Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
53
datasets available to search
ShareScore release 0.9.0
Dataset results
53 results for “HIF-1”
Data from: Pharmacological HIF-1 activation upregulates extracellular vesicle production synergistically with adiponectin through transcriptional induction and protein stabilization of T-cadherin
<p>Pharmacological activation of hypoxia-inducible factor 1alpha (HIF-1α), a hypoxia-responsive transcription factor, has attracted increasing attention due to its efficacy not only in renal anemia but also in various disease models. Our study demonstrated that a HIF-1 activator enhanced exosome production from cultured endothelial cells synergistically with adiponectin, an adipocyte-derived factor, through both transcriptional induction and posttranscriptional stabilization of an adiponectin binding partner, T-cadherin. Increased exosome levels were observed in wild-type mice but not in T-cadherin null mice after consecutive administration of roxadustat. Adiponectin- and T-cadherin-dependent increased exosome production may be involved in the pleiotropic effects of HIF-1 activators.</p>
Physical Exercise and Responses Measured by HIF-1 in COPD
ClinicalTrials.gov study NCT04955977. IPD Sharing: NO. Countries: 1. Publications: 9.
Hypoxia-inducible Factor-1 (HIF-1) Regulated Circulating Angiogenic Cells (CACs) Recruitment in Burn Wound Healing
ClinicalTrials.gov study NCT00796627. IPD Sharing: NO. Countries: 1. Publications: 1.
Data from: Pharmacological HIF-1 activation upregulates extracellular vesicle production synergistically with adiponectin through transcriptional induction and protein stabilization of T-cadherin
Open the record for dataset details and reuse information.
Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients With Intermittent Claudication
ClinicalTrials.gov study NCT00117650. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Human Liver Explants for HIF-1 Alpha Analysis/Comparison (HIF HCC)
ClinicalTrials.gov study NCT00866957. IPD Sharing: Not stated. Countries: 1. Publications: 32.
Circulating Stem Cells, SDF-1, HIF-1 and Sepsis's Indices in Emergency Abdominal Surgical Patients
ClinicalTrials.gov study NCT02589535. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Determination of Salivary Soluble Urokinase Plasminogen Activator Receptor (SuPAR), Hypoxia-inducible Factor-1 Alpha (HIF-1α), E-cadherin, Galectin 3, IL-4, IL-10 and TNF-α Levels in Individuals With
ClinicalTrials.gov study NCT06430450. IPD Sharing: NO. Countries: 0. Publications: 1.
Deubiquitinating enzyme mutagenesis screens identify a USP43 driven HIF-1 transcriptional response
GEO Series GSE252655. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing; Other.
NHR-49 controls a HIF-1 independent hypoxia adaptation pathway in Caenorhabditis elegans
GEO Series GSE166788. Caenorhabditis elegans. 18 samples. Type: Expression profiling by high throughput sequencing.
The role of HIF-1 in beta-glucan induced response in myeloid cell
GEO Series GSE57206. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
HIF-1 directly induces TET3 expression to redistribute 5-hydroxymethylcytosine and induce erythroid gene expression in hypoxia [ChIP-seq]
GEO Series GSE142865. Homo sapiens. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
HIF-1 directly induces TET3 expression to redistribute 5-hydroxymethylcytosine and induce erythroid gene expression in hypoxia [5-hmC]
GEO Series GSE142869. Homo sapiens. 11 samples. Type: Methylation profiling by high throughput sequencing.
HIF-1 regulates pathogenic T cells in lupus skin disease (scRNA-Seq)
GEO Series GSE229405. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing; Other.
Deubiquitinating enzyme mutagenesis screens identify a USP43 driven HIF-1 transcriptional response [CRISPR]
GEO Series GSE252651. Homo sapiens. 4 samples. Type: Other.
DNA demethylase ALKBH1 promotes adipogenic differentiation via regulation of HIF-1 signaling
GEO Series GSE177059. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiling of Mec-1 cells upon chronic silencing of HIF-1a
GEO Series GSE77173. Homo sapiens. 2 samples. Type: Expression profiling by array.
HIF-1 regulates pathogenic T cells in lupus skin disease (bulk RNA-Seq)
GEO Series GSE229403. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide HIF-1 binding sites in HepG2 cells
GEO Series GSE16347. Homo sapiens. 14 samples. Type: Genome binding/occupancy profiling by genome tiling array.
miRNA-150_R-1 mediates the HIF-1/ErbB signaling pathway to regulate the adhesion of endometrial epithelial cells in cows experiencing retained placenta
GEO Series GSE214588. Bos taurus. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.