Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
84
datasets available to search
ShareScore release 0.9.0
Dataset results
84 results for “Heart remodeling”
A cross-study transcriptional patient map of heart failure defines conserved multicellular coordination in cardiac remodeling
<p>Collection of auxiliary data to reproduce the results from "<strong>A cross-study transcriptional patient map of heart failure defines conserved multicellular coordination in cardiac remodeling</strong>". Source code is available at: https://github.com/saezlab/reheat2_pub<br><br>We provide processed data to facilitate access to the results, for the original count data, please see the associated manuscript for references to the original datasets. </p> <p> </p> <p> </p>
Data deposition for Complex electrophysiological remodeling in postinfarction ischemic heart failure
Open the record for dataset details and reuse information.
Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart
ClinicalTrials.gov study NCT01798992. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Data from: Functional remodelling of perinuclear mitochondria alters nucleoplasmic Ca2+ signalling in heart failure
Open the record for dataset details and reuse information.
Effects of Eplerenone on Left Ventricular Remodelling Following Heart Attack
ClinicalTrials.gov study NCT00132093. IPD Sharing: Not stated. Countries: 1. Publications: 11.
The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure
ClinicalTrials.gov study NCT00043836. IPD Sharing: Not stated. Countries: 1. Publications: 16.
IK-5001 for the Prevention of Remodeling of the Ventricle and Congestive Heart Failure After Acute Myocardial Infarction
ClinicalTrials.gov study NCT01226563. IPD Sharing: NO. Countries: 9. Publications: 3.
Determinants of Right Heart Remodeling in Patients With CTEPH or PAH
ClinicalTrials.gov study NCT03205085. IPD Sharing: NO. Countries: 1. Publications: 1.
Impact on Atrial Remodeling of Dapaglifozin in Patients With Heart Failure .
ClinicalTrials.gov study NCT04707352. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Impact of TORasemide oN hemodynAmic and Neurohormonal Stress, and carDiac remOdeling in Heart Failure
ClinicalTrials.gov study NCT01942109. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Raw data for the article: MicroRNA-30d and -483-3p for bi-ventricular remodelling and miR-126-3p for pulmonary hypertension in advanced heart failure
<p><strong>Aims: </strong>MicroRNAs play a role in pathogenic mechanisms leading to heart failure. We measured a panel of 754 miRNAs in the myocardial tissue and in the serum of patients with heart failure with reduced ejection fraction due to dilatative idiopathic cardiomyopathy (DCM, N = 10) or ischaemic cardiomyopathy (N = 3), referred to left ventricular assist device implant. We aim to identify circulating miRNAs with high tissue co-expression, significantly associated to echocardiographic and haemodynamic measures.</p> <p><strong>Methods and results: </strong>We have measured a panel of 754 miRNAs in the myocardial tissue [left ventricular (LV) apex] and in the serum obtained at the same time in a well selected study population of end-stage heart failure with reduced ejection fraction due to either DCM or ischaemic cardiomyopathy, referred to continuous flow left ventricular assist device implant. We observed moderate agreement for miR-30d, miR-126-3p, and miR-483-3p. MiR-30d was correlated to LV systolic as well as diastolic volumes (r = 0.78, P = 0.001 and r = 0.80, P = 0.005, respectively), while miR-126-3p was associated to mPAP and PCWP (r = -0.79, P = 0.007 and r = -0.80, P = 0.005, respectively). Finally, serum miR-483-3p had an association with right ventricular end diastolic diameter (r = -0.73, P = 0.02) and central venous pressure (CVP) (r - 0.68 p 0.03).</p> <p><strong>Conclusions: </strong>In patients with DCM, few miRNAs are co-expressed in serum and tissue: They are related to LV remodelling (miR-30d), post-capillary pulmonary artery pressure (miR-126-3p), and right ventricular remodelling/filling pressures (miR-483-3p). Further studies are needed to confirm their role in diagnosis, prognosis or as therapeutic targets in heart failure with reduced ejection fraction.</p>
Evaluation of the Effect of Injectable Neucardin on Cardiac Function and Reversal Ventricular Remodeling in Patients With Chronic Systolic Heart Failure
ClinicalTrials.gov study NCT05949801. IPD Sharing: NO. Countries: 1. Publications: 0.
MicroRNA-31 promotes adverse cardiac remodeling and dysfunction in ischemic heart disease.
GEO Series GSE81636. Rattus norvegicus. 4 samples. Type: Non-coding RNA profiling by array.
A Porcine Model of Heart Failure With Preserved Ejection Fraction Induced by Chronic Pressure Overload Characterized by Cardiac Fibrosis and Remodeling
GEO Series GSE167643. Sus scrofa. 6 samples. Type: Expression profiling by high throughput sequencing.
Ventricular T-box 5 in the adult heart ensures normal cardiac conduction and protects from pathologic cardiac remodeling [ChIP-seq]
GEO Series GSE101614. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Ventricular T-box 5 in the adult heart ensures normal cardiac conduction and protects from pathologic cardiac remodeling
GEO Series GSE101615. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice
GEO Series GSE138062. Mus musculus. 16 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing.
Shared gene expression profiles in developmental heart valve remodeling and osteoblast progenitor cells
GEO Series GSE11040. Mus musculus. 6 samples. Type: Expression profiling by array.
A context-specific cardiac Beta-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart [RNA-eq]
GEO Series GSE97762. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Proline metabolic reprogramming modulates cardiac remodeling induced by pressure overload in the heart
GEO Series GSE260464. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.