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ShareScore release 0.9.0
Dataset results
9 results for “IFI16;”
IFI16 is a Periodontitis Modulating Protein
ClinicalTrials.gov study NCT03513497. IPD Sharing: YES. Countries: 1. Publications: 0.
Transcriptional response to drug-induced oligomerization of the AIM2-like receptors IFI16, PYHIN1, and MNDA.
GEO Series GSE80598. Homo sapiens. 12 samples. Type: Expression profiling by array.
Innate immune sensing of influenza virus through IFI16 promote pyroptosis.
GEO Series GSE163705. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Replication Stress in Hair-Follicle-Stem-Cell Leads to IFI16-STING dependent inflammation in Hidradenitis Suppurativa
GEO Series GSE147586. Homo sapiens. 11 samples. Type: Expression profiling by array.
IFI16 functions as an antiviral factor during influenza virus infection by binding viral RNA and enhancing the RIG-I signaling (RNA-seq)
GEO Series GSE157609. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Serum IFI16 and anti-IFI16 antibodies in psoriatic arthritis."
<p>Nuclear interferon-inducible protein 16 (IFI16) and anti-IFI16 antibodies have been detected in subjects with several rheumatic diseases, often correlating with disease severity, and in this study we investigated their prevalence and clinical associations in psoriatic arthritis (PsA) compared to psoriasis (Pso). We tested sera and synovial fluids of patients with PsA for IFI16 protein levels by capture enzyme-linked immunosorbent assay (ELISA) and for anti-IFI16 immunoglobulin (Ig)G and IgA by ELISA, protein radio-immunoprecipitation and immunoprecipitation-Western blot of IgG. Sera from patients with Pso and healthy subjects were used as controls, and in a subgroup of patients with PsA we also studied sera after treatment with etanercept. IFI16 was detectable in the sera of 66% of patients with Pso, 46% with PsA and 19% of controls. Among PsA cases, 51% of IFI16-positive cases had elevated levels of C-reactive protein (CRP) compared to 31% of patients with undetectable IFI16. Anti-IFI16 of both IgG and IgA isoforms were detected with significantly higher frequency in PsA and Pso compared to healthy controls, with higher IgG titres in patients with elevated C-reactive protein (CRP) (P = 0·015). Immunoprecipitation confirmed the presence of anti-IFI16 IgG antibodies and these preferentially recognized epitopes outside the N-terminus of the protein. Lastly, IFI16 was detected in one of seven and anti-IFI16 in three of seven synovial fluids from patients with PsA. Therefore, IFI16 and anti-IFI16 are detectable in serum and synovial fluid of PsA patients, especially in cases of elevated CRP.</p>
IFI16-mediated cellular senescence drives HMOX1-dependent evasion of ferroptosis and radioresistance in glioblastoma
GEO Series GSE274090. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
IFI16 functions as an antiviral factor during influenza virus infection by binding viral RNA and enhancing the RIG-I signaling
GEO Series GSE158123. Influenza A virus; Homo sapiens. 11 samples. Type: Other; Expression profiling by high throughput sequencing.
IFI16 functions as an antiviral factor during influenza virus infection by binding viral RNA and enhancing the RIG-I signaling (RIP-seq)
GEO Series GSE158122. Influenza A virus; Homo sapiens. 3 samples. Type: Other.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.