Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
19
datasets available to search
ShareScore release 0.9.0
Dataset results
19 results for “HLA-B”
A molecular basis for the presentation of phosphorylated peptides by HLA-B antigens (ANNOTATED MS2 SPECTRA OF PHOSPHOPEPTIDES)
<p>Phosphopeptides identified from the immunopeptidome of the C1R-B*40 cell line. </p> <p>Phosphopeptides identified from the proteome of the C1R-B*40 cell line. </p> <p>Phosphopeptides identified from the immunopeptidome of the GR cell line. </p>
Clinical Utility Of Genetic Screening For HLA-B*5701, On Susceptibility To Abacavir Hypersensitivity
ClinicalTrials.gov study NCT00340080. IPD Sharing: Not stated. Countries: 19. Publications: 1.
Prospective Epidemiological Study Of The Prevalence Of HLA-B*5701
ClinicalTrials.gov study NCT00453440. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Sorted Bulk and KK10-specific CD8+ T cells from HLA-B*2705 HIV chronic progressors before and after KK10 peptide stimulation
GEO Series GSE56775. Homo sapiens. 12 samples. Type: Expression profiling by array.
The HLA-B*35 allele modulates ER stress, inflammation and proliferation in PBMCs from Limited Cutaneous Systemic Sclerosis patients
GEO Series GSE73355. Homo sapiens. 15 samples. Type: Expression profiling by array.
HLA-B*46 associates with rapid HIV disease progression in Asian cohorts and prominent differences in NK cell phenotype
GEO Series GSE192384. Homo sapiens. 112 samples. Type: Expression profiling by high throughput sequencing.
CD8 T cells cross-restricted by HLA-B*57 and HLA-E*01 recognize HIV Gag with different functional profiles [dataset 2]
GEO Series GSE306023. Homo sapiens. 29 samples. Type: Expression profiling by high throughput sequencing.
Data from: Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity
The highly polymorphic human leukocyte antigen (HLA) class I molecules present peptide antigens to CD8+ T cells, inducing immunity against infections and cancers. Quality control mediated by peptide loading complex (PLC) components is expected to ensure the cell surface expression of stable peptide-HLA class I complexes. This is exemplified by HLA-B*08:01 in primary human lymphocytes, with both expression level and half-life at the high end of the measured HLA-B expression and stability hierarchies. Conversely, low expression on lymphocytes is measured for three HLA-B allotypes that bind peptides with proline at position 2, which are disfavored by the transporter associated with antigen processing. Surprisingly, these lymphocyte-specific expression and stability differences become reversed or altered in monocytes, which display larger intracellular pools of HLA class I than lymphocytes. Together, the findings indicate that allele and cell-dependent variations in antigen acquisition pathways influence HLA-B surface expression levels, half-lives and receptivity to exogenous antigens.
Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity Syndrome
ClinicalTrials.gov study NCT02550080. IPD Sharing: Not stated. Countries: 1. Publications: 0.
HLA-B*5801 Screening to Prevent Allopurinol-induced Severe Cutaneous Adverse Reaction
ClinicalTrials.gov study NCT03046914. IPD Sharing: Not stated. Countries: 1. Publications: 0.
HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-Effectiveness
ClinicalTrials.gov study NCT07369622. IPD Sharing: YES. Countries: 0. Publications: 0.
HLA-B*5701 And Hypersensitivity To Abacavir
ClinicalTrials.gov study NCT00373945. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of Patient Management in HIV-1 Infected Patients Found to Have the Genetic Marker HLA-B*5701
ClinicalTrials.gov study NCT00435838. IPD Sharing: Not stated. Countries: 7. Publications: 0.
Prospective Epidemiological Study Of The Prevalence Of HLA-B*5701 In HIV-1 Infected Patients
ClinicalTrials.gov study NCT00481390. IPD Sharing: Not stated. Countries: 5. Publications: 0.
Sorted Bulk and KK10-specific CD8+ T cells from HLA-B*2705 HIV elite controllers before and after KK10 peptide stimulation
GEO Series GSE56971. Homo sapiens. 12 samples. Type: Expression profiling by array.
Data from: Empty conformers of HLA-B preferentially bind CD8 and regulate CD8+ T cell function
Open the record for dataset details and reuse information.
Data from: Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity
Open the record for dataset details and reuse information.
Data from: Selected HLA-B allotypes are resistant to inhibition or deficiency of the transporter associated with antigen processing (TAP)
Open the record for dataset details and reuse information.
CD8 T cells cross-restricted by HLA-B*57 and HLA-E*01 recognize HIV Gag with different functional profiles [dataset 1]
GEO Series GSE306022. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing; Other.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.