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88 results for “IGF-1”
Ensemble and single cell data for primary Ovis Aries pulmonary artery endothelial cells response to IGF-1 administration
<p>Data for IGF-1 administration of healthy and persistent pulmonary hypertension of the newborn primary Ovis Aries pulmonary artery endothelial cells.</p> <p>Ensemble.zip:<br> Dose-response to IGF-1<br> Proliferation<br> Western blots for VEGF and eNOS<br> IGF-1R and mTOR inhibition<br> Branch points in tube formation assay<br> <br> IF.zip:<br> Cellprofiler 3.1 analysis of snapshot data for the time course of IGF-1 administration with nuclei, actin, VEGF, and eNOS</p> <p>Translation.zip:<br> CellProfiler 3.1 analysis of snapshot data for the time course of IGF-1 administration with nuclei and total protein production</p>
Data from: Juvenile concentrations of IGF-1 predict life-history trade-offs in a wild mammal
Early postnatal development can have profound effects on life-history traits later in life. One mechanism hypothesized to mediate this relationship is the anabolic hormone, insulin-like growth factor-1 (IGF-1). IGF-1 contributes importantly to postnatal growth, and thus offers a means by which environmental and genetic variation might direct organismal development, reproduction and survival. We tested whether juvenile concentrations of IGF-1 can predict intraspecific variation in life-history traits later in life using longitudinal data from free-living female spotted hyenas (Crocuta crocuta). We found that juvenile concentrations of IGF-1 predicted heavier juvenile mass, which in turn predicted greater survival to reproductive maturity. However, independent of mass, higher juvenile concentrations of IGF-1 predicted earlier age at first parturition and reduced longevity in adulthood. Our results highlight the importance of early postnatal development as a determination period in mammals and suggest that concentrations of IGF-1 during this sensitive period can be used to predict important later-life trade-offs between growth, reproductive fitness and life span in wild, long-lived animals.
Survivorship Promotion In Reducing IGF-1 Trial
ClinicalTrials.gov study NCT02431676. IPD Sharing: NO. Countries: 1. Publications: 5.
Safety Profile of Insulin Like Growth Factor-1 (IGF-I) Administration in Adolescents
ClinicalTrials.gov study NCT00516386. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect Of Ophiochepalus Striatus Extract On Serum IGF-1 And IL-6 Levels In Elderly Patients With Sarcopenia
ClinicalTrials.gov study NCT05869383. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in Blood
ClinicalTrials.gov study NCT00212758. IPD Sharing: Not stated. Countries: 1. Publications: 2.
IGF-1/IGFBP3 Prevention of Retinopathy of Prematurity
ClinicalTrials.gov study NCT01096784. IPD Sharing: Not stated. Countries: 6. Publications: 7.
A Pilot Treatment Study of Insulin-Like Growth Factor-1 (IGF-1) in Autism Spectrum Disorder
ClinicalTrials.gov study NCT01970345. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effects of Growth Hormone and IGF-1 on Anabolic Signals and Stem Cell Recruitment in Human Skeletal Muscle
ClinicalTrials.gov study NCT03878992. IPD Sharing: NO. Countries: 1. Publications: 12.
Treatment of Rett Syndrome With Recombinant Human IGF-1
ClinicalTrials.gov study NCT01777542. IPD Sharing: Not stated. Countries: 1. Publications: 57.
Impact of an integrated intervention package during preconception, pregnancy, and early childhood on inflammation, IGF-1, IGFBP3 during the first 6 months of life: Findings from the WINGS randomized controlled trial
Open the record for dataset details and reuse information.
Data from: Juvenile concentrations of IGF-1 predict life-history trade-offs in a wild mammal
Open the record for dataset details and reuse information.
Growth Hormone as Add-on Treatment in Severe Fibromyalgia With Low IGF-1 Serum Levels (56 Characters)
ClinicalTrials.gov study NCT00497562. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Effect of a High Protein Diet on the 24-hour Profile of Ghrelin, GH (Growth Hormone) and IGF-1 (Insulin-like Growth Factor-1)
ClinicalTrials.gov study NCT00108225. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Growth Hormone, IGF-1 and Medical Treatment in Acromegaly: Are There Effects on Gut Hormone Physiology and Postprandial Substrate Metabolism?
ClinicalTrials.gov study NCT02152124. IPD Sharing: Not stated. Countries: 1. Publications: 16.
Effect of a HIIT Program on Quality of Life, Executive Functions, and IGF-1 Response in Sedentary Young University Women
ClinicalTrials.gov study NCT05642169. IPD Sharing: NO. Countries: 1. Publications: 1.
A New Marker for Early Diagnosis of Pneumoperitoneum-Related Acute Kidney Injury: Insulin-Like Growth Factor-1 (IGF-1)
ClinicalTrials.gov study NCT05612802. IPD Sharing: NO. Countries: 1. Publications: 4.
IGF-1 Treatment for Individuals With Short Stature Due to PAPP-A2 Deficiency
ClinicalTrials.gov study NCT02636270. IPD Sharing: YES. Countries: 0. Publications: 2.
A Dose Escalating Clinical Trial of the IGF-1 Receptor Inhibitor AXL1717 in Patients With Advanced Cancer
ClinicalTrials.gov study NCT01062620. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Growth Hormone Secretagogue MK-0677 Effect on IGF-1 Levels in ESRD Patients
ClinicalTrials.gov study NCT00395291. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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