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20 results for “Homeostatic plasticity”
The Interplay between Hebbian and homeostatic plasticity in the Adult Visual cortex
<p>Data linked to the article "The interplay between Hebbian and homeostatic plasticity in the adult visual cortex", Journal of Physiology, DOI: <a href="https://doi.org/10.1113/JP287665">https://doi.org/10.1113/JP287665</a></p> <p>Data from binocular rivalry measurements and processed data from EEG Visual Evoked Potentials (VEP) are separated in different files.</p> <p>The ocular dominance index (ODI) files are split in two: the "ODI_values" file contains the raw measurements from participants, and the "change_from_baseline file" contains the same data normalized to baseline for each measurement.</p> <p>In both files, each column refers to a different measurement and condition:</p> <p>noHFS: data measured with the 17Hz HFS block before monocular deprivation<br>HFS: data measured with the 8.6Hz HFS block before monocular deprivation</p> <p>Baseline: Ocular dominance index measured at the start of the session, before any manipulation<br>Post_MD_1: first measurement after 60 minutes monocular deprivation (starting immediately after the end of deprivation)<br>Post_MD_2: second measurement after 60 minutes monocular deprivation (starting 11 minutes after the end of deprivation)<br>Post_MD_3: third measurement after 60 minutes monocular deprivation (starting 22 minutes after the end of deprivation)</p> <p>In VEP files, each column refers to a different condition:</p> <p>HFS: VEP recorded in the high-frequency stimulation condition, no monocular deprivation<br>HFS_MD: VEP recorded in the high-frequency stimulation condition with monocular deprivation<br>noHFS: VEP recorded in the condition where the HFS block was withheld, as a control for its role in our effect</p> <p>pre: first 500 measurements, before the High-Frequency Stimulation (HFS) block<br>post: last 500 measurements, after the HFS block (or after the break in the noHFS condition).</p>
Denervated mouse CA1 pyramidal neurons express homeostatic synaptic plasticity following entorhinal cortex lesion
<p><span>Structural, functional, and molecular reorganization of denervated neural networks is often observed in neurological conditions. The loss of input is accompanied by homeostatic synaptic adaptations, which can affect the reorganization process. A major challenge of denervation-induced homeostatic plasticity operating in complex neural networks is the specialization of neuronal inputs. It remains unclear whether neurons respond similarly to the loss of distinct inputs. Here, we used <em>in</em> <em>vitro</em> entorhinal cortex lesion (ECL) and Schaffer collateral lesion (SCL) in mouse organotypic entorhino-hippocampal tissue cultures to study denervation-induced plasticity of CA1 pyramidal neurons. We observed microglia accumulation, presynaptic bouton degeneration, and a reduction in dendritic spine numbers in the denervated layers three days after SCL and ECL. Transcriptome analysis of the CA1 region revealed complex changes in differential gene expression following SCL and ECL compared to non-lesioned controls with a specific enrichment of differentially expressed synapse-related genes observed after ECL. Consistent with this finding, denervation-induced homeostatic plasticity of excitatory synapses was observed three days after ECL but not after SCL. Chemogenetic silencing of the EC but not CA3 confirmed the pathway-specific induction of homeostatic synaptic plasticity in CA1. Additionally, increased RNA oxidation was observed after SCL and ECL. These results reveal important commonalities and differences between distinct pathway lesions and demonstrate a pathway-specific induction of denervation-induced homeostatic synaptic plasticity. </span></p>
Quantitative Multiplex Immunoprecipitation (QMI) analysis of protein interaction network rearrangements during homeostatic plasticity
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Denervated mouse CA1 pyramidal neurons express homeostatic synaptic plasticity following entorhinal cortex lesion
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Aftereffects and Reliability of Two Homeostatic Plasticity Induction Protocols
ClinicalTrials.gov study NCT04324801. IPD Sharing: NO. Countries: 1. Publications: 5.
The Effect of Capsaicin-induced Pain on Homeostatic Plasticity in Healthy Human Participants
ClinicalTrials.gov study NCT04485689. IPD Sharing: NO. Countries: 1. Publications: 5.
The Effects of Immobilisation and Exercise on Homeostatic Plasticity Mechanisms in Healthy Participants
ClinicalTrials.gov study NCT05252247. IPD Sharing: NO. Countries: 1. Publications: 4.
Regulating Homeostatic Plasticity and the Physiological Response to rTMS
ClinicalTrials.gov study NCT03309696. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Persistence of homeostatic sleep drive is encoded by plasticity of a thalamic reuniens circuit
GEO Series GSE245537. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Denervated mouse CA1 pyramidal neurons express homeostatic synaptic plasticity following entorhinal cortex lesion
GEO Series GSE223096. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
Probing Homeostatic Plasticity With Priming Theta-burst Stimulation of the Dorsolateral Prefrontal Cortex
ClinicalTrials.gov study NCT04031105. IPD Sharing: NO. Countries: 1. Publications: 0.
N-methyl-D-aspartate receptors mediate activity-dependent down-regulation of potassium channel genes during the expression of homeostatic intrinsic plasticity
GEO Series GSE104052. Rattus norvegicus. 12 samples. Type: Expression profiling by array.
A model for studying homeostatic plasticity in human stem cell derived neuronal networks
GEO Series GSE225761. Rattus norvegicus; Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus
GEO Series GSE161540. Rattus norvegicus. 10 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomics analysis of heterozygous mutant and wild-type flies for presynaptic homeostatic plasticity
GEO Series GSE153225. Drosophila melanogaster. 23 samples. Type: Expression profiling by high throughput sequencing.
microRNA-218-5p Coordinates Scaling of Excitatory and Inhibitory Synapses during Homeostatic Synaptic Plasticity
GEO Series GSE245158. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Division of labor among H3K4 Methyltransferases Define Distinct Facets of Homeostatic Plasticity
GEO Series GSE239471. Mus musculus. 21 samples. Type: Other.
HIV-1 perturbs homeostatic ILCs, unmasks ILC1 plasticity, and boosts TCF7+ memory NK cells
GEO Series GSE97727. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Antiepileptic medication induces homeostatic synaptic plasticity in pyramidal neurons of the adult human neocortex
GEO Series GSE244095. Homo sapiens; Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Intrinsic Homeostatic Plasticity in Mouse and Human Sensory Neurons
GEO Series GSE236109. Mus musculus; Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.