Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
57
datasets available to search
ShareScore release 0.9.0
Dataset results
57 results for “Haematopoiesis”
Exome-wide association analysis (ExWAS) of clonal haematopoiesis in 136,401 Admixed Americans and 416,118 Europeans
<p>We performed exome-wide association analysis (ExWAS) of germline genetic variants identified from whole-exome sequencing (WES) to identify novel inherited genetic determinants of clonal haematopoiesis (CH). Here, we provide the summary statistics from ExWAS CH performed on Admixed Americans recruited to the Mexico City Prospective Study (MCPS), Europeans recruited to the United Kingdom Biobank (UKB), and cross-ancestry meta-analysis of Admixed Americans and Europeans. Analyses was performed with REGENIE software (Firth's logistic regression), Fisher's exact test, and METAL software (inverse variance-weighted average method to derive effect size and <em>P</em>-value method to derive P value), respectively.</p> <p> </p> <p>In version 1 of this repository, UKB variants (*_UKB.tsv) with minor allele frequency (MAF) 1% or more were uploaded. In version 2, this is now rectified so that rare variants with MAF of 0.1% or more were uploaded. This threshold now matches the MCPS (*_MCPS.tsv) and UKB-MCPS meta-analysis summary statistics (*_MCPS-UKB_meta-analysis.tsv)</p>
Gene-collapsing analysis of clonal haematopoiesis in 136,401 Admixed Americans and 416,118 Europeans
<p>We performed gene-collapsing (gene burden) analysis of germline genetic variants identified from whole-exome sequencing (WES) to identify novel inherited genetic determinants of clonal haematopoiesis (CH). Here, we provide the summary statistics from CH gene-collapsing analysis performed on Admixed Americans recruited to the Mexico City Prospective Study (MCPS), Europeans recruited to the United Kingdom Biobank (UKB), and cross-ancestry meta-analysis of Admixed Americans and Europeans. Analyses was performed with <span>Fisher'</span>s exact test (for MCPS and UKB analysis) and Cochran–Mantel–Haenszel test (for meta-analysis).</p>
Age-related Clonal Haematopoiesis in an HIV Evaluation Cohort (ARCHIVE)
ClinicalTrials.gov study NCT04641013. IPD Sharing: NO. Countries: 1. Publications: 1.
Aberrant haematopoiesis in Dnmt2 mutant mice [array]
GEO Series GSE65302. Mus musculus. 2 samples. Type: Expression profiling by array.
Longitudinal dynamics of clonal haematopoiesis identifies gene-specific fitness effects
GEO Series GSE178936. Homo sapiens. 261 samples. Type: Other.
The impact of small molecule inhibition of METTL3 on normal haematopoiesis
GEO Series GSE228562. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis
GEO Series GSE259404. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Human yolk sac-like haematopoiesis generates RUNX1-, GFI1- and/or GFI1B-dependent blood and SOX17-positive endothelium
GEO Series GSE124085. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
GATA2 mitotic bookmarking is required for definitive haematopoiesis [ChIP-seq]
GEO Series GSE207551. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
EZH1 as a key epigenetic barrier to definitive haematopoiesis during embryonic development
GEO Series GSE89418. Mus musculus; Homo sapiens. 58 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Systematic screening of chromatin factors identifies divergent roles across haematopoiesis and leukaemia [scRNA-Seq]
GEO Series GSE213511. Mus musculus. 68 samples. Type: Expression profiling by high throughput sequencing.
Aberrant haematopoiesis in Dnmt2 mutant mice [HTS 2]
GEO Series GSE65757. Mus musculus. 8 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Atypical chemokine receptor 1 controls haematopoiesis
GEO Series GSE86349. Mus musculus. 8 samples. Type: Expression profiling by array.
Human yolk sac-like haematopoiesis generates RUNX1-, GFI1- and/or GFI1B-dependent blood and SOX17-positive endothelium
GEO Series GSE124084. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Decoding the regulatory circuit by epigenetic regulator MOF in haematopoiesis
GEO Series GSE107154. Mus musculus. 68 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Inferring rules of lineage commitment in haematopoiesis
GEO Series GSE34605. Mus musculus. 26 samples. Type: Expression profiling by array.
Microbial metabolite drives ageing-related clonal haematopoiesis via ALPK1 [RNA-seq]
GEO Series GSE232794. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Enhancers of Polycomb 1 & 2 in normal and leukaemic haematopoiesis
GEO Series GSE39172. Mus musculus. 18 samples. Type: Expression profiling by array.
Effect of Ythdf2 in haematopoiesis [RNA-seq]
GEO Series GSE142019. Mus musculus. 34 samples. Type: Expression profiling by high throughput sequencing.
Childhood brain tumors instruct cranial haematopoiesis and immunotolerance [endpoint Fus1 GEX]
GEO Series GSE300889. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.