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1,202 results for “HPV”
Human papillomavirus (HPV) detection in vaginal self-samples: evaluation of eNat® as an alternative suspension medium to ThinPrep®PreservCyt® for vaginal swabs
<p>Dataset 1: HPV positivity on cervical and vaginal self-samples with different HPV real-time PCR assays</p> <p>Dataset 2: hrHPV viral load in cervical and vaginal self-samples</p> <p>Datakey 1: HPV positivity on cervical and vaginal self-samples with different HPV real-time PCR assays</p> <p>Datakey 2: hrHPV viral load in cervical and vaginal self-samples</p>
ASPH and Hypoxia Marker Expression in Head and Neck Carcinomas: Implications for HPV-Associated Tumours
<p><strong>Data open:</strong> file with parametres used for the multivariate evaluation. </p>
Long Term Immune Memory Responses to HPV Vaccination Following 2 vs 3 Doses of Quad-HPV Vaccine
ClinicalTrials.gov study NCT02968420. IPD Sharing: NO. Countries: 1. Publications: 2.
Self-Testing Options in the Era of Primary HPV Screening for Cervical Cancer Trial
ClinicalTrials.gov study NCT04679675. IPD Sharing: YES. Countries: 1. Publications: 2.
ATUAÇÃO DO ENFERMEIRO NOS CUIDADOS À MULHER COM HPV
<p>O Papilomavírus Humano (HPV) é um vírus de agente etiológico, responsável pelos tumores benignos e malignos e pode ser transmitido pela via sexual a infecção. <strong>Objetivo</strong>: Compreender a atuação do enfermeiro nos cuidados à mulher com HPV. <strong>Métodos</strong>: utilizou-se de revisão de literatura sistemática com as seguintes palavras chave: HPV, atuação do enfermeiro, CA uterino. Foi realizada uma busca nas bases de dados eletrônicas que contou com o levantamento de publicações cientificas sobre a temática proposta junto a base de dados na Biblioteca Virtual de Saúde (BVS), Medical Literature Analysis and Retrieval System Online (MEDLINE) e Scientific Electronic Library Online (SciIELO) em publicações entre 2018 até 2023. <strong>Resultados</strong>: por intermédio dos estudos, resultou 8.558 artigos pesquisados sobre atuação do enfermeiro nos cuidados à mulher com HPV, as maiores quantidades entre os achados destacaram-se uma compreensão sobre o HPV na sua transmissibilidade e as evidências científicas quanto à apresentação na atuação do enfermeiro nos cuidados a mulher com HPV. <strong>Conclusão</strong>: conclui-se que é essencial as medidas de promoção e prevenção a saúde da mulher, na educação em relação aos cuidados com a mesma, vítima de HPV, ou seja, esse vírus segue de forma conhecida através da relação sexual pela população.</p>
Repurposing Type I-A CRISPR-Cas3 for a robust diagnosis of human papillomavirus (HPV)
<p>R-loop-triggered collateral single-stranded DNA (ssDNA) nuclease activity within Class 1 Type I CRISPR-Cas systems holds immense potential for nucleic acid detection. However, the hyperactive ssDNase activity of Cas3 introduces unwanted noise and false-positive results. In this study, we identified a novel Type I-A Cas3 variant derived from <em>Thermococcus siculi</em>, which remains in an auto-inhibited state until it is triggered by Cascade complex and R-loop formation. This Type I-A CRISPR-Cas3 system not only exhibits an expanded protospacer adjacent motif (PAM) recognition capability but also demonstrates remarkable intolerance towards mismatched sequences. Furthermore, it exhibits dual activation modes—responding to both DNA and RNA targets. The culmination of our research efforts has led to the development of the Hyper-Active-Verification Establishment (HAVE, 惠父). This innovation enables swift and precise <em>human papillomavirus</em> (HPV) diagnosis in clinical samples, providing a robust molecular diagnostic tool based on the Type I-A CRISPR-Cas3 system. Our findings contribute to understanding type I-A CRISPR-Cas3 system regulation and facilitate the creation of advanced diagnostic solutions with broad clinical applicability.</p>
Identifying one-to-one communication themes on HPV and HPV vaccination
