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59 results for “HSP70”
Fig. 5 in Expression profile of two HSP70 chaperone proteins in response to extreme thermal acclimation in Xestia c-nigrum (Lepidoptera: Noctuidae)
Fig. 5. Xc-HSC70 mRNA expression profiles induced by cold (−7 to 5 °C) and heat (37 to 47 °C) in 2nd, 3rd, 4th, 5th, and 6th instars and pupae of Xestia cnigrum. The relative quantities indicate the levels of the HSC70 gene transcript normalized against transcript levels of β-actin as an internal standard and compared with the transcript levels of the untreated control at 25 °C. An asterisk indicates a significant difference between the control and heat shock conditions (significant, * P <0.05). The data are denoted as the mean ± SEM (error bar).
Fig. 7 in Expression profile of two HSP70 chaperone proteins in response to extreme thermal acclimation in Xestia c-nigrum (Lepidoptera: Noctuidae)
Fig. 7. Expression levels of 2 HSP70s at different developmental stages relative to expression levels in 2nd instars at 25 °C. The data are denoted as the mean ± SEM (error bar), and the different lowercase or uppercase letters indicate a significant differenwce in the means as assessed using multi-comparison tests (P <0.05).
Fig. 4 in Expression profile of two HSP70 chaperone proteins in response to extreme thermal acclimation in Xestia c-nigrum (Lepidoptera: Noctuidae)
Fig. 4. Phylogenetic tree of Xc-HSC70 and Xc-HSP70 amino acid sequences from different species. A 3-letter code has been included to indicate the order name of the corresponding insect and vertebrate orders (COL = Coleoptera, LEP = Lepidoptera, DIP = Diptera, HYM = Hymenoptera, and VER =Vertebrata). The values indicated on the branches correspond to bootstrap percentages (BP).
Fig. 3 in Expression profile of two HSP70 chaperone proteins in response to extreme thermal acclimation in Xestia c-nigrum (Lepidoptera: Noctuidae)
Fig. 3. Schematic structure of the Xc-HSC70 gene. Exons are shown as boxes in which white boxes represent untranslated regions, whereas the black boxes are the protein-coding exons; introns are indicated as lines between the boxes. The numbers above and below the drawing represent the sizes (base pairs) of each exon and intron, respectively. The start codon (ATG) and stop codon (TAA) are also indicated. The genomic DNA sequence of Xc-HSC70 has been deposited in GenBank under accession no. KF731994.
Fig. 2 in Expression profile of two HSP70 chaperone proteins in response to extreme thermal acclimation in Xestia c-nigrum (Lepidoptera: Noctuidae)
Fig. 2. Nucleotide and deduced amino acid sequences of the Xc-HSP70 gene. The signature sequences of the HSP70 family are shown in boxes, the nuclear localization signal sequence is underlined, the consensus sequence EEVD at the C-terminus is indicated in italics, and the start and stop codons are in bold. The nucleotides and amino acids are numbered along the lef and right margins. The sequence encoding Xc-HSP70 has been deposited in GenBank under accession no. HQ698836.
Fig. 1 in Expression profile of two HSP70 chaperone proteins in response to extreme thermal acclimation in Xestia c-nigrum (Lepidoptera: Noctuidae)
Fig. 1. Nucleotide and deduced amino acid sequences of Xc-HSC70. The signature sequences of the HSP70 family are shown in boxes, the nuclear localization signal sequence is underlined, the consensus sequence EEVD at the C-terminus is indicated in italics, and the start and stop codons are in bold. The nucleotides and amino acids are numbered along the lef and right margins. The sequence encoding Xc-HSC70 has been deposited in GenBank under accession no. KC844151.
Hsp70_entropic_pulling
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Data accompanying "HSP70 inhibits CHIP E3 ligase activity to maintain germline function in Caenorhabditis elegans" article.
