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Dataset results
253 results for “Hospital infections”
Epidemiology, risk factors and clinical course of SARS-CoV-2 infected patients in a Swiss university hospital: an observational retrospective study
<p>This is the dataset of the study called "Epidemiology, risk factors and clinical course of SARS-CoV-2 infected patients in a Swiss university hospital: an observational retrospective study". <br> <br> <strong>Abstract: </strong></p> <p>Background<br> Coronavirus disease 2019 (COVID-19) is now a global pandemic with Europe and the USA at its epicenter. Little is known about risk factors for progression to severe disease in Europe. This study aims to describe the epidemiology of COVID-19 patients in a Swiss university hospital.</p> <p>Methods<br> This retrospective observational study included all adult patients hospitalized with a laboratory confirmed SARS-CoV-2 infection from March 1 to March 25, 2020. We extracted data from electronic health records. The primary outcome was the need to mechanical ventilation at day 14. We used multivariate logistic regression to identify risk factors for mechanical ventilation. Follow-up was of at least 14 days. <br> <br> Results<br> 200 patients were included, of whom 37 (18·5%) needed mechanical ventilation at 14 days. The median time from symptoms onset to mechanical ventilation was 9·5 days (IQR 7.00, 12.75). Multivariable regression showed increased odds of mechanical ventilation in males (3.26, 1.21-9.8; p=0.025), in patients who presented with a qSOFA score ≥2 (6.02, 2.09-18.82; p=0.001), with bilateral infiltrate (5.75, 1.91-21.06; p=0.004) or with a CRP of 40 mg/l or greater (4.73, 1.51-18.58; p=0.013). <br> <br> Conclusions<br> This study gives some insight in the epidemiology and clinical course of patients admitted in a European tertiary hospital with SARS-CoV-2 infection. Male sex, high qSOFA score, CRP of 40 mg/l or greater and a bilateral radiological infiltrate could help clinicians identify patients at high risk for mechanical ventilation.</p>
Python codes for deconstructing the effects of stochasticity on transmission of hospital-acquired infections in ICUs
<p>The inherent stochasticity in transmission of hospital-acquired infections (HAIs) has complicated our understanding of transmission pathways. It is particularly difficult to detect the impact of changes in the environment on the acquisition rate due to stochasticity. In this study, we investigated the impact of uncertainty (epistemic and aleatory) on nosocomial transmission of HAIs by evaluating the effects of stochasticity on the detectability of seasonality on admission. For doing so, we developed an agent-based model of an ICU and simulated the acquisition of HAIs considering the uncertainties in the behavior of the healthcare workers (HCWs) and transmission of pathogens between patients, HCWs, and the environment. Our results show that stochasticity in HAI transmission weakens our ability to detect the effects of a change, such as seasonality, on the acquisition rate, particularly when transmission is a low-probability event. In addition, our findings demonstrate that data compilation can address this issue, while the amount of required data depends on the size of the said change and the amount of stochasticity. Our methodology can be used as a framework to assess the impact of interventions and provide decision-makers with insight about the minimum required size and target of interventions in a healthcare facility.</p>
Study of a Single Intramuscular Dose of Nirsevimab in the Prevention of Hospitalizations Due to Respiratory Syncytial Virus (RSV) Infection in Healthy Term and Preterm Infants During the First Year of
ClinicalTrials.gov study NCT05437510. IPD Sharing: YES. Countries: 3. Publications: 2.
Python codes for deconstructing the effects of stochasticity on transmission of hospital-acquired infections in ICUs
Open the record for dataset details and reuse information.
Geographic and specialty antibiotic prescribing in Medicare Part D, and its relationship with hospital acquired infections
<p>Datasets analyzed in the paper: Geographic and specialty antibiotic prescribing in Medicare Part D, and its relationship with hospital acquired infections.</p>
Rotavirus infection and health related quality of life of hospitalized children in Latvia
<p>Data on Rotavirus infection and health related quality of life of hospitalized children in Latvia, 527 respondents, anonymous data, data collected: April 2013 to December 2015.</p>
Undiagnosed Hepatitis C Infection in an Urban Hospital
ClinicalTrials.gov study NCT01957085. IPD Sharing: NO. Countries: 1. Publications: 3.
Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization
ClinicalTrials.gov study NCT03118232. IPD Sharing: NO. Countries: 1. Publications: 1.
Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)
ClinicalTrials.gov study NCT01595438. IPD Sharing: Not stated. Countries: 22. Publications: 5.
Safety Study to Assess IV Zanamivir for Treatment of Influenza Infection in Patients Who Are in Hospital
ClinicalTrials.gov study NCT01014988. IPD Sharing: YES. Countries: 13. Publications: 1.
Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections
ClinicalTrials.gov study NCT03445195. IPD Sharing: NO. Countries: 1. Publications: 1.
Reducing Post-Hospital Mortality in HIV-infected Adults in Tanzania
ClinicalTrials.gov study NCT03858998. IPD Sharing: YES. Countries: 1. Publications: 4.
Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)
ClinicalTrials.gov study NCT01599806. IPD Sharing: Not stated. Countries: 17. Publications: 6.
Covid-19 Infection and Pulmonary Distress Treatment With Zanubrutinib in Hospitalized Participants
ClinicalTrials.gov study NCT04382586. IPD Sharing: YES. Countries: 1. Publications: 1.
Hand Hygiene and Hospital Acquired Infections
ClinicalTrials.gov study NCT02252562. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Convalescent Plasma as Treatment for Hospitalized Subjects With COVID-19 Infection
ClinicalTrials.gov study NCT04343755. IPD Sharing: NO. Countries: 1. Publications: 19.
A Study of Intravenous Zanamivir in the Treatment of Hospitalized Patients With Influenza Infection
ClinicalTrials.gov study NCT01527110. IPD Sharing: YES. Countries: 1. Publications: 1.
AssessmeNT of the Incidence of Clostridium Difficile Infections in Hospitalized Patients on Antibiotic TrEatment
ClinicalTrials.gov study NCT02896244. IPD Sharing: NO. Countries: 6. Publications: 2.
A Study to Evaluate the Efficacy and Safety of Pimodivir in Combination With the Standard-of-Care Treatment in Adolescent, Adult, and Elderly Hospitalized Participants With Influenza A Infection
ClinicalTrials.gov study NCT03376321. IPD Sharing: Not stated. Countries: 38. Publications: 2.
Compare Ceftazidime-Avibactam + Metronidazole vs Meropenem for Hospitalized Adults With Complicated Intra-Abd Infections
ClinicalTrials.gov study NCT01726023. IPD Sharing: Not stated. Countries: 3. Publications: 6.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.