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39 results for “Hypoxic response”
Anna's hummingbird (Calypte anna) physiological response to novel thermal and hypoxic conditions at high elevations
<p>Many species have not tracked their thermal niches upslope as predicted by climate change, potentially because higher elevations are associated with abiotic challenges beyond temperature. To better predict if organisms can continue to move upslope with rising temperatures, we need to understand their physiological performance when subjected to novel high elevation conditions. Here, we captured Anna's hummingbirds – a species expanding their elevational distribution in concordance with rising temperatures – from across their current elevational distribution and tested their physiological response to novel abiotic conditions. First, at a central aviary within their current elevational range, we measured hovering metabolic rate to assess their response to oxygen conditions and torpor use to assess their response to thermal conditions. Second, we transported the hummingbirds to a location 1200 meters above their current elevational range limit to test an acute response to novel oxygen and thermal conditions. Hummingbirds exhibited lower hovering metabolic rates above their current elevational range limit, suggesting lower oxygen availability may reduce performance after an acute exposure. Alternatively, hummingbirds showed a facultative response to thermal conditions by using torpor more frequently and longer. Finally, post-experimental dissection found that hummingbirds originating from higher elevations within their range had larger hearts, a potential plastic response to hypoxic environments. Overall, our results suggest lower oxygen availability and low air pressure may be difficult challenges to overcome for hummingbirds shifting upslope due to rising temperatures, especially if there is little to no long-term acclimatization. Future studies should investigate how chronic exposure and acclimatization to novel conditions, as opposed to acute experiments, may result in alternative outcomes that help organisms better respond to abiotic challenges associated climate-induced range shifts.</p>
Anna's hummingbird (Calypte anna) physiological response to novel thermal and hypoxic conditions at high elevations
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Iron Status and Hypoxic Pulmonary Vascular Responses
ClinicalTrials.gov study NCT01847352. IPD Sharing: NO. Countries: 1. Publications: 5.
Cardio-respiratory Responses During Hypoxic Exercise in Individuals Born Prematurely
ClinicalTrials.gov study NCT02780908. IPD Sharing: NO. Countries: 1. Publications: 9.
Data from: Adenosine receptors mediate the hypoxic ventilatory response but not the hypoxic metabolic response in the naked mole rat during acute hypoxia
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CX3CR1-Fractalkine Dysregulation Affects Retinal GFAP Expression, Inflammatory Gene Induction, and LPS Response in a Mouse Model of Hypoxic Retinopathy
GEO Series GSE276207. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomics and metabolomics study in mouse kidney of the molecular mechanism underlying energy metabolism response to hypoxic stress in highland areas
GEO Series GSE240049. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Loss of CSL unlocks a hypoxic response and enhanced tumor growth potential in breast cancer cells
GEO Series GSE77308. Homo sapiens. 404 samples. Type: Expression profiling by high throughput sequencing.
Gene expression analysis in response to hypoxic pathway inhibition
GEO Series GSE120675. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
KSHV Infection Mimics the Hypoxic Response Based on Next-Generation Sequencing [miRNA-Seq]
GEO Series GSE79030. Human gammaherpesvirus 8; Homo sapiens. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Histone methylation landscape in response to short hypoxic exposure
GEO Series GSE120339. Homo sapiens. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
small RNA sequencing for identifying hypoxic responsive miRNAs
GEO Series GSE79787. Homo sapiens. 4 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Hypoxic response for human bronchial epithelial culture [bulkRNA-Seq batch1]
GEO Series GSE227502. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Chronic hypoxic response for human bronchial epithelial culture [bulkRNA-Seq batch2]
GEO Series GSE227501. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Effect of Rocuronium on the Acute Hypoxic Ventilatory Response in Patients With Obstructive Sleep Apnea
ClinicalTrials.gov study NCT01672606. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Ventilatory Responses to Hypercapnic and Hypoxic Conditions in Hyperventilants
ClinicalTrials.gov study NCT05189158. IPD Sharing: NO. Countries: 1. Publications: 0.
Discrete and cell-specific hypoxic responses in Arabidopsis roots resolved by single-nuclei transcriptomics
GEO Series GSE308672. Arabidopsis thaliana. 4 samples. Type: Expression profiling by high throughput sequencing.
Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis
GEO Series GSE8829. Mycobacterium tuberculosis. 12 samples. Type: Expression profiling by array.
Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization
GEO Series GSE90599. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Ixr1 and the Saccharomyces cerevisiae hypoxic response
GEO Series GSE30046. Saccharomyces cerevisiae. 12 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.