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9 results for “Hydractinia”
Hydractinia strain 236-21 genome assembly and Alr domain predictions
<p>This dataset is related to the preprint "A family of unusual A family of unusual immunoglobulin superfamily genes in an invertebrate histocompatibility complex" (<a href="https://www.biorxiv.org/content/10.1101/2022.03.04.482883v2">https://www.biorxiv.org/content/10.1101/2022.03.04.482883v2</a>).</p> <p><strong>Preprint Abstract:</strong></p> <p>Most colonial marine invertebrates are capable of allorecognition, the ability to distinguish between themselves and conspecifics. One long-standing question is whether invertebrate allorecognition genes are homologous to vertebrate histocompatibility genes. In the cnidarian <em>Hydractinia symbiolongicarpus, </em>allorecognition is controlled by at least two genes, <em>Allorecognition 1</em> (<em>Alr1</em>) and <em>Allorecognition 2 </em>(<em>Alr2</em>), which encode highly polymorphic cell surface proteins that serve as markers of self. Here, we show that <em>Alr1</em> and <em>Alr2</em> are part of a family of 41 <em>Alr </em>genes, all of which reside a single genomic interval called the Allorecognition Complex (ARC). Using sensitive homology searches and highly accurate structural predictions, we demonstrate that the Alr proteins are members of the immunoglobulin superfamily (IgSF) with V-set and I-set Ig domains unlike any previously identified in animals. Specifically, their primary amino acid sequences lack many of the motifs considered diagnostic for V-set and I-set domains, yet they adopt secondary and tertiary structures nearly identical to canonical Ig domains. Thus, the V-set domain, which played a central role in the evolution of vertebrate adaptive immunity, was present in the last common ancestor of cnidarians and bilaterians. Unexpectedly, several Alr proteins also have immunoreceptor tyrosine-based activation motifs (ITAMs) and immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic tails, suggesting they could participate in pathways homologous to those that regulate immunity in humans and flies. This work expands our definition of the IgSF with the addition of a family of unusual members, several of which play a role in invertebrate histocompatibility.</p> <p><strong>This dataset contains:</strong></p> <ol> <li><strong>Hsym-236-21-genome-assembly.fa.gz</strong>: A gzip-compressed FASTA-formatted file of the genome assembly generated in the paper. </li> <li><strong>Alr-domain-structure-predictions.zip:</strong> a zip-compressed file with structural predictions produced with Colabfold for all domains of the Alr proteins described in that manuscript.</li> </ol>
Hydractinia symbiolongicarpus genome and transcriptome assemblies
<p>Scaffold-level genome assemblies for Hydractinia symbiolongicarpus histoincompatible siblings BC-3 and BC-15 from a back-cross population derived from wildtype individuals . Assemblies generated with ABySS short read assembler using Illumina 200-bp insert paired-end libaries and 3-Kbp insert mate pair 'long jumping distance' libraries. The trimmed read depths were ~36X and ~49X for BC-3 and BC-15, respectively.</p> <p>Transcriptome assemblies for Hydractinia symbiolongicarpus wildtype individuals HWB-103 and HWB-29. Assemblies generated with Trinity using Illumina mRNA libraries.</p>
FIGURE 7. Hydractinia angusta Hartlaub, 1904 in Review of some little-known benthic hydroids (Cnidaria, Hydrozoa) from the Southern Ocean
FIGURE 7. Hydractinia angusta Hartlaub, 1904: A–C, gastrozooids; D–G, gonozooids with gonophores; H, spine. Hydractinia dendritica Hickson & Gravely, 1907: I, J, gastrozooids; K–M, gonozooids (L, M with gonophores); N, dactylozooid (J, M from paratype). Scale bar: 250 µm.
FIGURE 11 in Description and life cycle of the hydrozoan Hydractinia uniformis, sp. nov. (Cnidaria: Hydrozoa: Hydractiniidae), from the coast of southeastern Brazil
FIGURE 11. Schematic side view of a colony of Hydractinia uniformis, sp. nov. Note: the polyp tentacles are slightly retracted; the polyp on the right side is contracted and has frustules and medusa buds; the polyp on the left side has an older medusa bud. Scale = 500 µm.
FIGURE 5–10 in Description and life cycle of the hydrozoan Hydractinia uniformis, sp. nov. (Cnidaria: Hydrozoa: Hydractiniidae), from the coast of southeastern Brazil
FIGURE 5–10. Hydractinia uniformis, sp. nov. 5, side view of a newly released medusa; note the presence of only four tentacles. Scale = 350 µm. 6, side view of a 15dayold medusa; note the eigh tentacles. Scale = 550 µm. 7, side view of a 40dayold medusa; note the 16 tentacles. Scale = 950 µm. 8, side view of a mature medusa (~ 65 days old); note the 24 tentacles. Scale = 1.5 mm. 9, oral view of a mature medusa (~ 65 days old); note the 24 tentacles. Scale = 2 mm. 10, side view of the oral lips of a young medusa; note the branches with nematocysts knobs. Scale = 100 µm.
FIGURE 1–4 in Description and life cycle of the hydrozoan Hydractinia uniformis, sp. nov. (Cnidaria: Hydrozoa: Hydractiniidae), from the coast of southeastern Brazil
FIGURE 1–4. Overview of a polyp of Hydractinia uniformis, sp. nov. 1, showing the hydrorhiza and a medusa bud shortly before release. Scale = 1 mm. 2, showing a medusa bud and the nippleshaped hypostome. Scale = 0.5 mm. 3, side view (confocal microscopy) of a newly released medusa of Hydractinia uniformis, sp. nov. Scale = 200 µm. 4, oral view using confocal microscopy of a newly released medusa of Hydractinia uniformis, sp. nov. Scale = 200 µm.
Data from: Gene co-expression modules underlying polymorphic and monomorphic zooids in the colonial hydrozoan, Hydractinia symbiolongicarpus
Open the record for dataset details and reuse information.
The Hydractinia cell atlas reveals cellular and molecular principles of cnidarian coloniality
GEO Series GSE269914. Hydractinia symbiolongicarpus. 4 samples. Type: Expression profiling by high throughput sequencing.
Parallels and contrasts between the cnidarian and bilaterian maternal-to-zygotic transition are revealed in Hydractinia embryos
GEO Series GSE232065. Hydractinia symbiolongicarpus. 45 samples. Type: Expression profiling by high throughput sequencing.
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