 0.9.0
Dataset results
45 results for “Graft dysfunction”
Sodium Nitrite in Lung Transplant Patients to Minimize the Risk of Pulmonary Graft Dysfunction
ClinicalTrials.gov study NCT01715883. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Treatment with 3-aminobenzamide during ex vivo lung perfusion of damaged rat lungs reduces graft injury and dysfunction after transplantation
<p>Ex vivo lung perfusion (EVLP) with pharmacological reconditioning may increase donor lung utilization for transplantation (LTx). 3-Aminobenzamide (3-AB), an inhibitor of poly (ADP-ribose) polymerase (PARP), reduces ex vivo lung injury in rat lungs damaged by warm ischemia (WI). Here we determined the effects of 3-AB reconditioning on graft outcome after LTx. Three groups of donor lungs were studied: Control (Ctrl): 1 hour WI + 3 hours cold ischemia (CI) + LTx; EVLP: 1 hour WI + 3 hours EVLP + LTx; EVLP + 3-AB: 1 hour WI + 3 hours EVLP + 3-AB (1 mg<sup>.</sup>mL<sup>−1</sup>) + LTx. Two hours after LTx, we determined lung graft compliance, edema, histology, neutrophil counts in bronchoalveolar lavage (BAL), mRNA levels of adhesion molecules within the graft, as well as concentrations of interleukin-6 and 10 (IL-6, IL-10) in BAL and plasma. 3-AB reconditioning during EVLP improved compliance and reduced lung edema, neutrophil infiltration, and the expression of adhesion molecules within the transplanted lungs. 3-AB also attenuated the IL-6/IL-10 ratio in BAL and plasma, supporting an improved balance between pro- and anti-inflammatory mediators. Thus, 3-AB reconditioning during EVLP of rat lung grafts damaged by WI markedly reduces inflammation, edema, and physiological deterioration after LTx, supporting the use of PARP inhibitors for the rehabilitation of damaged lungs during EVLP.</p>
Belatacept as a Replacement for CNIs 3 to 12 Months Post-transplantation in Patients With Early Graft Dysfunction
ClinicalTrials.gov study NCT05562869. IPD Sharing: NO. Countries: 1. Publications: 2.
Protective Effect of PCSK9 Inhibitor Against Negative Inflammatory Response and Organ Dysfunction After Coronary Artery Bypass Grafting (PANDA VIII)
ClinicalTrials.gov study NCT06730802. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
Quantifying Physical and Biochemical Factors That Contribute to Primary Graft Dysfunction After Lung Transplantation
ClinicalTrials.gov study NCT01151826. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease
ClinicalTrials.gov study NCT04772768. IPD Sharing: Not stated. Countries: 1. Publications: 1.
CNI Transient Replacement by Belatacept From 3 to 12 Months Post Transplantation in Patients With Early Graft Dysfunction
ClinicalTrials.gov study NCT04013620. IPD Sharing: NO. Countries: 1. Publications: 2.
Measurement of Extravascular Lung Water to Detect and Predict Primary Graft Dysfunction Following Lung Transplant
ClinicalTrials.gov study NCT01605214. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation
ClinicalTrials.gov study NCT00457847. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Risk Factors That Increase the Chance of Developing Primary Graft Dysfunction After Lung Transplantation
ClinicalTrials.gov study NCT00552357. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Prospective, Randomized Controlled Trial of Stent Graft and Drug Coated Balloon Treatment for Recurrent Cephalic Arch Stenosis in Dysfunctional Arteriovenous-venous Fistula
ClinicalTrials.gov study NCT05360394. IPD Sharing: NO. Countries: 2. Publications: 8.
Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer
ClinicalTrials.gov study NCT00080808. IPD Sharing: Not stated. Countries: 1. Publications: 1.
RENAL: TNF-alpha Inhibitor for Improving Renal Dysfunction and Primary Graft Dysfunction After Lung Transplant
ClinicalTrials.gov study NCT05950724. IPD Sharing: NO. Countries: 1. Publications: 15.
Treatment with 3-aminobenzamide during ex vivo lung perfusion of damaged rat lungs reduces graft injury and dysfunction after transplantation
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Supplementary Materials article : Risk Estimation of Severe Primary Graft Dysfunction in Heart Transplant Recipients Using a Smartphone
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Repertaxin in Prevention of Primary Graft Dysfunction After Lung Transplantation
ClinicalTrials.gov study NCT00224406. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Borderline Changes in Renal Allografts: Molecular Diagnostics Identifies Risks for Graft Dysfunction
GEO Series GSE52694. Homo sapiens. 28 samples. Type: Expression profiling by array.
Salivary ZG16B expression loss marks onset of oral Chronic Graft-Versus-Host Disease and exocrine gland dysfunction
GEO Series GSE180544. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
IL1β-dependent extravasation of pre-existing lung-restricted autoantibodies activates complement to promote primary graft dysfunction
GEO Series GSE211501. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Dysfunction of infiltrating cytotoxic CD8+ T cells within the graft promotes murine kidney allotransplant tolerance
GEO Series GSE252337. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.