<p>This work was funded by the National Science Centre, Poland (grant PRELUDIUM number 2021/41/N/NZ1/03086) (to P.T.) and by the Deutsche Forschungsgemeinschaft (DFG; German Research Foundation) under Germany’s Excellence Strategy – EXC 2030 – 390661388 and – FOR 5504 – project number 496650118 (to T.H.). M.T.P. received support by the Cologne Graduate School of Aging Research. N.A.S., A.S., K.J., and M.N. were supported by the International Institute of Molecular and Cell Biology in Warsaw.</p>
Data from: Research Note: Possible influence of thermal selection on patterns of HSP70 and HSP90 gene polymorphisms in Thai indigenous and local chicken breeds and red junglefowls
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Knockout of Hsp70 genes significantly affects locomotion speed and gene expression in leg skeletal muscles of Drosophila melanogaster
<p>Supplemental data for a study <strong>Knockout of </strong><em><strong>Hsp70 </strong></em><strong>genes significantly affects locomotion speed and gene expression in leg skeletal muscles of </strong><em><strong>Drosophila melanogaster </strong></em>(Physiol Genomics 56: 567–575, 2024.<br><a href="https://doi.org/10.1152/physiolgenomics.00143.2023">https://doi.org/10.1152/physiolgenomics.00143.2023</a> )</p>
Reactogenicity and Immunogenicity of Cervico-vaginal CN54gp140-hsp70 Conjugate Vaccine
ClinicalTrials.gov study NCT01285141. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Fig. 6 in Expression profile of two HSP70 chaperone proteins in response to extreme thermal acclimation in Xestia c-nigrum (Lepidoptera: Noctuidae)
Fig. 6. Xc-HSP70 mRNA expression profiles induced by cold (−7 to 5 °C) and heat (37 to 47 °C) in 2nd, 3rd, 4th, 5th, and 6th instars and pupae of Xestia cnigrum. The relative quantities indicate the levels of the HSP70 gene transcript normalized against transcript levels of β-actin as an internal standard and compared with the transcript levels of the untreated control at 25 °C. An asterisk indicates a significant difference between the control and heat shock conditions (significant, * P <0.05). The data are denoted as the mean ± SEM (error bar).
Evolution of sex-specific heat stress tolerance and larval Hsp70 expression in populations of Drosophila melanogaster adapted to larval crowding
<p class="BodyA">The ability to tolerate temperature stress is an important component of adult fitness. In holometabolous insects like <i>Drosophila melanogaster,</i> adult stress resistance can be affected by growth conditions experienced during the larval stages. While evolution under crowded larval conditions is known to lead to the correlated evolution of many adult traits, its consequences on adult heat stress tolerance have not been investigated. Therefore, in the present study, we assessed the adult heat stress tolerance in populations of <i>D.</i><i> </i><i>melanogaster</i> adapted to a stressful larval crowding environment. We used replicate populations of <i>D.</i><i> </i><i>melanogaster</i>, selected for adaptation to larval crowding stress (MCUs), for more than 230 generations, and their respective controls (MBs). Larvae from selected and control populations were grown under crowded and uncrowded conditions and their adult heat shock resistance at two different temperatures was measured. Further, we compared Hsp70 expression in crowded and uncrowded larvae of both populations and also measured the Hsp70 expression after a mild-heat treatment in adults of selected and control populations. Our results showed that adaptation to larval crowding leads to the evolution of Hsp70 gene expression in larval stages and improves adult heat-stress tolerance ability in males, but not in females. </p>
Data from: Hsp70 protein levels and thermotolerance in Drosophila subobscura: a reassessment of the thermal co-adaptation hypothesis
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Evolution of sex-specific heat stress tolerance and larval Hsp70 expression in populations of Drosophila melanogaster adapted to larval crowding
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Proteostasis perturbation of N-Myc by HSP70 inhibition improves treatment in neuroendocrine prostate cancer I
GEO Series GSE249916. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Cytosolic splice isoform of Hsp70 nucleotide exchange factor Fes1 is required for the degradation of misfolded proteins in yeast
GEO Series GSE78136. Saccharomyces cerevisiae. 18 samples. Type: Expression profiling by high throughput sequencing.
HSP70 binds to specific non-coding RNA and regulates human RNA polymerase III
GEO Series GSE191245. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
HSP70 binds RNA and regulates transcription by RNA Polymerase III [FLASH-seq]
GEO Series GSE191242. Homo sapiens. 6 samples. Type: Other.
Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity is compromised
GEO Series GSE178352. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
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