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opencc-by-4.0Oct 2020View details →

ROB 2 assessments_Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19_a living systematic review

Risk of bias assessments and support for judgement with ROB 2 tool for the Cochrane Review: Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19:a living systematic review (Version 3).

opencc-by-sa-4.0Jul 2014View details →

High-Throughput Sequencing of Human Immunoglobulin Variable Regions with Subtype Identification

Raw Illumina MiSeq data in zipped FASTQ format. The data set includes demultiplexed samples from three different time points (_wk*_) of patient ZA159 (159_*), samples from four different preps of a healthy donor (HD1_*), and samples from IgG subtype sorted cells of a healthy donor (HD3_*). Every sample consists of forward (_R1_), reverse (_R2_) and index read 1 (_I1_).

opencc-by-4.0Sep 2022View details →

Expression of immunoglobulin constant domain genes in neurons of the mouse central nervous system

Data related to the publication "Expression of immunoglobulin constant domain genes in neurons of the mouse central nervous system".  The fasta file (.fa) contains the sequence of neuronal FC-Ighm The .pdb files contain the model of the two different protein versions of Ighm The excel file contains the data of the quantification of co-expression and the ATG prediction results.

Figure 3 in Seasonal variations in immunoreactive cortisol and fecal immunoglobulin levels in Sichuan golden monkey (Rhinopithecus roxellana)

Figure 3. The immunoreactive cortisol concentrations of Sichuan golden monkeys within seasons (ng/g). Sp: Spring; Su: summer; Au: autumn; Wi: winter. FM refers to the mean of nonpregnant females (F1 and F2); MM refers to the mean of males (M1, M2, and M3). *,#, §,﹠: P <0.05, bar with * was significantly higher than bar with #, and bar with § was significantly higher than bar with ﹠.

Figure 5 in Seasonal variations in immunoreactive cortisol and fecal immunoglobulin levels in Sichuan golden monkey (Rhinopithecus roxellana)

Figure 5. The fecal immunoglobulin levels of Sichuan golden monkeys over the year (ng/g). FM refers to mean of nonpregnant females (F1 and F2); MM refers to mean of males (M1, M2, and M3).

Figure 2 in Seasonal variations in immunoreactive cortisol and fecal immunoglobulin levels in Sichuan golden monkey (Rhinopithecus roxellana)

Figure 2. Immunoreactive cortisol concentrations in males (M1 was the dominant male; M2 and M3 were all-male units) within seasons (ng/g). Sp: Spring; Su: summer; Au: autumn; Wi: winter. a,b,c,d: Histograms that share the same letters do not differ from each other, whereas histograms with different letters are different at P <0.05. *,#: P <0.05, bar with # was significantly higher than bar with *.

Figure 1 in Seasonal variations in immunoreactive cortisol and fecal immunoglobulin levels in Sichuan golden monkey (Rhinopithecus roxellana)

Figure 1. Immunoreactive cortisol concentrations in nonpregnant (F1 and F2) and pregnant (F3) females within seasons (ng/g). Sp: spring; Su: summer; Au: autumn; Wi: winter. a,b,c,d: Histograms that share the same letters do not differ from each other, whereas histograms with different letters are different at P <0.05. *,#: P <0.05, bar with * was significantly higher than bar with #.

Figure 4 in Seasonal variations in immunoreactive cortisol and fecal immunoglobulin levels in Sichuan golden monkey (Rhinopithecus roxellana)

Figure 4. The immunoreactive cortisol concentrations of Sichuan golden monkeys over the year (ng/g). FM refers to mean of nonpregnant females (F1 and F2); MM refers to mean of males (M1, M2, and M3).

opencc-by-4.0Aug 2020View details →

Fig. 2 in The non-invasive measurement of faecal immunoglobulin in African equids

Fig. 2. IgA was higher in Grevy's zebras than donkeys and, when other factors were taken into account in the zebra model, Grevy's zebra IgA was higher than plains zebra IgA. Conversely, FEC was higher in donkeys than the other two species (and at the population level plains zebras have higher FEC than Grevy's zebras; DIR and KJT unpublished data, Rubenstein et al., 2010). Horizontal bars indicate means, horizontal box edges standard errors, and asterisks and symbols above the brackets denote level of significance for differences that emerged in simple tests (ANOVA with Tukey post hoc for sqrtIgA, Kruskal-Wallis with Dunn's post hoc for FEC; p <0.05*, p <0.01**, p <0.001***).

opencc-by-4.0Aug 2020View details →

Fig. 3 in The non-invasive measurement of faecal immunoglobulin in African equids