<p>The aim of this study is to examine the factors that impact communication between doctors, young adolescents, parents, and caregivers when discussing HPV vaccination recommendations. We are interested in understanding how different topics are discussed based on patient characteristics. Specifically, we would like to explore the influence of factors such as religion, country of origin, educational level, and gender.</p> <p>Survey was carried out in the framework of the European project PROTECT-EUROPE (EU4H-1, Project ID 101080046). PROTECT-EUROPE is an EU4Health Project that champions gender-neutral vaccination programme in EU Member States to provide protection for everyone against cancers caused by HPV e.g. cervical, anal, penile, vaginal, vulval and oropharyngeal.</p>
Database for comparison between Hybrid Capture and PCR techniques for HPV-HR detection
<p>This database displays the results from the HPV-HR detection with the gold standard technique Hybrid Capture 2 (HC2) and different PCR-based techniques. These results are compared in order to determine the degree of agreement between theses techniques. </p>
Data for: HPV upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer
<p>The membrane-associated RING-CH-type finger ubiquitin ligase MARCHF8 is a human homolog of the viral ubiquitin ligases Kaposi's sarcoma herpesvirus K3 and K5 that promote host immune evasion. Previous studies have shown that MARCHF8 ubiquitinates several immune receptors, such as the major histocompatibility complex II and CD86. While human papillomavirus (HPV) does not encode any ubiquitin ligase, the viral oncoproteins E6 and E7 are known to regulate host ubiquitin ligases. Here, we report that MARCHF8 expression is upregulated in HPV-positive head and neck cancer (HNC) patients but not in HPV-negative HNC patients compared to normal individuals. The MARCHF8 promoter is highly activated by HPV oncoprotein E6-induced MYC/MAX transcriptional activation. The knockdown of MARCHF8 expression in human HPV-positive HNC cells restores cell surface expression of the tumor necrosis factor receptor superfamily (TNFRSF) death receptors, FAS, TRAIL-R1, and TRAIL-R2, and enhances apoptosis. MARCHF8 protein directly interacts with and ubiquitinates the TNFRSF death receptors. Further, MARCHF8 knockout in mouse oral cancer cells expressing HPV16 E6 and E7 augments cancer cell apoptosis and suppresses tumor growth in vivo. Our findings suggest that HPV inhibits host cell apoptosis by upregulating MARCHF8 and degrading TNFRSF death receptors in HPV-positive HNC cells.</p>
HPV Vaccine Immunity in High-risk Women
ClinicalTrials.gov study NCT04590521. IPD Sharing: YES. Countries: 1. Publications: 1.
Increasing Optimal Use of HPV Vaccination in Primary Care
ClinicalTrials.gov study NCT04180462. IPD Sharing: NO. Countries: 1. Publications: 0.
A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents, and Young Adults
ClinicalTrials.gov study NCT00798265. IPD Sharing: YES. Countries: 1. Publications: 3.
Concomitant HPV Vaccination and HPV Screening HPV Infection and Cervical Cancer in Sweden
ClinicalTrials.gov study NCT04910802. IPD Sharing: YES. Countries: 1. Publications: 1.
Increasing HPV Vaccination in Community-Based Pediatric Practices
ClinicalTrials.gov study NCT03399396. IPD Sharing: YES. Countries: 1. Publications: 1.
Marketability of a Technology-based Intervention to Increase HPV Vaccination
ClinicalTrials.gov study NCT03497936. IPD Sharing: NO. Countries: 1. Publications: 1.
A Post Marketing Surveillance (PMS) Study to Monitor the Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine in Female Chinese Subjects
ClinicalTrials.gov study NCT03438006. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Post-treatment Surveillance in HPV+ Oropharyngeal SCC
ClinicalTrials.gov study NCT04965792. IPD Sharing: YES. Countries: 1. Publications: 1.
Interactive, Health Literacy Promoting Text Messages and HPV Vaccine Completion In Minority Adolescents
ClinicalTrials.gov study NCT02236273. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Efficacy, Immunogenicity and Safety of GSK Biologicals' HPV GSK 580299 Vaccine in Healthy Chinese Female Subjects
ClinicalTrials.gov study NCT00779766. IPD Sharing: YES. Countries: 1. Publications: 12.
Evaluation of Immunogenicity and Safety of Two 2-dose Human Papillomavirus (HPV) Vaccine Schedules in 9-14 Year Old Girls
ClinicalTrials.gov study NCT01381575. IPD Sharing: YES. Countries: 5. Publications: 4.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.