Fig. 3. In donkeys, FEC and IgA are correlated among individuals in high body condition (with a body condition score> 2.5), in data pooled across years. Shading represents standard error, significant correlations are shown in solid lines, and non-significant trends in dotted lines.

opencc-by-4.0Aug 2020View details →

Fig. 1 in The non-invasive measurement of faecal immunoglobulin in African equids

Fig. 1. In donkeys, IgA increased with logFEC but only in 2018, when rainfall was higher. Shading represents standard error, significant correlations are shown in solid lines, and non-significant trends in dotted lines.

opencc-by-4.0Feb 2022View details →

Seroprevalence of immunoglobulin G antibodies against SARS-CoV-2 in Cyprus

Four vaccines that have been authorized in the European Union offer different levels of protection against SARS-CoV-2 by generating immune responses against the spike receptor-binding domain (RBD) of the virus. Monitoring the levels of IgG antibodies against the SARS-CoV-2 is important during the coronavirus disease 2019 (COVID-19) pandemic to plan an adequate and evidence-based public health response. We compared the levels of serum IgG antibodies against SARS-CoV-2 spike protein in three groups: i) individuals without evidence of prior infection with SARS-CoV-2 who received one or two doses of either an mRNA-based (Comirnaty BNT162b2/Pfizer-BioNTech or Spikevax mRNA-1273/Moderna) or an adenoviral-based vaccine (Vaxzervia ChAdOx1 nCoV-19 /Oxford-Astra Zeneca) (n=227), ii) unvaccinated individuals with evidence of prior infection with SARS-CoV-2 (n=109), and iii) individuals with evidence of prior infection with SARS-CoV-2 who received at least one dose of a vaccine (n=30). Unvaccinated individuals without evidence of prior infection with SARS-CoV-2 were used as a control group (n=211). Our results indicate that vaccine-induced responses lead to higher levels of IgG antibodies compared to those produced following infection with the virus. In agreement with previous studies, our results suggest that among individuals previously infected with SARS-CoV-2, even a single dose of a vaccine is adequate to elicit high levels of humoral immunity.

opencc-by-4.0Nov 2023View details →

Data supporting publication "Metagenomic Immunoglobulin Sequencing (MIG-Seq) Exposes Patterns of IgA Antibody Binding in the Healthy Human Gut Microbiome"

Data supporting publication "Metagenomic Immunoglobulin Sequencing (MIG-Seq) Exposes Patterns of IgA Antibody Binding in the Healthy Human Gut Microbiome"

opencc-by-4.0Jun 2019View details →

Interaction of hypertensive rat serum immunoglobulin with recombinant human proteins

Microsoft Excel file: “HuProt supplemental data.xlsx” Description of supplementary material : HuProt array v3.1 IgM and IgG signals from rat serum pools. Sheet 1: “Array Z scores” Z scores for all array features for all sample pools used in the study detected with anti-IgM and anti-IgG reporter antibodies Sheet 2: “IgM Z scores top 35” Z scores for the 35 array features that had highest scores detected with anti-IgM reporter in 28 week old salt loaded SHR-A3 and the corresponding scores for 16 week old SHR-A3 and 28 week old SHR-A3(IgH-B2) congenics. Sheet 3: “IgM Z scores higher at 28 wks” Refinement of Sheet 2 to eliminate array features in which IgM Z scores were greater in 16 week old SHR-A3 prior to salt loading compared with 28 week old salt-loaded SHR-A3. Sheet 4: “IgM Z scores congenics down” Refinement of Sheet 3 to include only array features in which IgM Z scores were reduced in 28 week old salt-loaded SHR-A3(IgH-B2) compared with 28 week old salt-loaded SHR-A3. Sheet 5: “IgG Z scores top 35” Z scores for the 35 array features that had highest scores detected with anti-IgG reporter in 28 week old salt loaded SHR-A3 and the corresponding scores for 16 week old SHR-A3 and 28 week old SHR-A3(IgH-B2) congenics. Sheet 6: “IgG Z scores higher at 28 wks” Refinement of Sheet 2 to eliminate array features in which IgG Z scores were greater in 16 week old SHR-A3 prior to salt loading compared with 28 week old salt-loaded SHR-A3. Sheet 7: “IgG Z scores congenics down” Refinement of Sheet 3 to include only array features in which IgG Z scores were reduced in 28 week old salt-loaded SHR-A3(IgH-B2) compared with 28 week old salt-loaded SHR-A3. Sheet 8: “Table 1 IgM IgG concordance” This data is presented as Table 1 in the manuscript and identifies those array features that are common to both Sheet 4 and Sheet 7, representing array features for which both IgM and IgG reactivity were reduced in 28 week old salt-loaded SHR-A3(IgH-B2) compared with 28 week old salt-loaded SHR-A3.